Baker Bros. Advisors

Latest statistics and disclosures from Baker Bros. Advisors's latest quarterly 13F-HR filing:

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Positions held by Baker Bros. Advisors consolidated in one spreadsheet with up to 7 years of data

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Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 84 positions in its portfolio as reported in the December 2023 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 25.8 $2.3B 36M 62.79
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BeiGene Sponsored Adr (BGNE) 21.7 $1.9B -9% 11M 180.36
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ACADIA Pharmaceuticals (ACAD) 15.3 $1.3B 43M 31.31
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Madrigal Pharmaceuticals (MDGL) 5.2 $456M +27% 2.0M 231.38
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Rhythm Pharmaceuticals (RYTM) 3.3 $294M -4% 6.4M 45.97
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Mirati Therapeutics (MRTX) 2.8 $242M +192% 4.1M 58.75
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Immunocore Holdings Ads (IMCR) 2.0 $172M 2.5M 68.32
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Kymera Therapeutics (KYMR) 1.7 $153M +26% 6.0M 25.46
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Revolution Medicines (RVMD) 1.7 $148M +91% 5.1M 28.68
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Invitae Corporation Notes 1.5% 4/1/2028 (Principal) 1.5 $131M 300M 0.44
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Abcellera Biologics (ABCL) 1.5 $131M +10% 23M 5.71
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Roivant Sciences SHS (ROIV) 1.0 $85M -36% 7.6M 11.23
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Replimune Group (REPL) 0.9 $81M +108% 9.5M 8.43
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Entrada Therapeutics (TRDA) 0.8 $73M 4.9M 15.09
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Ultragenyx Pharmaceutical (RARE) 0.8 $70M +7% 1.5M 47.82
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Cerevel Therapeutics Hldng I (CERE) 0.8 $68M NEW 1.6M 42.40
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Immatics SHS (IMTX) 0.7 $62M +3% 5.8M 10.53
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BioCryst Pharmaceuticals (BCRX) 0.7 $61M -20% 10M 5.99
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argenx SE Sponsored Adr (ARGX) 0.7 $58M 151k 380.43
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Denali Therapeutics (DNLI) 0.6 $56M +13% 2.6M 21.46
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Akero Therapeutics (AKRO) 0.6 $55M 2.4M 23.35
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Kodiak Sciences (KOD) 0.6 $53M 17M 3.04
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Kiniksa Pharmaceuticals Com Cl A (KNSA) 0.6 $49M 2.8M 17.54
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Xenon Pharmaceuticals (XENE) 0.5 $46M +32% 994k 46.06
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Prelude Therapeutics (PRLD) 0.5 $43M 10M 4.27
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Cerus Corporation (CERS) 0.5 $42M +12% 20M 2.16
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Nurix Therapeutics (NRIX) 0.5 $40M 3.9M 10.32
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Aerovate Therapeutics (AVTE) 0.4 $38M -14% 1.7M 22.63
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Ideaya Biosciences (IDYA) 0.4 $38M 1.1M 35.58
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Edgewise Therapeutics (EWTX) 0.4 $34M +196% 3.1M 10.94
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Sera Prognostics Class A Com (SERA) 0.4 $33M +258% 5.4M 5.98
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Bicycle Therapeutics Sponsored Ads (BCYC) 0.4 $32M +112% 1.8M 18.08
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Igm Biosciences (IGMS) 0.3 $31M +16% 3.7M 8.31
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Biomea Fusion (BMEA) 0.3 $31M 2.1M 14.52
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Monte Rosa Therapeutics (GLUE) 0.3 $28M 4.9M 5.65
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Verve Therapeutics (VERV) 0.3 $24M +19% 1.7M 13.94
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Krystal Biotech (KRYS) 0.2 $21M 170k 124.06
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Gracell Biotechnologies Sponsored Ads (GRCL) 0.2 $21M +108% 2.1M 10.04
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Immunovant (IMVT) 0.2 $18M 425k 42.13
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Tscan Therapeutics (TCRX) 0.2 $16M 2.8M 5.83
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Day One Biopharmaceuticals I (DAWN) 0.2 $15M 1.0M 14.60
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DBV Technologies Sponsored Adr (DBVT) 0.2 $14M 15M 0.95
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Relay Therapeutics (RLAY) 0.1 $13M 1.2M 11.01
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Silverback Therapeutics (SPRY) 0.1 $11M 2.0M 5.48
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Stoke Therapeutics (STOK) 0.1 $11M +36% 2.0M 5.26
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2seventy Bio (TSVT) 0.1 $11M 2.5M 4.27
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Insmed Incorporated Com Par $.01 (INSM) 0.1 $11M 343k 30.99
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Celldex Therapeutics (CLDX) 0.1 $9.8M NEW 248k 39.66
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Prime Medicine (PRME) 0.1 $9.1M 1.0M 8.86
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Neurogene 0.1 $8.8M NEW 454k 19.38
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Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.1 $8.7M 11M 0.79
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Sana Biotechnology (SANA) 0.1 $8.2M 2.0M 4.08
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Sagimet Biosciences Com Ser A (SGMT) 0.1 $7.9M +78% 1.5M 5.42
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Celcuity (CELC) 0.1 $7.8M 536k 14.57
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Athira Pharma (ATHA) 0.1 $7.7M 3.2M 2.43
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Opthea Sponsored Ads (OPT) 0.1 $7.6M -3% 2.6M 2.95
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Tango Therapeutics (TNGX) 0.1 $7.4M 750k 9.90
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Taysha Gene Therapies Com Shs (TSHA) 0.1 $7.1M +59% 4.0M 1.77
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Hookipa Pharma Inc equity (HOOK) 0.1 $6.6M 8.1M 0.81
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Invitae Corporation Series A Notes 4.5% 3/15/2028 (Principal) 0.1 $6.3M 9.3M 0.68
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Mirum Pharmaceuticals (MIRM) 0.1 $5.6M 191k 29.52
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Xencor (XNCR) 0.1 $5.2M +99% 245k 21.23
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Leap Therapeutics (LPTX) 0.1 $4.9M 1.2M 4.14
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Design Therapeutics (DSGN) 0.0 $4.0M 1.5M 2.65
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Talis Biomedical Corporation (TLIS) 0.0 $3.8M 508k 7.45
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IsoRay (CATX) 0.0 $3.1M 7.6M 0.40
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Vaxcyte (PCVX) 0.0 $3.1M 49k 62.80
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Praxis Precision Medicines I 0.0 $2.9M -93% 132k 22.28
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Century Therapeutics (IPSC) 0.0 $2.6M -30% 798k 3.32
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Mersana Therapeutics (MRSN) 0.0 $2.5M 1.1M 2.32
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Compass Therapeutics (CMPX) 0.0 $2.4M 1.6M 1.56
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Achilles Therapeutics Sponsored Ads (ACHL) 0.0 $1.9M -17% 2.1M 0.89
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Kala Pharmaceuticals (KALA) 0.0 $1.9M 267k 7.00
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Aligos Therapeutics (ALGS) 0.0 $1.4M 2.1M 0.66
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Invitae (NVTA) 0.0 $1.1M 1.8M 0.63
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Pfizer (PFE) 0.0 $1.0M NEW 35k 28.79
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Pmv Pharmaceuticals (PMVP) 0.0 $998k 322k 3.10
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Aadi Bioscience (AADI) 0.0 $509k -74% 252k 2.02
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Protara Therapeutics Com Stk (TARA) 0.0 $374k 200k 1.88
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Cabaletta Bio (CABA) 0.0 $303k -99% 13k 22.70
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Foghorn Therapeutics (FHTX) 0.0 $290k 45k 6.45
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Atreca Cl A Com (BCEL) 0.0 $287k -38% 2.2M 0.13
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Tyra Biosciences (TYRA) 0.0 $147k NEW 11k 13.85
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Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $16k 833k 0.02
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Past Filings by Baker Bros. Advisors

SEC 13F filings are viewable for Baker Bros. Advisors going back to 2010

View all past filings