Hambrecht & Quist Capital Management

Latest statistics and disclosures from Tekla Capital Management's latest quarterly 13F-HR filing:

Tekla Capital Management portfolio companies for December 2015 quarter

Ticker Name Portfolio Weight Change Share Count Price Last Trade
GILD Gilead Sciences 8.55 +4.00% 2331231 101.19 99.53
CELG Celgene Corporation 7.44 -5.00% 1713634 119.76 118.26
BIIB Biogen Idec 5.01 -3.00% 450533 306.35 415.20
VRTX Vertex Pharmaceuticals Incorporated 4.72 +2.00% 1033503 125.83 123.26
Allergan 4.64 +15.00% 409586 312.50 0.00
ALXN Alexion Pharmaceuticals 4.40 -2.00% 636805 190.75 179.76
JNJ Johnson & Johnson 3.51 940988 102.72 98.55
INCY Incyte Corporation 3.46 -9.00% 880461 108.45 88.43
TEVA Teva Pharmaceutical Industries 3.18 -3.00% 1334237 65.64 57.77
REGN Regeneron Pharmaceuticals 3.04 154266 542.87 427.05
ILMN Illumina 3.02 +44.00% 434341 191.95 191.44
BMRN BioMarin Pharmaceutical 2.26 596145 104.76 113.42
PFE Pfizer 2.11 1802291 32.28 33.78
AMGN Amgen 1.89 321640 162.33 153.92
UNH UnitedHealth 1.75 409100 117.64 113.33
Alkermes 1.47 -61.00% 510444 79.38 0.00
MRK Merck & Co 1.30 681097 52.82 56.20
SHPGY Shire 1.28 +247.00% 171813 205.00 0.00
MDVN Medivation 1.17 +224.00% 667300 48.34 127.95
Agilent Technologies Inc C ommon 1.10 +14.00% 728650 41.81 0.00
HCA HOLDINGS 1.10 +84.00% 448488 67.63 0.00
Mylan Nv 1.04 -75.00% 531252 54.07 0.00
HUM Humana 0.84 -31.00% 129300 178.51 160.10
ACAD ACADIA Pharmaceuticals 0.82 +13.00% 637500 35.65 43.70
VTR Ventas 0.76 369266 56.43 69.27
MOH Molina Healthcare 0.76 347901 60.13 61.05
Physicians Realty Trust 0.75 1230772 16.86 0.00
Puma Biotechnology Inc Common Stock 0.74 +85.00% 260200 78.40 0.00
IBB iShares NASDAQ Biotechnology Index 0.71 57670 338.32 341.41
MPW Medical Properties Trust 0.65 -4.00% 1564060 11.51 13.91
NBIX Neurocrine Biosciences 0.64 -17.00% 311460 56.57 40.28
Endo International 0.64 -10.00% 286348 61.22 0.00
NVO Novo Nordisk A/S 0.62 294600 58.08 46.07
MCK McKesson Corporation 0.59 +22.00% 82862 197.23 221.98
Horizon Pharma 0.59 +130.00% 749900 21.67 0.00
STJ St. Jude Medical 0.57 +58.00% 255810 61.77 66.17
MDCO Medicines Company 0.54 -35.00% 401970 37.34 27.02
IPXL Impax Laboratories 0.53 344683 42.76 42.51
UTHR United Therapeutics Corporation 0.53 -49.00% 93100 156.61 161.87
OHI Omega Healthcare Investors 0.52 413116 34.98 38.61
Paratek Pharmaceuticals 0.52 762581 18.97 0.00
BMY Bristol Myers Squibb 0.51 -71.00% 202600 68.79 66.08
Corsicanto Ltd conv bnd 0.49 14700000 0.91 0.00
SNY Sanofi-Aventis SA 0.47 NEW 305000 42.65 47.19
ALNY Alnylam Pharmaceuticals 0.47 -55.00% 137495 94.14 111.05
Anacor Pharmaceuticals In 0.45 -15.00% 110038 112.97 0.00
Baxalta Incorporated 0.45 319600 39.03 0.00
BAX Baxter International 0.44 319600 38.15 67.92
TMO Thermo Fisher Scientific 0.44 86395 141.85 127.98
CPHD Cepheid 0.44 NEW 333590 36.53 55.12
Welltower Inc 6.50% pfd prepet 0.44 200000 60.91 0.00
GSK GlaxoSmithKline 0.42 285000 40.35 45.62
SYK Stryker Corporation 0.42 123940 92.94 90.61
ALR Alere 0.42 297901 39.09 47.27
Ardelyx 0.42 639370 18.12 0.00
ZMH Zimmer Holdings 0.38 102300 102.59 116.78
LTC LTC Properties 0.37 236618 43.14 42.07
Intra Cellular Therapies 0.37 +25.00% 187800 53.79 0.00
SNH Senior Housing Properties Trust 0.36 670504 14.84 21.25
Ultragenyx Pharmaceutical 0.36 88400 112.18 0.00
IDXX IDEXX Laboratories 0.35 132352 72.92 149.73
Medtronic 0.35 -57.00% 124344 76.92 0.00
Natera 0.35 +8.00% 882358 10.80 0.00
SBRA Sabra Health Care REIT 0.33 456190 20.23 30.80
Icon 0.32 +59.00% 114900 77.70 0.00
Cepheid conv 0.32 NEW 10000000 0.89 0.00
Pieris Pharmaceuticals 0.32 3848191 2.29 0.00
Aegerion Pharmaceuticals 2% Du cvbond 0.31 13000000 0.66 0.00
UHS Universal Health Services 0.30 NEW 70300 119.49 113.94
NVS Novartis AG 0.29 92700 86.04 96.03
CYH Community Health Systems 0.29 +45.00% 304472 26.53 49.70
CNC Centene Corporation 0.29 120000 65.81 63.33
Juno Therapeutics 0.29 182000 43.97 0.00
LLY Eli Lilly & Co. 0.26 85667 84.26 68.81
WCG WellCare Health Plans 0.25 88652 78.20 88.95
Cytomx Therapeutics 0.25 NEW 328059 20.87 0.00
Merrimack Pharmaceuticals In 0.24 853787 7.90 0.00
Karyopharm Therapeutics 0.24 -59.00% 500324 13.25 0.00
Dynavax Technologies 0.24 275000 24.16 0.00
Retrophin 0.23 NEW 329949 19.29 0.00
Cellectis S A sponsored ads 0.23 +30.00% 207250 31.03 0.00
Auris Med Hldg Ag 0.22 -39.00% 1268263 4.89 0.00
EXEL Exelixis 0.21 NEW 1023877 5.64 3.00
FLML Flamel Technologies S.A. 0.21 NEW 474288 12.21 16.43
Accelr8 Technology 0.21 +82.00% 264625 21.49 0.00
Heron Therapeutics 0.21 219000 26.70 0.00
Sage Therapeutics 0.21 -45.00% 97800 58.30 0.00
AKRX Akorn 0.20 -82.00% 145235 37.31 47.03
ELGX Endologix 0.20 551000 9.90 15.20
Perrigo Company 0.20 +97.00% 37300 144.69 0.00
HR Healthcare Realty Trust Incorporated 0.19 187224 28.32 26.23
Foamix Pharmaceuticals Ltd shs 0.19 +6.00% 652145 8.11 0.00
Supernus Pharmaceuticals note 7.500 5/0 0.19 2000000 2.68 0.00
Allergan Plc pfd conv ser a 0.19 5000 1030.20 0.00
Tenet Healthcare Corporation stock 0.18 164500 30.30 0.00
Sagent Pharmaceuticals 0.17 -30.00% 286650 15.91 0.00
Mallinckrodt Pub 0.17 -14.00% 61900 74.64 0.00
Inotek Pharmaceuticals 0.17 425000 11.33 0.00
Arca Biopharma 0.14 811227 4.65 0.00
DEPO DepoMed 0.13 200000 18.13 24.18
HALO Halozyme Therapeutics 0.13 NEW 200000 17.33 15.18
Alliqua 0.13 1650000 2.14 0.00
Adaptimmune Therapeutics 0.13 +5.00% 296934 12.06 0.00
NVAX Novavax 0.11 NEW 358000 8.39 9.03
Bluebird Bio 0.11 -69.00% 49345 64.22 0.00
Uniqure Nv shs 0.11 -14.00% 175500 16.54 0.00
Flex Pharma 0.11 232600 12.45 0.00
MDRX Allscripts Healthcare Solutions 0.10 -90.00% 173600 15.38 11.88
Insmed 0.10 NEW 156600 18.15 0.00
Grifols S A Sponsored Adr R 0.10 83000 32.40 0.00
Lexicon Pharmaceuticals 0.10 -72.00% 197641 13.31 0.00
Cynapsus Therapeutics 0.10 +265.00% 180407 15.44 0.00
Kite Pharma 0.09 +550.00% 41000 61.61 0.00
Forward Pharma A/s 0.09 +3.00% 136547 19.00 0.00
Dbv Technologies S A 0.09 65600 36.31 0.00
Care Cap Properties 0.09 84316 30.58 0.00
MNTA Momenta Pharmaceuticals 0.08 153700 14.84 14.37
Gw Pharmaceuticals Plc ads 0.08 -77.00% 30000 69.43 0.00
Esperion Therapeutics 0.08 -50.00% 102800 22.26 0.00
Merrimack Pharmaceuticals In note 4.500% 7/1 0.08 1485000 1.48 0.00
Affimed Therapeutics B V 0.08 +28.00% 294213 7.12 0.00
Tetraphase Pharmaceuticals 0.07 192322 10.03 0.00
CLDX Celldex Therapeutics 0.06 -68.00% 105800 15.68 29.43
Nevro 0.06 NEW 25000 67.52 0.00
Galapagos Nv-spon 0.05 20000 62.90 0.00
Bellicum Pharma 0.04 60000 20.27 0.00
GNMK GenMark Diagnostics 0.03 -56.00% 93349 7.76 11.94
Cidara Therapeutics Inc Common Stock Usd 0.0001 0.03 +5.00% 52500 17.16 0.00
Chimerix 0.02 47800 8.95 0.00
Xencor 0.01 20000 14.60 0.00
Abbvie 0.00 -99.00% 156 57.69 0.00
Zafgen 0.00 13307 6.31 0.00
Rmr Group Inc cl a 0.00 NEW 7441 14.38 0.00
Gilead Sciences 0.00 NEW 278 97.12 0.00