Is ISIS a good stock to own? Find out who bought ISIS Pharmaceuticals, who sold ISIS Pharmaceuticals (ISIS) stock, and who holds a large position in ISIS Pharmaceuticals.

• Artisan Partners Limited Partnership owns 8.59M shares worth $145.45M
• BB Biotech AG owns 7.69M shares worth $130.34M
• ClearBridge Advisors owns 6.30M shares worth $106.79M
• Vanguard owns 5.34M shares worth $90.54M
• Columbia Wanger Asset Management owns 5.08M shares worth $71.52M
• STATE STREET CORPORATION owns 2.88M shares worth $48.71M
• Waddell & Reed Financial owns 2.81M shares worth $47.53M
• T. Rowe Price Associates owns 2.25M shares worth $38.08M
• Tocqueville Asset Management owns 2.10M shares worth $35.50M
• Gail Mannix owns 1.92M shares worth $32.58M
• Jennison Associates owns 1.85M shares worth $31.26M
• Allianz Asset Management AG owns 1.12M shares worth $18.89M
• Visium Asset Management owns 1.04M shares worth $17.64M
• GRANAHAN INVESTMENT MANAGEMENT INC/MA owns 910089 shares worth $15.42M
• Franklin Resources owns 888970 shares worth $15.06M
• Dowling & Yahnke, LLC" owns 775798 shares worth $13.14M
• Stifel, Nicolaus & Company, Incorporated owns 767550 shares worth $9.21M
• Millennium Management owns 703751 shares worth $11.92M
• PanAgora Asset Management owns 638931 shares worth $6.68M
• Cupps Capital Management owns 583493 shares worth $8.21M
• BVF owns 577100 shares worth $9.78M
• GOLDMAN SACHS owns 574123 shares worth $9.73M
• Perella Weinberg Partners Capital Management owns 519100 shares worth $7.30M
• William Harris Investors owns 467334 shares worth $4.88M
• PointState Capital owns 455472 shares worth $6.41M
• TIAA-CREF Investment Management owns 443702 shares worth $6.24M

• Johnston Asset Management sold on June 30, 2011
• Manalapan Oracle Capital Management sold on June 30, 2011
• Renaissance Technologies sold on March 31, 2011
• FMR sold on Dec. 31, 2010

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