EcoR1 Capital
Latest statistics and disclosures from EcoR1 Capital's latest quarterly 13F-HR filing:
- Top 5 stock holdings are ZYME, ANAB, JAZZ, CRNX, CNTA, and represent 70.53% of EcoR1 Capital's stock portfolio.
- Added to shares of these 10 stocks: CNTA (+$64M), CGON (+$44M), ZBIO (+$29M), GPCR (+$23M), PCVX (+$21M), VYGR (+$13M), MNKD (+$9.4M), EOLS, IBIO, MREO.
- Started 9 new stock positions in EOLS, GPCR, CGON, IBIO, PCVX, MNKD, CAMP, ZBIO, MREO.
- Reduced shares in these 10 stocks: QURE (-$233M), TNGX (-$89M), APLS (-$78M), XNCR (-$43M), MDGL (-$34M), RNA (-$33M), IMNM (-$26M), , MTSR (-$14M), PRME (-$8.6M).
- Sold out of its positions in APLS, RNA, CMPS, KURA, MDGL, MTSR, PEPG, PRME, TNGX, ALKS. QURE.
- EcoR1 Capital was a net seller of stock by $-372M.
- EcoR1 Capital has $2.2B in assets under management (AUM), dropping by 5.77%.
- Central Index Key (CIK): 0001587114
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Portfolio Holdings for EcoR1 Capital
EcoR1 Capital holds 28 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Zymeworks Del (ZYME) | 27.4 | $605M | 23M | 26.33 |
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| Anaptysbio Inc Common (ANAB) | 17.3 | $382M | 7.9M | 48.48 |
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| Jazz Pharmaceuticals Shs Usd (JAZZ) | 13.2 | $290M | 1.7M | 170.00 |
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| Crinetics Pharmaceuticals In (CRNX) | 9.1 | $200M | 4.3M | 46.55 |
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| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 3.5 | $78M | +466% | 3.1M | 25.01 |
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| Crispr Therapeutics Namen Akt (CRSP) | 3.3 | $73M | 1.4M | 52.44 |
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| Mbx Biosciences (MBX) | 3.0 | $67M | 2.1M | 31.54 |
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| Immunome (IMNM) | 2.8 | $61M | -30% | 2.9M | 21.48 |
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| Oric Pharmaceuticals (ORIC) | 2.5 | $55M | 6.7M | 8.18 |
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| Galapagos Nv Spon Adr (GLPG) | 2.5 | $55M | 1.7M | 32.70 |
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| Xencor (XNCR) | 2.3 | $51M | -45% | 3.3M | 15.31 |
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| Cg Oncology (CGON) | 2.0 | $44M | NEW | 1.1M | 41.52 |
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| Bridgebio Oncology Therapeut Com New (BBOT) | 1.6 | $35M | 2.8M | 12.52 |
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| Eton Pharmaceuticals (ETON) | 1.6 | $34M | 2.0M | 16.91 |
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| Zenas Biopharma (ZBIO) | 1.3 | $29M | NEW | 790k | 36.31 |
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| Neurogene (NGNE) | 1.2 | $26M | 1.3M | 20.60 |
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| Structure Therapeutics Sponsored Ads (GPCR) | 1.1 | $23M | NEW | 334k | 69.55 |
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| Vaxcyte (PCVX) | 0.9 | $21M | NEW | 450k | 46.14 |
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| Aquestive Therapeutics (AQST) | 0.8 | $17M | 2.6M | 6.46 |
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| Voyager Therapeutics (VYGR) | 0.7 | $16M | +497% | 4.0M | 3.93 |
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| Atara Biotherapeutics Com New (ATRA) | 0.5 | $10M | 573k | 18.09 |
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| Mannkind Corp Com New (MNKD) | 0.4 | $9.4M | NEW | 1.7M | 5.67 |
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| Nuvation Bio *w Exp 02/10/202 (NUVB.WS) | 0.4 | $8.6M | 963k | 8.96 |
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| Evolus (EOLS) | 0.2 | $4.5M | NEW | 675k | 6.65 |
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| Ibio Com New (IBIO) | 0.2 | $4.3M | NEW | 2.2M | 1.93 |
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| Mereo Biopharma Group Spon Ads (MREO) | 0.1 | $3.3M | NEW | 7.9M | 0.42 |
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| Camp4 Therapeutics Corp (CAMP) | 0.1 | $2.0M | NEW | 325k | 6.13 |
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| Surrozen *w Exp 08/01/203 (SRZNW) | 0.0 | $100k | -93% | 4.4k | 22.60 |
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Past Filings by EcoR1 Capital
SEC 13F filings are viewable for EcoR1 Capital going back to 2014
- EcoR1 Capital 2025 Q4 filed Feb. 17, 2026
- EcoR1 Capital 2025 Q3 filed Nov. 14, 2025
- EcoR1 Capital 2025 Q2 filed Aug. 14, 2025
- EcoR1 Capital 2025 Q1 filed May 15, 2025
- EcoR1 Capital 2024 Q4 filed Feb. 14, 2025
- EcoR1 Capital 2024 Q3 filed Nov. 14, 2024
- EcoR1 Capital 2024 Q2 filed Aug. 14, 2024
- EcoR1 Capital 2024 Q1 filed May 15, 2024
- EcoR1 Capital 2023 Q4 filed Feb. 14, 2024
- EcoR1 Capital 2023 Q3 filed Nov. 14, 2023
- EcoR1 Capital 2023 Q2 filed Aug. 14, 2023
- EcoR1 Capital 2023 Q1 filed May 15, 2023
- EcoR1 Capital 2022 Q4 filed Feb. 14, 2023
- EcoR1 Capital 2022 Q3 filed Nov. 14, 2022
- EcoR1 Capital 2022 Q2 filed Aug. 15, 2022
- EcoR1 Capital 2022 Q1 filed May 16, 2022