Frazier Life Sciences Management

Latest statistics and disclosures from Frazier Life Sciences Management's latest quarterly 13F-HR filing:

  • Top 5 stock holdings are MIRM, NAMS, VRNA, BBIO, ARQT, and represent 51.54% of Frazier Life Sciences Management's stock portfolio.
  • Added to shares of these 10 stocks: ABVX (+$32M), CYTK (+$19M), DYN (+$15M), ACAD (+$13M), ASMB (+$12M), MBX (+$12M), ZLAB (+$11M), VALN (+$10M), ENGN (+$7.9M), ADVM.
  • Started 4 new stock positions in ENGN, ASMB, ABVX, ACAD.
  • Reduced shares in these 10 stocks: Hillevax (-$21M), CGON (-$20M), TVTX (-$15M), IRON (-$14M), TARS (-$14M), COGT (-$13M), ORIC (-$11M), ALKS (-$9.0M), ORKA (-$6.5M), JBIO.
  • Sold out of its positions in CGON, COGT, ELEV, Hillevax, ORIC, ORKA.
  • Frazier Life Sciences Management was a net buyer of stock by $14M.
  • Frazier Life Sciences Management has $3.3B in assets under management (AUM), dropping by 33.46%.
  • Central Index Key (CIK): 0001892134

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Portfolio Holdings for Frazier Life Sciences Management

Frazier Life Sciences Management holds 47 positions in its portfolio as reported in the September 2025 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Mirum Pharmaceuticals (MIRM) 14.9 $498M 6.8M 73.31
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Newamsterdam Pharma Company Ordinary Shares (NAMS) 14.2 $475M 17M 28.44
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Verona Pharma Sponsored Ads (VRNA) 10.8 $361M 3.4M 106.71
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Bridgebio Pharma (BBIO) 6.0 $200M 3.8M 51.94
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Arcutis Biotherapeutics (ARQT) 5.6 $186M 9.9M 18.85
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Phathom Pharmaceuticals (PHAT) 4.4 $147M 13M 11.77
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Krystal Biotech (KRYS) 3.6 $122M 689k 176.53
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Maze Therapeatics (MAZE) 3.5 $118M 4.6M 25.93
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Mbx Biosciences (MBX) 3.5 $116M +11% 6.7M 17.50
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Disc Medicine (IRON) 2.8 $95M -13% 1.4M 66.08
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Trevi Therapeutics (TRVI) 2.8 $94M 10M 9.15
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Tarsus Pharmaceuticals (TARS) 2.1 $69M -16% 1.2M 59.43
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Kalvista Pharmaceuticals (KALV) 1.8 $61M +3% 5.0M 12.18
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Zai Lab Adr (ZLAB) 1.7 $55M +24% 1.6M 33.89
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Agios Pharmaceuticals (AGIO) 1.5 $51M 1.3M 40.14
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Erasca (ERAS) 1.5 $50M 23M 2.18
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Cytokinetics Com New (CYTK) 1.5 $49M +60% 890k 54.96
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Revolution Medicines (RVMD) 1.4 $47M 998k 46.70
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Palvella Therapeutics Inc Ne (PVLA) 1.4 $45M 722k 62.69
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Savara (SVRA) 1.2 $41M 12M 3.57
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Dyne Therapeutics (DYN) 1.0 $34M +80% 2.7M 12.65
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Abivax Sa Sponsored Ads (ABVX) 1.0 $32M NEW 378k 84.90
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Aura Biosciences (AURA) 0.9 $32M 5.1M 6.18
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Ultragenyx Pharmaceutical (RARE) 0.9 $30M 984k 30.08
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Lexeo Therapeutics (LXEO) 0.9 $29M 4.4M 6.64
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Valneva Se Sponsored Ads (VALN) 0.8 $28M +57% 2.3M 12.20
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Avidity Biosciences Ord (RNA) 0.8 $27M 625k 43.57
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Ascendis Pharma A/s Sponsored Adr (ASND) 0.8 $27M 133k 198.81
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Alkermes SHS (ALKS) 0.6 $21M -29% 701k 30.00
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Mereo Biopharma Group Spon Ads (MREO) 0.6 $19M 9.4M 2.06
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Akero Therapeutics (AKRO) 0.5 $17M 367k 47.48
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Vaxcyte (PCVX) 0.5 $17M 474k 36.02
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Evolus (EOLS) 0.5 $16M +8% 2.6M 6.14
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Design Therapeutics (DSGN) 0.4 $15M 2.0M 7.53
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Immunocore Hldgs Ads (IMCR) 0.4 $14M 385k 36.33
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ACADIA Pharmaceuticals (ACAD) 0.4 $13M NEW 614k 21.34
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Jade Biosciences Com New (JBIO) 0.4 $12M -20% 1.4M 8.63
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Assembly Biosciences Com New (ASMB) 0.3 $12M NEW 456k 25.60
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Adverum Biotechnologies Com New (ADVM) 0.3 $9.4M +94% 2.1M 4.53
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Travere Therapeutics (TVTX) 0.3 $9.4M -60% 392k 23.90
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Newamsterdam Pharma Company *w Exp 99/99/999 (NAMSW) 0.3 $8.6M 500k 17.11
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Engene Holdings (ENGN) 0.2 $7.9M NEW 1.2M 6.83
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Autolus Therapeutics Spon Ads (AUTL) 0.2 $7.5M 4.6M 1.63
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Macrogenics (MGNX) 0.2 $5.3M 3.2M 1.68
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Silence Therapeutics Ads (SLN) 0.2 $5.0M 970k 5.19
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Allogene Therapeutics (ALLO) 0.1 $4.8M 3.9M 1.24
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Crescent Biopharma (CBIO) 0.1 $3.2M -39% 273k 11.89
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Past Filings by Frazier Life Sciences Management

SEC 13F filings are viewable for Frazier Life Sciences Management going back to 2022