Ikarian Capital
Latest statistics and disclosures from Ikarian Capital's latest quarterly 13F-HR filing:
- Top 5 stock holdings are UTHR, XBI, GMAB, BMY, ABVX, and represent 28.94% of Ikarian Capital's stock portfolio.
- Added to shares of these 10 stocks: UTHR (+$89M), XBI (+$75M), GMAB (+$53M), BMY (+$36M), ABVX (+$33M), PTCT (+$30M), IONS (+$28M), RAPT (+$20M), SRRK (+$19M), APLS (+$17M).
- Started 48 new stock positions in UPB, Bridgebio Oncology Therapeut, CMPS, LQDA, Jazz Pharmaceuticals Plc cmn, SNDX, PRME, ZURA, Veru, AGIO.
- Reduced shares in these 10 stocks: CDTX (-$97M), RARE (-$23M), PRAX (-$21M), COGT (-$19M), , Uniqure Nv call (-$15M), VRNA (-$14M), APGE (-$14M), SRPT (-$12M), VKTX (-$12M).
- Sold out of its positions in ALNY, TKNO, APGE, RCUS, BIIB, Chemomab Therapeutics, ELDN, GERN, HOOK, INBX. IBB, KYMR, NUVB, ORKA, SGMT, SPRB, TECX, TRML, VERA, VRNA, VERU, VIGL, PRTA.
- Ikarian Capital was a net buyer of stock by $315M.
- Ikarian Capital has $990M in assets under management (AUM), dropping by 90.23%.
- Central Index Key (CIK): 0001778253
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Portfolio Holdings for Ikarian Capital
Ikarian Capital holds 139 positions in its portfolio as reported in the September 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| United Therapeutics Corporation Put Option (UTHR) | 9.0 | $89M | NEW | 212k | 419.21 |
|
| Spdr Series Trust S&p Biotech Put Option (XBI) | 7.6 | $75M | NEW | 750k | 100.20 |
|
| Genmab A/s Sponsored Ads (GMAB) | 5.4 | $53M | NEW | 175k | 302.98 |
|
| Bristol Myers Squibb Put Option (BMY) | 3.6 | $36M | NEW | 800k | 45.10 |
|
| Abivax Sa Sponsored Ads (ABVX) | 3.4 | $33M | NEW | 396k | 84.36 |
|
| Uniqure Nv Call Call Option | 3.2 | $31M | -33% | 536k | 58.37 |
|
| Insmed Com Par $.01 (INSM) | 3.1 | $31M | +30% | 214k | 144.01 |
|
| Ptc Therapeutics I (PTCT) | 3.1 | $30M | NEW | 494k | 61.37 |
|
| Ionis Pharmaceuticals (IONS) | 2.8 | $28M | NEW | 429k | 65.42 |
|
| Cidara Therapeutics Com New (CDTX) | 2.7 | $27M | -78% | 278k | 95.76 |
|
| Scholar Rock Hldg Corp Put Option (SRRK) | 2.5 | $25M | +340% | 658k | 37.24 |
|
| Rapt Therapeutics Com New (RAPT) | 2.1 | $20M | NEW | 790k | 25.79 |
|
| Maze Therapeatics (MAZE) | 1.9 | $19M | +181% | 741k | 25.93 |
|
| Soleno Therapeutics (SLNO) | 1.9 | $19M | -29% | 282k | 67.60 |
|
| Cytokinetics Com New (CYTK) | 1.9 | $18M | -13% | 334k | 54.96 |
|
| Apellis Pharmaceuticals (APLS) | 1.9 | $18M | +979% | 810k | 22.63 |
|
| Crinetics Pharmaceuticals In (CRNX) | 1.6 | $16M | -10% | 389k | 41.65 |
|
| Harrow Health Call Option (HROW) | 1.4 | $14M | NEW | 290k | 48.18 |
|
| Dianthus Therapeutics (DNTH) | 1.4 | $14M | NEW | 346k | 39.35 |
|
| Biohaven Call Call Option | 1.2 | $12M | +165% | 796k | 15.01 |
|
| Fulcrum Therapeutics (FULC) | 1.2 | $12M | +33% | 1.3M | 9.20 |
|
| Akero Therapeutics (AKRO) | 1.2 | $12M | -6% | 249k | 47.48 |
|
| Vaxcyte (PCVX) | 1.2 | $12M | +2% | 319k | 36.02 |
|
| Anaptysbio Inc Common (ANAB) | 1.1 | $11M | +2266% | 371k | 30.62 |
|
| Agios Pharmaceuticals (AGIO) | 1.1 | $11M | NEW | 277k | 40.14 |
|
| Cytomx Therapeutics (CTMX) | 1.1 | $11M | NEW | 3.4M | 3.19 |
|
| Moonlake Immunotherapeutics Class A Ord (MLTX) | 1.1 | $11M | +418% | 1.5M | 7.17 |
|
| Jazz Pharmaceuticals Shs Usd (JAZZ) | 1.0 | $10M | +94% | 78k | 131.80 |
|
| Cg Oncology (CGON) | 1.0 | $10M | +60% | 250k | 40.28 |
|
| Travere Therapeutics (TVTX) | 1.0 | $9.7M | NEW | 405k | 23.90 |
|
| Jazz Pharmaceuticals Call Call Option | 0.9 | $9.3M | NEW | 71k | 131.80 |
|
| Zura Bio Class A Ord Shs (ZURA) | 0.9 | $9.2M | NEW | 2.1M | 4.33 |
|
| Mestera Put Option (MTSR) | 0.9 | $9.0M | +122% | 172k | 52.33 |
|
| Novo-nordisk A S Adr Call Option (NVO) | 0.8 | $8.3M | NEW | 150k | 55.49 |
|
| Mbx Biosciences (MBX) | 0.8 | $7.8M | NEW | 448k | 17.50 |
|
| Centessa Pharmaceuticals Sponsored Ads Call Option (CNTA) | 0.8 | $7.5M | +53% | 308k | 24.25 |
|
| Tenax Therapeutics Com New (TENX) | 0.7 | $7.4M | NEW | 968k | 7.61 |
|
| Praxis Precision Medicines I Com New (PRAX) | 0.7 | $6.8M | -75% | 129k | 53.00 |
|
| Kodiak Sciences (KOD) | 0.7 | $6.8M | -30% | 414k | 16.37 |
|
| Tg Therapeutics (TGTX) | 0.6 | $6.3M | -16% | 175k | 36.12 |
|
| Alpha Cognition Com New (ACOG) | 0.6 | $6.2M | +3% | 946k | 6.51 |
|
| Silverback Therapeutics Call Option (SPRY) | 0.6 | $5.7M | NEW | 562k | 10.05 |
|
| Miragen Therapeutics (VRDN) | 0.5 | $5.3M | -47% | 246k | 21.58 |
|
| Pharvaris N V (PHVS) | 0.5 | $5.2M | NEW | 210k | 24.95 |
|
| Syndax Pharmaceuticals (SNDX) | 0.5 | $5.1M | NEW | 334k | 15.38 |
|
| Kalvista Pharmaceuticals Call Option (KALV) | 0.5 | $4.9M | -33% | 400k | 12.18 |
|
| Delcath Sys Com New (DCTH) | 0.5 | $4.6M | +33% | 431k | 10.75 |
|
| Structure Therapeutics Sponsored Ads (GPCR) | 0.5 | $4.6M | -10% | 163k | 28.00 |
|
| Liquidia Corporation Com New Call Option (LQDA) | 0.5 | $4.5M | NEW | 200k | 22.74 |
|
| Forte Biosciences Com New (FBRX) | 0.5 | $4.5M | -37% | 300k | 15.00 |
|
| Revolution Medicines Call Option (RVMD) | 0.4 | $4.4M | NEW | 95k | 46.70 |
|
| Arcturus Therapeutics Hldg I (ARCT) | 0.4 | $4.4M | +35% | 238k | 18.43 |
|
| Tarsus Pharmaceuticals (TARS) | 0.4 | $4.4M | -62% | 74k | 59.43 |
|
| Krystal Biotech (KRYS) | 0.4 | $4.3M | NEW | 24k | 176.53 |
|
| Argenx Se Sponsored Adr (ARGX) | 0.4 | $4.3M | NEW | 5.9k | 724.19 |
|
| Ventyx Biosciences (VTYX) | 0.4 | $4.1M | +35% | 1.3M | 3.11 |
|
| Palvella Therapeutics Inc Ne (PVLA) | 0.4 | $4.1M | NEW | 65k | 62.69 |
|
| Teva Pharmaceutical Inds Sponsored Ads Call Option (TEVA) | 0.4 | $4.0M | 200k | 20.20 |
|
|
| Solid Biosciences Com New (SLDB) | 0.4 | $4.0M | NEW | 645k | 6.17 |
|
| Altimmune Com New Call Option (ALT) | 0.4 | $3.8M | +20% | 1.0M | 3.77 |
|
| Lexeo Therapeutics (LXEO) | 0.4 | $3.8M | +3% | 568k | 6.64 |
|
| Direxion Shs Etf Tr Daily S&p Biotec | 0.4 | $3.7M | NEW | 92k | 40.44 |
|
| Relmada Therapeutics (RLMD) | 0.4 | $3.7M | +4476% | 1.8M | 2.01 |
|
| Prime Medicine (PRME) | 0.4 | $3.6M | NEW | 650k | 5.54 |
|
| Uniqure Nv SHS (QURE) | 0.3 | $3.4M | -51% | 59k | 58.37 |
|
| Vir Biotechnology (VIR) | 0.3 | $3.4M | -44% | 593k | 5.71 |
|
| Capricor Therapeutics Com New (CAPR) | 0.3 | $3.4M | -77% | 465k | 7.21 |
|
| Newamsterdam Pharma Company Ordinary Shares (NAMS) | 0.3 | $3.0M | -48% | 107k | 28.44 |
|
| Upstream Bio (UPB) | 0.3 | $3.0M | NEW | 161k | 18.81 |
|
| Fractyl Health (GUTS) | 0.3 | $2.9M | NEW | 1.8M | 1.59 |
|
| Bridgebio Oncology Therapeut Com New | 0.3 | $2.8M | NEW | 245k | 11.58 |
|
| Ultragenyx Pharmaceutical Put Option (RARE) | 0.3 | $2.8M | -89% | 93k | 30.08 |
|
| Bridgebio Pharma (BBIO) | 0.3 | $2.7M | NEW | 52k | 51.94 |
|
| Sarepta Therapeutics Call Option (SRPT) | 0.3 | $2.6M | -82% | 137k | 19.27 |
|
| Pepgen (PEPG) | 0.3 | $2.5M | +257% | 536k | 4.62 |
|
| Neuronetics (STIM) | 0.2 | $2.5M | -17% | 906k | 2.73 |
|
| Relay Therapeutics (RLAY) | 0.2 | $2.4M | -37% | 467k | 5.22 |
|
| Adma Biologics (ADMA) | 0.2 | $2.3M | NEW | 160k | 14.66 |
|
| Catalyst Pharmaceutical Partners (CPRX) | 0.2 | $2.3M | -44% | 116k | 19.70 |
|
| Compass Pathways Sponsored Ads Call Option (CMPS) | 0.2 | $2.3M | NEW | 400k | 5.73 |
|
| Adagio Therapeutics (IVVD) | 0.2 | $2.3M | NEW | 2.1M | 1.10 |
|
| Alector (ALEC) | 0.2 | $2.2M | -15% | 760k | 2.96 |
|
| Vistagen Therapeutics Ord (VTGN) | 0.2 | $2.2M | +3% | 621k | 3.55 |
|
| Avalo Therapeutics Com New (AVTX) | 0.2 | $2.0M | +352% | 160k | 12.71 |
|
| Arvinas Ord (ARVN) | 0.2 | $1.9M | -73% | 226k | 8.52 |
|
| Proqr Thrapeutics N V Shs Euro (PRQR) | 0.2 | $1.9M | +2% | 892k | 2.13 |
|
| Larimar Therapeutics Call Option (LRMR) | 0.2 | $1.8M | NEW | 548k | 3.23 |
|
| Pelthos Therapeutics Com Shs | 0.2 | $1.7M | NEW | 63k | 28.00 |
|
| Cumberland Pharmaceuticals (CPIX) | 0.2 | $1.7M | -6% | 556k | 3.12 |
|
| Dyne Therapeutics (DYN) | 0.1 | $1.4M | -68% | 114k | 12.65 |
|
| Ovid Therapeutics (OVID) | 0.1 | $1.4M | NEW | 1.1M | 1.30 |
|
| Janux Therapeutics (JANX) | 0.1 | $1.3M | -57% | 55k | 24.44 |
|
| Silence Therapeutics Ads (SLN) | 0.1 | $1.3M | +3% | 901k | 1.45 |
|
| Zymeworks Del (ZYME) | 0.1 | $1.2M | +191% | 73k | 17.08 |
|
| Terns Pharmaceuticals (TERN) | 0.1 | $1.2M | +180% | 164k | 7.51 |
|
| Inflarx Nv (IFRX) | 0.1 | $968k | +2% | 722k | 1.34 |
|
| Bright Minds Biosciences Com New (DRUG) | 0.1 | $936k | -76% | 15k | 60.66 |
|
| Sangamo Biosciences (SGMO) | 0.1 | $872k | +2% | 1.3M | 0.67 |
|
| Cybin Com New (CYBN) | 0.1 | $827k | 141k | 5.89 |
|
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| Immunic (IMUX) | 0.1 | $806k | 914k | 0.88 |
|
|
| Tvardi Therapeutics Call Option (TVRD) | 0.1 | $740k | NEW | 19k | 38.97 |
|
| Mind Medicine Mindmed Com New (MNMD) | 0.1 | $739k | 63k | 11.79 |
|
|
| Lyell Immunopharma Com New (LYEL) | 0.1 | $711k | 44k | 16.24 |
|
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| Wave Life Sciences SHS (WVE) | 0.1 | $702k | -40% | 96k | 7.32 |
|
| Corbus Pharmaceuticals Hldgs Com New Call Option (CRBP) | 0.1 | $693k | NEW | 55k | 12.65 |
|
| Sonnet Biotherapeutc Hldng I Com New (SONN) | 0.1 | $687k | NEW | 150k | 4.58 |
|
| Io Biotech (IOBT) | 0.1 | $554k | NEW | 1.5M | 0.36 |
|
| Veru Com New | 0.1 | $542k | NEW | 143k | 3.80 |
|
| Ibio Com New (IBIO) | 0.1 | $511k | +2% | 617k | 0.83 |
|
| Equillium (EQ) | 0.0 | $475k | NEW | 332k | 1.43 |
|
| Acumen Pharmaceuticals (ABOS) | 0.0 | $455k | 266k | 1.71 |
|
|
| Alto Neuroscience Com Shs (ANRO) | 0.0 | $442k | 110k | 4.02 |
|
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| Immatics SHS (IMTX) | 0.0 | $421k | 49k | 8.52 |
|
|
| Kezar Life Sciences Com New (KZR) | 0.0 | $417k | 107k | 3.90 |
|
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| Anebulo Pharmaceuticals (ANEB) | 0.0 | $394k | 158k | 2.50 |
|
|
| Evaxion As Sponsored Ads (EVAX) | 0.0 | $301k | 80k | 3.76 |
|
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| Viking Therapeutics (VKTX) | 0.0 | $263k | -97% | 10k | 26.28 |
|
| Voyager Therapeutics (VYGR) | 0.0 | $260k | 56k | 4.67 |
|
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| Lexicon Pharmaceuticals Com New (LXRX) | 0.0 | $238k | 177k | 1.35 |
|
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| Nyxoah S A SHS (NYXH) | 0.0 | $233k | 51k | 4.60 |
|
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| Cartesian Therapeutics Com New (RNAC) | 0.0 | $227k | 22k | 10.22 |
|
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| Sensei Biotherapeutics Com New (SNSE) | 0.0 | $213k | 23k | 9.45 |
|
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| Biomx Com New (PHGE) | 0.0 | $206k | -55% | 393k | 0.53 |
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| Karyopharm Therapeutics Com New (KPTI) | 0.0 | $178k | 27k | 6.54 |
|
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| Cogent Biosciences (COGT) | 0.0 | $162k | -99% | 11k | 14.36 |
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| Airsculpt Technologies (AIRS) | 0.0 | $144k | 18k | 8.02 |
|
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| Chemomab Therapeutics Sponsored Ads (CMMB) | 0.0 | $140k | NEW | 53k | 2.63 |
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| Lyra Therapeutics Com New (LYRA) | 0.0 | $140k | 21k | 6.59 |
|
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| Pmv Pharmaceuticals (PMVP) | 0.0 | $137k | NEW | 98k | 1.40 |
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| Macrogenics (MGNX) | 0.0 | $135k | 80k | 1.68 |
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| Spruce Biosciences Com New | 0.0 | $119k | NEW | 13k | 8.95 |
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| Aethlon Med Com New (AEMD) | 0.0 | $115k | 154k | 0.75 |
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| Vyne Therapeutics (VYNE) | 0.0 | $97k | 290k | 0.34 |
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| Jasper Therapeutics Com New (JSPR) | 0.0 | $60k | 25k | 2.38 |
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| Traws Pharma Com New (TRAW) | 0.0 | $53k | 29k | 1.85 |
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| Theriva Biologics Com New (TOVX) | 0.0 | $49k | 120k | 0.41 |
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| Synlogic Com New (SYBX) | 0.0 | $35k | 20k | 1.69 |
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| Neumora Therapeutics (NMRA) | 0.0 | $23k | 13k | 1.82 |
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| Autonomix Med Com New (AMIX) | 0.0 | $22k | 20k | 1.08 |
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Past Filings by Ikarian Capital
SEC 13F filings are viewable for Ikarian Capital going back to 2019
- Ikarian Capital 2025 Q3 filed Nov. 14, 2025
- Ikarian Capital 2025 Q2 filed Aug. 14, 2025
- Ikarian Capital 2025 Q1 filed May 15, 2025
- Ikarian Capital 2024 Q4 filed Feb. 14, 2025
- Ikarian Capital 2024 Q3 filed Nov. 14, 2024
- Ikarian Capital 2024 Q2 filed Aug. 14, 2024
- Ikarian Capital 2024 Q1 restated filed May 17, 2024
- Ikarian Capital 2024 Q1 filed May 15, 2024
- Ikarian Capital 2023 Q4 filed Feb. 14, 2024
- Ikarian Capital 2023 Q3 filed Nov. 14, 2023
- Ikarian Capital 2023 Q2 filed Aug. 14, 2023
- Ikarian Capital 2023 Q1 filed May 15, 2023
- Ikarian Capital 2022 Q4 filed Feb. 14, 2023
- Ikarian Capital 2022 Q3 filed Nov. 14, 2022
- Ikarian Capital 2022 Q2 filed Aug. 12, 2022
- Ikarian Capital 2022 Q1 filed May 13, 2022