5AM Venture Management
Latest statistics and disclosures from 5AM Venture Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are SKYE, TRDA, PHVS, CAMP, CNTA, and represent 42.76% of 5AM Venture Management's stock portfolio.
- Added to shares of these 2 stocks: CAMP (+$8.8M), MRSN.
- Started 1 new stock position in MRSN.
- Reduced shares in these 9 stocks: DNTH (-$24M), MLTX (-$13M), VOR (-$10M), VKTX (-$5.0M), SCPH, CNTA, SKYE, Mersana Therapeutics, TRDA.
- Sold out of its positions in Mersana Therapeutics, MLTX, SCPH, VKTX, VOR.
- 5AM Venture Management was a net seller of stock by $-54M.
- 5AM Venture Management has $273M in assets under management (AUM), dropping by 4.97%.
- Central Index Key (CIK): 0001799883
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Portfolio Holdings for 5AM Venture Management
5AM Venture Management holds 25 positions in its portfolio as reported in the September 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Skye Bioscience Com New (SKYE) | 13.9 | $38M | -2% | 9.7M | 3.93 |
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| Entrada Therapeutics (TRDA) | 9.0 | $25M | 4.3M | 5.80 |
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| Pharvaris N V (PHVS) | 7.3 | $20M | 798k | 24.95 |
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| Camp4 Therapeutics Corp (CAMP) | 6.4 | $18M | +100% | 5.9M | 3.00 |
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| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 6.0 | $17M | -18% | 681k | 24.25 |
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| Miragen Therapeutics (VRDN) | 5.8 | $16M | 737k | 21.58 |
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| Enliven Therapeutics (ELVN) | 5.8 | $16M | 773k | 20.47 |
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| Eyepoint Pharmaceuticals Com New (EYPT) | 5.5 | $15M | 1.1M | 14.24 |
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| Dianthus Therapeutics (DNTH) | 5.3 | $14M | -62% | 365k | 39.35 |
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| Tyra Biosciences (TYRA) | 4.8 | $13M | 939k | 13.99 |
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| Celldex Therapeutics Com New (CLDX) | 4.7 | $13M | 497k | 25.87 |
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| Erasca (ERAS) | 4.3 | $12M | 5.4M | 2.18 |
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| Praxis Precision Medicines I Com New (PRAX) | 3.3 | $9.0M | 170k | 53.00 |
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| Gh Research Ordinary Shares (GHRS) | 3.0 | $8.2M | 573k | 14.30 |
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| Tectonic Therapeutic (TECX) | 2.9 | $8.0M | 512k | 15.69 |
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| Biohaven (BHVN) | 2.6 | $7.2M | 479k | 15.01 |
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| Artiva Biotherapeutics (ARTV) | 2.5 | $6.8M | 2.4M | 2.87 |
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| Surrozen Com New (SRZN) | 1.5 | $4.0M | 310k | 12.88 |
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| Protara Therapeutics Com Stk (TARA) | 1.3 | $3.5M | 800k | 4.35 |
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| Alector (ALEC) | 1.1 | $2.9M | 996k | 2.96 |
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| Silence Therapeutics Ads (SLN) | 0.9 | $2.5M | 476k | 5.19 |
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| Adverum Biotechnologies Com New (ADVM) | 0.9 | $2.5M | 542k | 4.53 |
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| Rallybio Corp (RLYB) | 0.7 | $1.8M | 3.6M | 0.50 |
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| Zentalis Pharmaceuticals (ZNTL) | 0.3 | $740k | 490k | 1.51 |
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| Mersana Therapeutics (MRSN) | 0.1 | $405k | NEW | 52k | 7.76 |
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Past Filings by 5AM Venture Management
SEC 13F filings are viewable for 5AM Venture Management going back to 2019
- 5AM Venture Management 2025 Q3 filed Nov. 14, 2025
- 5AM Venture Management 2025 Q2 filed Aug. 14, 2025
- 5AM Venture Management 2025 Q1 filed May 15, 2025
- 5AM Venture Management 2024 Q4 filed Feb. 14, 2025
- 5AM Venture Management 2024 Q3 filed Nov. 14, 2024
- 5AM Venture Management 2024 Q2 filed Aug. 14, 2024
- 5AM Venture Management 2024 Q1 filed May 15, 2024
- 5AM Venture Management 2023 Q4 filed Feb. 14, 2024
- 5AM Venture Management 2023 Q3 filed Nov. 14, 2023
- 5AM Venture Management 2023 Q2 filed Aug. 14, 2023
- 5AM Venture Management 2023 Q1 filed May 15, 2023
- 5AM Venture Management 2022 Q4 filed Feb. 14, 2023
- 5AM Venture Management 2022 Q3 filed Nov. 14, 2022
- 5AM Venture Management 2022 Q2 filed Aug. 15, 2022
- 5AM Venture Management 2022 Q1 filed May 16, 2022
- 5AM Venture Management 2021 Q4 filed Feb. 3, 2022