5AM Venture Management
Latest statistics and disclosures from 5AM Venture Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are TRDA, CAMP, TYRA, VRDN, PHVS, and represent 47.09% of 5AM Venture Management's stock portfolio.
- Added to shares of these 7 stocks: MPLT (+$17M), ZNTL, TARA, BHVN, TYRA, TECX, SRZN.
- Started 1 new stock position in MPLT.
- Reduced shares in these 7 stocks: DNTH (-$14M), PRAX (-$9.0M), ALEC, CNTA, ADVM, TRDA, MRSN.
- Sold out of its positions in ADVM, ALEC, DNTH, MRSN, PRAX.
- 5AM Venture Management was a net seller of stock by $-312k.
- 5AM Venture Management has $318M in assets under management (AUM), dropping by 16.50%.
- Central Index Key (CIK): 0001799883
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Positions held by 5AM Venture Management consolidated in one spreadsheet with up to 7 years of data
Download as csvPortfolio Holdings for 5AM Venture Management
5AM Venture Management holds 21 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Entrada Therapeutics (TRDA) | 13.1 | $42M | -4% | 4.1M | 10.28 |
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| Camp4 Therapeutics Corp (CAMP) | 11.3 | $36M | 5.9M | 6.13 |
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| Tyra Biosciences (TYRA) | 8.5 | $27M | +9% | 1.0M | 26.29 |
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| Miragen Therapeutics (VRDN) | 7.2 | $23M | 737k | 31.12 |
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| Pharvaris N V (PHVS) | 7.0 | $22M | 798k | 27.75 |
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| Erasca (ERAS) | 6.3 | $20M | 5.4M | 3.72 |
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| Eyepoint Com New (EYPT) | 6.0 | $19M | 1.1M | 18.27 |
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| Maplight Therapeutics (MPLT) | 5.2 | $17M | NEW | 950k | 17.57 |
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| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 4.6 | $15M | -14% | 581k | 25.01 |
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| Celldex Therapeutics Com New (CLDX) | 4.2 | $14M | 497k | 27.16 |
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| Tectonic Therapeutic (TECX) | 4.0 | $13M | +18% | 607k | 20.86 |
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| Enliven Therapeutics (ELVN) | 3.7 | $12M | 773k | 15.40 |
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| Artiva Biotherapeutics (ARTV) | 3.2 | $10M | 2.4M | 4.29 |
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| Surrozen Com New (SRZN) | 2.8 | $8.8M | +25% | 388k | 22.60 |
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| Biohaven (BHVN) | 2.6 | $8.3M | +54% | 739k | 11.29 |
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| Protara Therapeutics Com Stk (TARA) | 2.3 | $7.3M | +71% | 1.4M | 5.33 |
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| Gh Research Ordinary Shares (GHRS) | 2.3 | $7.3M | 573k | 12.70 |
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| Skye Bioscience Com New (SKYE) | 2.3 | $7.3M | 9.7M | 0.75 |
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| Zentalis Pharmaceuticals (ZNTL) | 1.7 | $5.3M | +705% | 3.9M | 1.35 |
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| Silence Therapeutics Ads (SLN) | 0.9 | $2.9M | 476k | 6.08 |
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| Rallybio Corp (RLYB) | 0.8 | $2.5M | 3.6M | 0.69 |
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Past Filings by 5AM Venture Management
SEC 13F filings are viewable for 5AM Venture Management going back to 2019
- 5AM Venture Management 2025 Q4 filed Feb. 17, 2026
- 5AM Venture Management 2025 Q3 filed Nov. 14, 2025
- 5AM Venture Management 2025 Q2 filed Aug. 14, 2025
- 5AM Venture Management 2025 Q1 filed May 15, 2025
- 5AM Venture Management 2024 Q4 filed Feb. 14, 2025
- 5AM Venture Management 2024 Q3 filed Nov. 14, 2024
- 5AM Venture Management 2024 Q2 filed Aug. 14, 2024
- 5AM Venture Management 2024 Q1 filed May 15, 2024
- 5AM Venture Management 2023 Q4 filed Feb. 14, 2024
- 5AM Venture Management 2023 Q3 filed Nov. 14, 2023
- 5AM Venture Management 2023 Q2 filed Aug. 14, 2023
- 5AM Venture Management 2023 Q1 filed May 15, 2023
- 5AM Venture Management 2022 Q4 filed Feb. 14, 2023
- 5AM Venture Management 2022 Q3 filed Nov. 14, 2022
- 5AM Venture Management 2022 Q2 filed Aug. 15, 2022
- 5AM Venture Management 2022 Q1 filed May 16, 2022