5AM Venture Management

Latest statistics and disclosures from 5AM Venture Management's latest quarterly 13F-HR filing:

  • Top 5 stock holdings are ERAS, TRDA, TYRA, CAMP, CNTA, and represent 54.41% of 5AM Venture Management's stock portfolio.
  • Added to shares of these 2 stocks: ALXO (+$6.1M), RLYB.
  • Started 2 new stock positions in ALXO, RLYB.
  • Reduced shares in these 4 stocks: ERAS (-$31M), VRDN (-$23M), ELVN (-$12M), Rallybio Corp.
  • Sold out of its positions in ELVN, Rallybio Corp, VRDN.
  • 5AM Venture Management was a net seller of stock by $-60M.
  • 5AM Venture Management has $360M in assets under management (AUM), dropping by 13.24%.
  • Central Index Key (CIK): 0001799883

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Portfolio Holdings for 5AM Venture Management

5AM Venture Management holds 20 positions in its portfolio as reported in the March 2026 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Erasca (ERAS) 15.7 $56M -35% 3.5M 16.18
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Entrada Therapeutics (TRDA) 14.2 $51M 4.1M 12.62
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Tyra Biosciences (TYRA) 10.9 $39M 1.0M 38.30
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Camp4 Therapeutics Corp (CAMP) 7.2 $26M 5.9M 4.41
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Centessa Pharmaceuticals Sponsored Ads (CNTA) 6.4 $23M 581k 39.72
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Pharvaris N V (PHVS) 6.3 $23M 798k 28.25
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Maplight Therapeutics (MPLT) 5.4 $19M 950k 20.33
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Tectonic Therapeutic (TECX) 5.2 $19M 607k 30.91
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Celldex Therapeutics Com New (CLDX) 4.4 $16M 497k 31.72
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Artiva Biotherapeutics (ARTV) 4.2 $15M 2.4M 6.44
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Eyepoint Com New (EYPT) 3.8 $14M 1.1M 12.89
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Surrozen Com New (SRZN) 3.1 $11M 388k 29.13
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Zentalis Pharmaceuticals (ZNTL) 2.6 $9.2M 3.9M 2.34
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Gh Research Ordinary Shares (GHRS) 2.2 $8.1M 573k 14.06
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Protara Therapeutics Com Stk (TARA) 2.0 $7.1M 1.4M 5.21
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Biohaven (BHVN) 1.7 $6.3M 739k 8.46
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Alx Oncology Hldgs (ALXO) 1.7 $6.1M NEW 3.1M 2.00
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Skye Bioscience Com New (SKYE) 1.7 $6.0M 9.7M 0.61
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Rallybio Corp (RLYB) 0.7 $2.6M NEW 292k 8.97
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Silence Therapeutics Ads (SLN) 0.7 $2.5M 476k 5.27
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Past Filings by 5AM Venture Management

SEC 13F filings are viewable for 5AM Venture Management going back to 2019

View all past filings