Rtw Investments
Latest statistics and disclosures from Rtw Investments's latest quarterly 13F-HR filing:
- Top 5 stock holdings are MDGL, ARGX, RNA, PTCT, INSM, and represent 34.82% of Rtw Investments's stock portfolio.
- Added to shares of these 10 stocks: RNA (+$76M), COGT (+$50M), RARE (+$47M), XNCR (+$45M), GH (+$39M), AQST (+$35M), ABVX (+$30M), BLTE (+$23M), ALEC (+$21M), CNTA (+$19M).
- Started 10 new stock positions in BLTE, PEPG, AQST, Imagenebio, CMPX, ALEC, ABVX, COGT, LRMR, Heartflow Inc/Sh.
- Reduced shares in these 10 stocks: VRNA (-$289M), MRUS (-$186M), ZLAB (-$110M), NTRA (-$96M), ALKS (-$90M), ABT (-$60M), AXSM (-$48M), DGX (-$48M), QURE (-$43M), ACAD (-$40M).
- Sold out of its positions in ABT, CRGX, CBLL, ETNB, IMUX, MLTX, SLNO, VRNA, KMTS.
- Rtw Investments was a net seller of stock by $-661M.
- Rtw Investments has $8.1B in assets under management (AUM), dropping by 15.59%.
- Central Index Key (CIK): 0001493215
Tip: Access up to 7 years of quarterly data
Positions held by Rtw Investments consolidated in one spreadsheet with up to 7 years of data
Download as csv
Download as Excel
Portfolio Holdings for Rtw Investments
Rtw Investments holds 74 positions in its portfolio as reported in the September 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Madrigal Pharmaceuticals (MDGL) | 11.3 | $914M | 2.0M | 458.66 |
|
|
| Argenx Se Sponsored Adr (ARGX) | 6.1 | $497M | 674k | 737.56 |
|
|
| Avidity Biosciences Ord (RNA) | 6.1 | $496M | +18% | 11M | 43.57 |
|
| Ptc Therapeutics I (PTCT) | 5.9 | $475M | 7.7M | 61.37 |
|
|
| Insmed Com Par $.01 (INSM) | 5.5 | $444M | 3.1M | 144.01 |
|
|
| Protagonist Therapeutics (PTGX) | 4.7 | $382M | 5.8M | 66.43 |
|
|
| Natera (NTRA) | 4.0 | $322M | -22% | 2.0M | 160.97 |
|
| Akero Therapeutics (AKRO) | 3.2 | $260M | 5.5M | 47.48 |
|
|
| Uniqure Nv SHS (QURE) | 3.2 | $258M | -14% | 4.4M | 58.37 |
|
| Penumbra (PEN) | 2.7 | $220M | 867k | 253.32 |
|
|
| RadNet (RDNT) | 2.6 | $215M | +4% | 2.8M | 76.21 |
|
| Merus N V (MRUS) | 2.3 | $191M | -49% | 2.0M | 94.15 |
|
| Tarsus Pharmaceuticals (TARS) | 2.3 | $189M | +2% | 3.2M | 59.43 |
|
| Stryker Corporation (SYK) | 2.2 | $181M | -17% | 490k | 369.67 |
|
| Immunocore Hldgs Ads (IMCR) | 2.2 | $177M | 4.9M | 36.33 |
|
|
| ACADIA Pharmaceuticals (ACAD) | 1.9 | $153M | -20% | 7.1M | 21.34 |
|
| Cytokinetics Com New (CYTK) | 1.8 | $150M | 2.7M | 54.96 |
|
|
| Neurocrine Biosciences (NBIX) | 1.8 | $149M | 1.1M | 140.38 |
|
|
| Axsome Therapeutics (AXSM) | 1.7 | $136M | -26% | 1.1M | 121.45 |
|
| Stoke Therapeutics (STOK) | 1.5 | $120M | 5.1M | 23.50 |
|
|
| Apogee Therapeutics (APGE) | 1.3 | $108M | 2.7M | 39.73 |
|
|
| Establishment Labs Holdings Ord (ESTA) | 1.3 | $106M | 2.6M | 40.99 |
|
|
| Masimo Corporation (MASI) | 1.2 | $101M | 683k | 147.55 |
|
|
| Ultragenyx Pharmaceutical (RARE) | 1.2 | $98M | +90% | 3.3M | 30.08 |
|
| Guardant Health (GH) | 1.1 | $93M | +72% | 1.5M | 62.48 |
|
| Urogen Pharma (URGN) | 1.1 | $91M | 4.5M | 19.95 |
|
|
| Intuitive Surgical Com New (ISRG) | 1.1 | $91M | 203k | 447.23 |
|
|
| Gh Research Ordinary Shares (GHRS) | 1.0 | $80M | 5.6M | 14.30 |
|
|
| Taysha Gene Therapies Com Shs (TSHA) | 1.0 | $80M | -2% | 24M | 3.27 |
|
| Zai Lab Adr (ZLAB) | 1.0 | $78M | -58% | 2.3M | 33.89 |
|
| Immatics SHS (IMTX) | 0.9 | $75M | +26% | 8.8M | 8.52 |
|
| Xencor (XNCR) | 0.9 | $73M | +158% | 6.2M | 11.73 |
|
| Cg Oncology (CGON) | 0.8 | $69M | 1.7M | 40.28 |
|
|
| Beta Bionics (BBNX) | 0.8 | $66M | 3.3M | 19.87 |
|
|
| Spyre Therapeutics Com New (SYRE) | 0.7 | $61M | 3.6M | 16.76 |
|
|
| Rocket Pharmaceuticals (RCKT) | 0.7 | $58M | 18M | 3.26 |
|
|
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.7 | $56M | +49% | 2.3M | 24.25 |
|
| Alkermes SHS (ALKS) | 0.6 | $50M | -64% | 1.7M | 30.00 |
|
| Compass Pathways Sponsored Ads (CMPS) | 0.6 | $50M | +5% | 8.7M | 5.73 |
|
| Cogent Biosciences (COGT) | 0.6 | $50M | NEW | 3.5M | 14.36 |
|
| Verastem Com New (VSTM) | 0.6 | $48M | +27% | 5.4M | 8.83 |
|
| Quest Diagnostics Incorporated (DGX) | 0.6 | $48M | -50% | 250k | 190.58 |
|
| Lenz Therapeutics (LENZ) | 0.5 | $40M | 863k | 46.58 |
|
|
| Rapt Therapeutics Com New (RAPT) | 0.5 | $38M | 1.5M | 25.79 |
|
|
| Oruka Therapeutics (ORKA) | 0.5 | $37M | 1.9M | 19.23 |
|
|
| Dyne Therapeutics (DYN) | 0.5 | $37M | +70% | 2.9M | 12.65 |
|
| Crinetics Pharmaceuticals In (CRNX) | 0.4 | $36M | +86% | 872k | 41.65 |
|
| Aquestive Therapeutics (AQST) | 0.4 | $35M | NEW | 6.3M | 5.59 |
|
| Abivax Sa Sponsored Ads (ABVX) | 0.4 | $30M | NEW | 350k | 84.90 |
|
| Ge Healthcare Technologies I Common Stock (GEHC) | 0.4 | $30M | -37% | 394k | 75.10 |
|
| Replimune Group (REPL) | 0.3 | $27M | +209% | 6.4M | 4.19 |
|
| Neurogene (NGNE) | 0.3 | $24M | 1.4M | 17.33 |
|
|
| Belite Bio Sponsored Ads (BLTE) | 0.3 | $23M | NEW | 313k | 74.00 |
|
| Alector (ALEC) | 0.3 | $21M | NEW | 7.0M | 2.96 |
|
| Health Sciences Acq Corp 2 (OBIO) | 0.3 | $21M | 8.3M | 2.48 |
|
|
| Corvus Pharmaceuticals (CRVS) | 0.2 | $20M | 2.7M | 7.37 |
|
|
| Exagen (XGN) | 0.2 | $19M | 1.7M | 10.99 |
|
|
| Heartflow Inc/Sh | 0.2 | $17M | NEW | 495k | 33.66 |
|
| Tempus Ai Cl A (TEM) | 0.2 | $16M | -50% | 200k | 80.71 |
|
| Jade Biosciences Com New (JBIO) | 0.2 | $13M | 1.4M | 8.63 |
|
|
| Cytomx Therapeutics (CTMX) | 0.1 | $11M | 3.5M | 3.19 |
|
|
| Cullinan Oncology (CGEM) | 0.1 | $10M | 1.7M | 5.93 |
|
|
| Larimar Therapeutics (LRMR) | 0.1 | $10M | NEW | 3.1M | 3.23 |
|
| Compass Therapeutics (CMPX) | 0.1 | $8.8M | NEW | 2.5M | 3.50 |
|
| Perceptive Cap Solutions Cor Cl A Ord Shs (PCSC) | 0.1 | $7.8M | 743k | 10.56 |
|
|
| Pepgen (PEPG) | 0.1 | $6.9M | NEW | 1.5M | 4.62 |
|
| Wave Life Sciences SHS (WVE) | 0.1 | $6.6M | 900k | 7.32 |
|
|
| Allurion Technologies Common Stock (ALUR) | 0.1 | $5.2M | 2.5M | 2.05 |
|
|
| Milestone Pharmaceuticals (MIST) | 0.1 | $5.0M | 2.5M | 2.00 |
|
|
| Omada Health (OMDA) | 0.1 | $4.4M | 200k | 22.11 |
|
|
| Tenax Therapeutics Com New (TENX) | 0.0 | $2.9M | 378k | 7.61 |
|
|
| Imagenebio | 0.0 | $2.7M | NEW | 334k | 8.15 |
|
| Adagio Med Hldgs (ADGM) | 0.0 | $406k | 209k | 1.94 |
|
|
| Rocket Pharmaceuticals *w Exp 09/02/202 (RCKTW) | 0.0 | $14k | 350k | 0.04 |
|
Past Filings by Rtw Investments
SEC 13F filings are viewable for Rtw Investments going back to 2014
- Rtw Investments 2025 Q3 filed Nov. 14, 2025
- Rtw Investments 2025 Q2 filed Aug. 14, 2025
- Rtw Investments 2025 Q1 filed May 15, 2025
- Rtw Investments 2024 Q4 filed Feb. 14, 2025
- Rtw Investments 2024 Q3 filed Nov. 14, 2024
- Rtw Investments 2024 Q2 filed Aug. 14, 2024
- Rtw Investments 2024 Q1 filed May 15, 2024
- Rtw Investments 2023 Q4 filed Feb. 14, 2024
- Rtw Investments 2023 Q3 filed Nov. 14, 2023
- Rtw Investments 2023 Q2 filed Aug. 14, 2023
- Rtw Investments 2023 Q1 filed May 15, 2023
- Rtw Investments 2022 Q4 filed Feb. 14, 2023
- Rtw Investments 2022 Q3 filed Nov. 14, 2022
- Rtw Investments 2022 Q2 filed Aug. 15, 2022
- Rtw Investments 2022 Q1 filed May 16, 2022
- Rtw Investments 2021 Q4 filed Feb. 14, 2022