DAFNA Capital Management as of Dec. 31, 2025
Portfolio Holdings for DAFNA Capital Management
DAFNA Capital Management holds 77 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Revolution Medicines (RVMD) | 11.2 | $48M | 605k | 79.65 | |
| Spdr S&p Biotech Etf Etf (XBI) | 9.5 | $41M | 337k | 121.93 | |
| Stereotaxis Com New (STXS) | 7.3 | $32M | 14M | 2.30 | |
| AtriCure (ATRC) | 5.5 | $24M | 597k | 39.56 | |
| Cytokinetics Com New (CYTK) | 5.5 | $24M | 371k | 63.54 | |
| Ideaya Biosciences (IDYA) | 4.1 | $18M | 507k | 34.57 | |
| Axogen (AXGN) | 3.6 | $16M | 477k | 32.73 | |
| Xenon Pharmaceuticals (XENE) | 3.0 | $13M | 288k | 44.82 | |
| Ishares Nasdaq Biotech Indx Etf (IBB) | 2.7 | $12M | 68k | 168.77 | |
| Biohaven (BHVN) | 2.5 | $11M | 955k | 11.29 | |
| Arcus Biosciences Incorporated (RCUS) | 2.4 | $10M | 431k | 23.83 | |
| Neurocrine Biosciences (NBIX) | 2.3 | $10M | 71k | 141.83 | |
| Day One Biopharmaceuticals I (DAWN) | 2.2 | $9.3M | 999k | 9.32 | |
| Tandem Diabetes Care Com New (TNDM) | 1.8 | $7.8M | 355k | 21.98 | |
| Ascendis Pharma A/s Sponsored Adr (ASND) | 1.4 | $6.0M | 28k | 213.24 | |
| Dex (DXCM) | 1.4 | $5.9M | 88k | 66.37 | |
| Syndax Pharmaceuticals (SNDX) | 1.4 | $5.8M | 278k | 21.01 | |
| Kalvista Pharmaceuticals (KALV) | 1.3 | $5.8M | 357k | 16.15 | |
| Compass Pathways Sponsored Ads (CMPS) | 1.3 | $5.6M | 811k | 6.90 | |
| Inogen (INGN) | 1.3 | $5.6M | 827k | 6.72 | |
| Ascendis Pharma A/s Note 2.250% 4/0 (Principal) | 1.3 | $5.5M | 4.0M | 1.36 | |
| Denali Therapeutics (DNLI) | 1.2 | $5.3M | 319k | 16.51 | |
| Mbx Biosciences (MBX) | 1.2 | $5.2M | 165k | 31.54 | |
| Bicara Therapeutics (BCAX) | 1.0 | $4.4M | 262k | 16.83 | |
| Galapagos Nv Spon Adr (GLPG) | 1.0 | $4.3M | 130k | 32.70 | |
| Astria Therapeutics | 0.9 | $4.0M | 305k | 13.09 | |
| Edgewise Therapeutics (EWTX) | 0.9 | $4.0M | 160k | 24.82 | |
| Immunovant (IMVT) | 0.9 | $3.8M | 151k | 25.42 | |
| Procept Biorobotics Corp (PRCT) | 0.9 | $3.8M | 120k | 31.46 | |
| Cybin Com New (HELP) | 0.9 | $3.7M | 455k | 8.18 | |
| Alkermes SHS (ALKS) | 0.8 | $3.6M | 130k | 27.98 | |
| Larimar Therapeutics (LRMR) | 0.8 | $3.6M | 939k | 3.81 | |
| Stoke Therapeutics (STOK) | 0.8 | $3.5M | 109k | 31.74 | |
| Lexeo Therapeutics (LXEO) | 0.8 | $3.4M | 341k | 9.93 | |
| BioCryst Pharmaceuticals (BCRX) | 0.8 | $3.3M | 418k | 7.80 | |
| Nektar Therapeutics Com New (NKTR) | 0.7 | $3.2M | 75k | 42.28 | |
| Proqr Therapeutics N V Shs Euro (PRQR) | 0.7 | $3.2M | 1.6M | 2.02 | |
| Century Therapeutics (IPSC) | 0.6 | $2.8M | 2.8M | 0.99 | |
| Immatics Nv SHS (IMTX) | 0.6 | $2.7M | 261k | 10.50 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.6 | $2.6M | 37k | 69.55 | |
| Maplight Therapeutics (MPLT) | 0.6 | $2.5M | 144k | 17.57 | |
| Align Technology (ALGN) | 0.6 | $2.5M | 16k | 156.15 | |
| Kura Oncology (KURA) | 0.6 | $2.5M | 236k | 10.39 | |
| Aquestive Therapeutics (AQST) | 0.6 | $2.4M | 376k | 6.46 | |
| Rapport Therapeutics (RAPP) | 0.5 | $2.3M | 75k | 30.34 | |
| Profound Medical Corp Com New (PROF) | 0.5 | $2.2M | 286k | 7.87 | |
| Silverback Therapeutics (SPRY) | 0.5 | $2.2M | 190k | 11.65 | |
| Mediwound Shs New (MDWD) | 0.5 | $2.1M | 114k | 18.46 | |
| Viking Therapeutics (VKTX) | 0.5 | $2.1M | 60k | 35.18 | |
| Insulet Corporation (PODD) | 0.5 | $2.0M | 6.9k | 284.24 | |
| Allogene Therapeutics (ALLO) | 0.4 | $1.9M | 1.4M | 1.37 | |
| Celldex Therapeutics Com New (CLDX) | 0.4 | $1.9M | 69k | 27.16 | |
| Tela Bio (TELA) | 0.4 | $1.7M | 1.4M | 1.18 | |
| Engene Holdings (ENGN) | 0.3 | $1.5M | 164k | 9.03 | |
| Verrica Pharmaceuticals Com Shs (VRCA) | 0.3 | $1.4M | 174k | 8.31 | |
| Alector (ALEC) | 0.3 | $1.4M | 908k | 1.56 | |
| Mineralys Therapeutics (MLYS) | 0.3 | $1.4M | 39k | 36.29 | |
| Annexon (ANNX) | 0.3 | $1.4M | 273k | 5.02 | |
| Oric Pharmaceuticals (ORIC) | 0.3 | $1.2M | 141k | 8.18 | |
| Accuray Incorporated (ARAY) | 0.3 | $1.2M | 1.4M | 0.82 | |
| Erasca (ERAS) | 0.2 | $947k | 254k | 3.72 | |
| Polypid (PYPD) | 0.2 | $902k | 208k | 4.34 | |
| Inspire Med Sys (INSP) | 0.2 | $793k | 8.6k | 92.23 | |
| Adicet Bio Com New (ACET) | 0.2 | $790k | 94k | 8.42 | |
| Foghorn Therapeutics (FHTX) | 0.2 | $685k | 127k | 5.40 | |
| Biontech Se Sponsored Ads (BNTX) | 0.2 | $666k | 7.0k | 95.20 | |
| Neurogene (NGNE) | 0.1 | $576k | 28k | 20.60 | |
| Fate Therapeutics (FATE) | 0.1 | $540k | 550k | 0.98 | |
| Health Sciences Acq Corp 2 (OBIO) | 0.1 | $526k | 127k | 4.15 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.1 | $457k | 65k | 7.08 | |
| Compugen Ord (CGEN) | 0.1 | $417k | 272k | 1.53 | |
| Karyopharm Therapeutics Com New (KPTI) | 0.1 | $375k | 51k | 7.36 | |
| Ultragenyx Pharmaceutical (RARE) | 0.1 | $368k | 16k | 23.00 | |
| Autolus Therapeutics Spon Ads (AUTL) | 0.1 | $357k | 179k | 1.99 | |
| Adc Therapeutics Sa SHS (ADCT) | 0.1 | $272k | 77k | 3.53 | |
| Brainsway Sponsored Ads (BWAY) | 0.1 | $247k | 13k | 19.02 | |
| Perspective Therapeutics Com New (CATX) | 0.0 | $138k | 50k | 2.75 |