Opaleye Management

Opaleye Management as of Sept. 30, 2015

Portfolio Holdings for Opaleye Management

Opaleye Management holds 49 positions in its portfolio as reported in the September 2015 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Chimerix (CMRX) 5.8 $12M 310k 38.20
Ultragenyx Pharmaceutical (RARE) 5.2 $11M 110k 96.31
Cempra 4.9 $10M 360k 27.84
Axogen (AXGN) 4.3 $8.7M 2.1M 4.12
Medgenics 4.1 $8.3M 1.1M 7.82
AMAG Pharmaceuticals 3.9 $7.9M 200k 39.73
Imprimis Pharmaceuticals 3.8 $7.7M 1.2M 6.42
Ariad Pharmaceuticals 3.8 $7.7M 1.3M 5.84
Retrophin 3.7 $7.5M 370k 20.26
Fibrogen (FGEN) 3.5 $7.1M 325k 21.92
Supernus Pharmaceuticals (SUPN) 3.2 $6.5M 460k 14.03
Zs Pharma 3.1 $6.2M 95k 65.66
Inotek Pharmaceuticals Corp conv 3.0 $6.0M 643k 9.40
Cara Therapeutics (CARA) 2.9 $5.9M 415k 14.29
Codexis (CDXS) 2.7 $5.5M 1.6M 3.39
Eagle Pharmaceuticals (EGRX) 2.7 $5.4M 73k 74.03
Flamel Technologies 2.5 $5.1M 310k 16.31
Geron Corporation (GERN) 2.5 $5.0M 1.8M 2.76
Neurocrine Biosciences (NBIX) 2.5 $5.0M 125k 39.78
Protalix Biotherapeutics Inc note 4.500% 9/1 2.1 $4.3M 3.6M 1.18
Ophthotech 2.1 $4.3M 105k 40.52
Affimed Therapeutics B V 1.8 $3.6M 590k 6.17
Cytrx 1.8 $3.6M 1.5M 2.37
Intec Pharma 1.7 $3.5M 630k 5.60
Amarin Corporation (AMRN) 1.7 $3.4M 1.8M 1.93
Zogenix 1.7 $3.4M 250k 13.50
Trillium Therapeutics, Inc. Cmn 1.6 $3.2M 245k 13.03
Tonix Pharmaceuticls 1.5 $3.0M 570k 5.29
Blueprint Medicines (BPMC) 1.4 $2.8M 130k 21.34
Adamas Pharmaceuticals 1.4 $2.8M 166k 16.74
Momenta Pharmaceuticals 1.3 $2.6M 160k 16.41
Tg Therapeutics (TGTX) 1.3 $2.6M 260k 10.08
Agile Therapeutics 1.3 $2.6M 385k 6.74
Avinger 1.3 $2.6M 175k 14.71
Nivalis Therapeutics 1.1 $2.3M 175k 12.97
XOMA CORP Common equity shares 1.1 $2.2M 3.0M 0.75
Foamix Pharmaceuticals 1.0 $2.1M 285k 7.33
Tenax Therapeutics 0.9 $1.9M 635k 3.00
Accelr8 Technology 0.8 $1.5M 95k 16.18
Auris Med Hldg 0.6 $1.3M 355k 3.56
Xenon Pharmaceuticals (XENE) 0.6 $1.2M 151k 8.26
Sage Therapeutics (SAGE) 0.4 $846k 20k 42.30
Evoke Pharma 0.4 $757k 260k 2.91
Innocoll 0.3 $695k 56k 12.51
Celgene Corp right 12/31/2011 0.3 $547k 340k 1.61
Alder Biopharmaceuticals 0.3 $527k 16k 32.73
Cynapsus Therapeutics 0.2 $469k 29k 16.17
Biolinerx Ltd-spons 0.2 $383k 250k 1.53
Tracon Pharmaceuticals 0.1 $119k 12k 9.78