Opaleye Management

Opaleye Management as of March 31, 2016

Portfolio Holdings for Opaleye Management

Opaleye Management holds 50 positions in its portfolio as reported in the March 2016 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Axogen (AXGN) 7.2 $11M 2.1M 5.36
Ariad Pharmaceuticals 5.0 $8.0M 1.3M 6.39
Ultragenyx Pharmaceutical (RARE) 4.4 $7.0M 110k 63.31
Fibrogen (FGEN) 4.4 $6.9M 325k 21.29
Protalix Biotherapeutics Inc note 4.500% 9/1 4.3 $6.9M 8.2M 0.84
Medgenics 4.3 $6.9M 1.6M 4.40
Adamas Pharmaceuticals 3.8 $6.1M 320k 18.95
Cara Therapeutics (CARA) 3.4 $5.3M 855k 6.22
Sage Therapeutics (SAGE) 3.3 $5.3M 165k 32.06
AMAG Pharmaceuticals 3.2 $5.1M 220k 23.40
Imprimis Pharmaceuticals 3.1 $5.0M 1.3M 3.97
Inotek Pharmaceuticals Corp conv 3.0 $4.8M 645k 7.40
DepoMed 2.9 $4.5M 325k 13.93
Agios Pharmaceuticals (AGIO) 2.7 $4.3M 105k 40.60
Cytrx 2.6 $4.1M 1.4M 2.86
Blueprint Medicines (BPMC) 2.5 $4.0M 220k 18.05
Geron Corporation (GERN) 2.4 $3.9M 1.3M 2.92
Foamix Pharmaceuticals 2.4 $3.8M 590k 6.52
Codexis (CDXS) 2.3 $3.7M 1.2M 3.11
Tg Therapeutics (TGTX) 2.2 $3.5M 415k 8.52
Chimerix (CMRX) 2.2 $3.4M 675k 5.11
Ophthotech 2.1 $3.4M 80k 42.28
Immunomedics 2.1 $3.3M 1.3M 2.50
Xenon Pharmaceuticals (XENE) 1.8 $2.8M 400k 6.99
Amarin Corporation (AMRN) 1.7 $2.7M 1.8M 1.53
Intec Pharma 1.7 $2.6M 638k 4.12
Nabriva Therapeutics 1.6 $2.5M 274k 8.96
Eagle Pharmaceuticals (EGRX) 1.5 $2.4M 60k 40.50
Affimed Therapeutics B V 1.4 $2.3M 610k 3.74
Zogenix 1.4 $2.2M 240k 9.24
Retrophin 1.3 $2.0M 150k 13.66
Supernus Pharmaceuticals (SUPN) 1.2 $1.9M 125k 15.25
Trillium Therapeutics, Inc. Cmn 1.1 $1.8M 195k 9.25
Edge Therapeutics 1.1 $1.7M 185k 9.15
Cynapsus Therapeutics 0.9 $1.4M 121k 11.90
Adaptimmune Therapeutics (ADAP) 0.9 $1.4M 175k 8.13
Corium Intl 0.9 $1.4M 360k 3.86
Auris Med Hldg 0.8 $1.2M 340k 3.64
Ohr Pharmaceutical 0.7 $1.2M 366k 3.21
XOMA CORP Common equity shares 0.7 $1.0M 1.4M 0.77
Tenax Therapeutics 0.7 $1.0M 500k 2.05
Achaogen 0.4 $704k 255k 2.76
Nektar Therapeutics (NKTR) 0.4 $688k 50k 13.76
Medivation 0.4 $667k 15k 46.00
Evoke Pharma 0.4 $662k 130k 5.09
Neuroderm Ltd F 0.3 $544k 39k 14.13
Nivalis Therapeutics 0.3 $417k 100k 4.17
Aclaris Therapeutics (ACRS) 0.2 $341k 18k 18.94
Biolinerx Ltd-spons 0.2 $255k 250k 1.02
Chiasma 0.1 $183k 20k 9.15