Palo Alto Investors

Palo Alto Investors as of Dec. 31, 2015

Portfolio Holdings for Palo Alto Investors

Companies in the Palo Alto Investors portfolio as of the December 2015 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Abiomed (ABMD) 14.5 $261M 2.9M 90.28
Anacor Pharmaceuticals In 13.8 $247M 2.2M 112.97
United Therapeutics Corporation (UTHR) 13.2 $238M 1.5M 156.61
BioMarin Pharmaceutical (BMRN) 7.8 $140M 1.3M 104.76
Clovis Oncology (CLVS) 6.9 $124M 3.5M 35.00
Insmed (INSM) 4.8 $87M 4.8M 18.15
AMAG Pharmaceuticals (AMAG) 4.8 $86M 2.8M 30.19
Wright Medical Group Nv (WMGI) 2.9 $52M 2.1M 24.18
Endo International (ENDP) 2.7 $49M 801k 61.22
Prothena (PRTA) 2.6 $47M 696k 68.11
Epizyme (EPZM) 2.4 $43M 2.7M 16.02
Karyopharm Therapeutics (KPTI) 2.3 $41M 3.1M 13.25
Vanda Pharmaceuticals (VNDA) 2.1 $38M 4.0M 9.31
Cempra 2.0 $37M 1.2M 31.13
Amicus Therapeutics (FOLD) 1.9 $34M 3.6M 9.70
Celgene Corporation 1.8 $32M 271k 119.76
Gilead Sciences (GILD) 1.7 $31M 303k 101.19
Medivation 1.4 $25M 510k 48.34
Momenta Pharmaceuticals (MNTA) 1.2 $22M 1.5M 14.84
Shire 1.2 $22M 105k 205.00
STAAR Surgical Company (STAA) 1.1 $19M 2.7M 7.14
Sequenom 0.9 $16M 10.0M 1.64
Zeltiq Aesthetics 0.9 $16M 574k 28.53
Rigel Pharmaceuticals (RIGL) 0.9 $16M 5.2M 3.03
Ariad Pharmaceuticals 0.8 $14M 2.3M 6.25
HeartWare International 0.7 $12M 246k 50.40
Alimera Sciences 0.4 $7.3M 3.0M 2.42
Sunesis Pharmaceuticals 0.3 $6.3M 7.0M 0.90
Aimmune Therapeutics (AIMT) 0.3 $6.0M 326k 18.45
Acelrx Pharmaceuticals (ACRX) 0.3 $5.5M 1.4M 3.85
Idera Pharmaceuticals 0.2 $3.9M 1.3M 3.09
EXACT Sciences Corporation (EXAS) 0.2 $3.7M 396k 9.23
Dicerna Pharmaceuticals (DRNA) 0.2 $3.2M 268k 11.87
Orexigen Therapeutics 0.2 $2.9M 1.7M 1.72
Align Technology (ALGN) 0.1 $1.8M 28k 65.86
Alcobra 0.1 $1.6M 254k 6.28
Histogenics Corp Cmn 0.1 $1.6M 455k 3.50
Intrexon 0.1 $1.4M 47k 30.15
Cytokinetics (CYTK) 0.1 $1.3M 124k 10.46
Sophiris Bio (SPHS) 0.1 $879k 494k 1.78
Marinus Pharmaceuticals (MRNS) 0.0 $451k 59k 7.64
Uniqure Nv (QURE) 0.0 $338k 21k 16.53
Zogenix (ZGNX) 0.0 $422k 29k 14.76