Palo Alto Investors

Palo Alto Investors as of Dec. 31, 2010

Portfolio Holdings for Palo Alto Investors

Palo Alto Investors holds 50 positions in its portfolio as reported in the December 2010 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Cyberonics 10.6 $104M 3.3M 31.02
ViroPharma Incorporated 8.7 $85M 4.9M 17.32
Onyx Pharmaceuticals 6.8 $67M 1.8M 36.87
AMAG Pharmaceuticals 5.8 $57M 3.1M 18.10
Savient Pharmaceuticals 5.4 $53M 4.8M 11.14
Momenta Pharmaceuticals 5.1 $49M 3.3M 14.97
Auxilium Pharmaceuticals 4.5 $44M 2.1M 21.10
Questcor Pharmaceuticals 4.3 $42M 2.8M 14.73
United Therapeutics Corporation (UTHR) 3.8 $37M 589k 63.22
Medicis Pharmaceutical Corporation 3.2 $32M 1.2M 26.79
ArthroCare Corporation 3.2 $31M 1.0M 31.06
BioMarin Pharmaceutical (BMRN) 3.2 $31M 1.2M 26.93
Amicus Therapeutics (FOLD) 3.1 $30M 6.4M 4.70
Northern Oil & Gas 2.8 $27M 1.0M 27.21
Ceragon Networks (CRNT) 2.7 $27M 2.0M 13.18
InterMune 2.3 $23M 622k 36.40
Cubist Pharmaceuticals 2.2 $22M 1.0M 21.40
Sequenom 1.8 $18M 2.2M 8.03
Contango Oil & Gas Company 1.6 $15M 260k 57.93
STAAR Surgical Company (STAA) 1.5 $15M 2.5M 6.10
Evergreen Solar Inc note 4.000% 7/1 1.3 $13M 32M 0.40
Vanda Pharmaceuticals (VNDA) 1.1 $11M 1.1M 9.46
Alimera Sciences 1.1 $10M 1.0M 10.38
Genzyme Corporation 1.0 $10M 143k 71.20
Medivation 1.0 $9.4M 622k 15.17
BroadVision 0.9 $9.2M 739k 12.50
Abiomed 0.9 $9.0M 940k 9.61
Triangle Petroleum Corporation csus 0.9 $8.9M 1.4M 6.50
Toreador Resources Corporation 0.9 $8.3M 538k 15.52
interCLICK 0.8 $8.3M 1.5M 5.37
Sonde Resources 0.8 $8.1M 2.2M 3.65
EnerNOC 0.8 $7.7M 320k 23.91
Genoptix 0.6 $5.9M 312k 19.02
Celgene Corporation 0.6 $5.7M 97k 59.14
Orexigen Therapeutics 0.6 $5.5M 680k 8.08
NxStage Medical 0.4 $4.1M 166k 24.88
Gilead Sciences (GILD) 0.4 $3.9M 109k 36.24
pSivida 0.4 $3.9M 770k 5.11
NuVasive 0.4 $3.8M 148k 25.65
Riverbed Technology 0.4 $3.5M 100k 35.17
Energy Recovery (ERII) 0.3 $2.9M 791k 3.66
Aegerion Pharmaceuticals 0.3 $2.5M 178k 14.17
Procera Networks 0.2 $2.2M 3.5M 0.62
First Solar (FSLR) 0.2 $2.0M 15k 130.13
Orthovita 0.2 $1.7M 834k 2.01
Protalix BioTherapeutics 0.1 $1.4M 136k 9.98
Cytokinetics 0.1 $1.3M 632k 2.09
Guaranty Ban 0.1 $1.1M 799k 1.42
Rigel Pharmaceuticals 0.1 $560k 74k 7.53
Spectrum Pharmaceuticals 0.0 $343k 50k 6.86