Hambrecht & Quist Capital Management

Tekla Capital Management as of Dec. 31, 2014

Portfolio Holdings for Tekla Capital Management

Tekla Capital Management holds 92 positions in its portfolio as reported in the December 2014 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Celgene Corporation 10.4 $223M 2.0M 111.86
Gilead Sciences (GILD) 9.2 $196M 2.1M 94.26
Biogen Idec (BIIB) 5.2 $111M 327k 339.45
Alexion Pharmaceuticals 4.1 $88M 477k 185.03
Vertex Pharmaceuticals Incorporated (VRTX) 3.9 $83M 702k 118.80
Regeneron Pharmaceuticals (REGN) 3.8 $81M 199k 410.25
Actavis 3.4 $72M 278k 257.41
Incyte Corporation (INCY) 3.2 $69M 937k 73.11
Amgen (AMGN) 2.8 $61M 381k 159.29
Shire 2.8 $60M 282k 212.54
Mylan 2.7 $57M 1.0M 56.37
BioMarin Pharmaceutical (BMRN) 2.4 $52M 570k 90.40
Pfizer (PFE) 2.4 $51M 1.6M 31.15
Allergan 2.3 $49M 228k 212.59
Abbvie (ABBV) 1.8 $39M 594k 65.44
Johnson & Johnson (JNJ) 1.6 $34M 327k 104.57
Jazz Pharmaceuticals (JAZZ) 1.6 $33M 202k 163.73
Bristol Myers Squibb (BMY) 1.5 $32M 535k 59.03
Akorn 1.4 $31M 850k 36.20
Aetna 1.4 $30M 332k 88.83
Alkermes (ALKS) 1.2 $26M 437k 58.56
Teva Pharmaceutical Industries (TEVA) 1.1 $24M 424k 57.51
Neurocrine Biosciences (NBIX) 1.1 $22M 1.0M 22.34
NPS Pharmaceuticals 1.1 $22M 626k 35.77
Catamaran 1.1 $22M 434k 51.75
Ventas (VTR) 1.0 $21M 293k 71.70
Synageva Biopharma 1.0 $21M 223k 92.79
Allscripts Healthcare Solutions (MDRX) 1.0 $21M 1.6M 12.77
Illumina (ILMN) 0.9 $19M 104k 184.58
Molina Healthcare (MOH) 0.9 $19M 348k 53.53
Endo International (ENDPQ) 0.8 $18M 252k 72.12
iShares NASDAQ Biotechnology Index (IBB) 0.8 $18M 58k 303.35
Physicians Realty Trust 0.7 $16M 958k 16.60
Thermo Fisher Scientific (TMO) 0.7 $15M 121k 125.29
Omega Healthcare Investors (OHI) 0.7 $15M 376k 39.07
McKesson Corporation (MCK) 0.7 $14M 68k 207.58
Medical Properties Trust (MPW) 0.6 $14M 979k 13.78
Health Care Reit Pfd I 6.5% 0.6 $13M 200k 65.85
Eli Lilly & Co. (LLY) 0.6 $13M 187k 68.99
Momenta Pharmaceuticals 0.6 $13M 1.1M 12.04
Sabra Health Care REIT (SBRA) 0.6 $12M 408k 30.37
Ironwood Pharmaceuticals (IRWD) 0.6 $12M 768k 15.32
Celladon 0.6 $12M 607k 19.53
Alere 0.5 $11M 298k 38.00
Acorda Therapeutics 0.5 $11M 273k 40.87
Impax Laboratories 0.5 $11M 345k 31.68
Hca Holdings (HCA) 0.5 $11M 148k 73.39
Verastem 0.5 $11M 1.1M 9.14
Perrigo Company (PRGO) 0.5 $11M 63k 167.16
Sangamo Biosciences (SGMO) 0.5 $10M 679k 15.21
LTC Properties (LTC) 0.5 $10M 237k 43.17
Corsicanto Ltd conv bnd 0.4 $9.1M 15M 0.62
Stryker Corporation (SYK) 0.4 $9.0M 96k 94.33
Zimmer Holdings (ZBH) 0.4 $9.1M 80k 113.42
Senior Housing Properties Trust 0.4 $9.1M 410k 22.11
Heron Therapeutics (HRTX) 0.4 $8.8M 874k 10.06
IDEXX Laboratories (IDXX) 0.4 $8.3M 56k 148.26
Community Health Systems (CYH) 0.4 $8.3M 155k 53.92
Endologix 0.4 $8.4M 551k 15.29
St. Jude Medical 0.4 $8.0M 123k 65.03
CIGNA Corporation 0.4 $7.6M 74k 102.91
Infinity Pharmaceuticals (INFIQ) 0.3 $7.4M 439k 16.89
WellCare Health Plans 0.3 $7.3M 89k 82.06
Eleven Biotherapeutics 0.3 $6.5M 610k 10.69
Merrimack Pharmaceuticals In 0.3 $6.4M 568k 11.30
Centene Corporation (CNC) 0.3 $6.2M 60k 103.85
Ptc Therapeutics I (PTCT) 0.3 $6.2M 119k 51.77
Alnylam Pharmaceuticals (ALNY) 0.3 $6.0M 62k 97.00
Accuray Incorporated (ARAY) 0.3 $5.5M 732k 7.55
Agios Pharmaceuticals (AGIO) 0.2 $5.2M 46k 112.03
Karyopharm Therapeutics (KPTI) 0.2 $5.2M 138k 37.43
Sarepta Therapeutics (SRPT) 0.2 $5.0M 345k 14.47
Bluebird Bio (BLUE) 0.2 $5.0M 55k 91.72
Wright Medical 0.2 $4.2M 156k 26.87
Myriad Genetics (MYGN) 0.2 $3.8M 112k 34.06
Kythera Biopharmaceuticals I 0.2 $3.9M 111k 34.68
Ligand Pharmaceuticals In (LGND) 0.2 $3.7M 69k 53.21
BioDelivery Sciences International 0.2 $3.4M 283k 12.02
Supernus Pharmaceuticals note 7.500 5/0 0.2 $3.5M 2.0M 1.74
Intellipharmaceuticsintl Inc C 0.1 $3.2M 1.4M 2.26
Merrimack Pharmaceuticals In note 4.500% 7/1 0.1 $2.8M 1.5M 1.91
Receptos 0.1 $2.5M 20k 122.50
Dicerna Pharmaceuticals 0.1 $2.6M 156k 16.47
Sagent Pharmaceuticals 0.1 $2.1M 86k 25.11
Sorrento Therapeutics (SRNEQ) 0.1 $2.2M 214k 10.07
Bellicum Pharma 0.1 $1.4M 60k 23.03
Mei Pharma 0.1 $1.0M 244k 4.27
Zafgen 0.0 $821k 27k 30.85
Macrogenics (MGNX) 0.0 $447k 13k 35.08
OncoGenex Pharmaceuticals 0.0 $259k 113k 2.29
Sage Therapeutics (SAGE) 0.0 $183k 5.0k 36.60
Clovis Oncology 0.0 $3.0k 51.00 58.82