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Upstream Bio shares owned by Y-Intercept

Quarter-by-quarter ownership of Upstream Bio (UPB) shares owned by Y-Intercept from 13F filings

Historical chart of Y-Intercept investment in Upstream Bio

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All positions including Upstream Bio held by Y-Intercept consolidated in one spreadsheet with up to 7 years of data

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Quarterly reported holdings in Upstream Bio by Y-Intercept

Quarter filed	Position value	Share count	Share price at filing
2025-12-31	$1.3M	47k	27.15

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Top funds holding Upstream Bio

OrbiMed Advisors

Decheng Capital

Norges Bank Investment Management

Enavate Sciences GP

Altshuler Shaham

Bain Capital Life Sciences Investors

Omega Fund Management

State Street Corporation

Wellington Management Company

Geode Capital Management

View all funds holding Upstream Bio

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