Who owns UPSTREAM BIO INC COM?
- Ticker: UPB
- CUSIP Number: 91678a107
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Analyze quarterly positions in Upstream Bio with up to 7 years of data, all consolidated into one spreadsheet
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Top investors of Upstream Bio stock
Who bought or sold UPSTREAM BIO INC COM this quarter?
| Fund or Company Name | Shares Held | Valued At | Change in Shares | As Of | Actions |
|---|---|---|---|---|---|
| FMR | 7.5M | $204M | -7% | Dec 2025 |
|
| OrbiMed Advisors | 5.7M | $51M | 0% | Mar 2026 |
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| BlackRock | 3.4M | $30M | 1% | Mar 2026 |
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| Decheng Capital | 2.7M | $25M | -13% | Mar 2026 |
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| Enavate Sciences GP | 2.5M | $22M | 0% | Mar 2026 |
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| Vanguard Group | 2.4M | $65M | -2% | Dec 2025 |
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| Vanguard Capital Management | 1.9M | $17M | 100% | Mar 2026 |
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| Omega Fund Management | 1.3M | $36M | -2% | Dec 2025 |
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| State Street Corporation | 1.3M | $36M | 18% | Dec 2025 |
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| Y-Intercept | 1.0M | $9.0M | 2049% | Mar 2026 |
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| Federated Investors | 980k | $8.8M | 203169% | Mar 2026 |
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| Geode Capital Management | 951k | $8.6M | 12% | Mar 2026 |
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| Millennium Management | 937k | $8.4M | 81% | Mar 2026 |
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| Wellington Management Company | 895k | $24M | -20% | Dec 2025 |
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| SEB Asset Management AB | 879k | $7.9M | 100% | Mar 2026 |
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| Bain Capital Life Sciences Investors | 867k | $7.8M | -35% | Mar 2026 |
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| Parkman Healthcare Partners | 835k | $23M | -1% | Dec 2025 |
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| Woodline Partners | 832k | $7.5M | 9% | Mar 2026 |
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| D. E. Shaw & Co | 821k | $7.4M | 2929% | Mar 2026 |
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| Integral Health Asset Management | 750k | $20M | 30% | Dec 2025 |
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| Samsara BioCapital | 736k | $6.6M | 0% | Mar 2026 |
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| Pictet Asset Management Holding SA | 733k | $6.6M | -5% | Mar 2026 |
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| Vanguard Portfolio Management | 728k | $6.5M | 100% | Mar 2026 |
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| Hsbc Holdings | 640k | $5.8M | 100% | Mar 2026 |
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| Siren | 589k | $16M | -25% | Dec 2025 |
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| Morgan Stanley | 553k | $5.0M | 353% | Mar 2026 |
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| Barclays | 525k | $14M | 515% | Dec 2025 |
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| Nantahala Capital Management | 400k | $3.6M | -19% | Mar 2026 |
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| Altshuler Shaham | 380k | $3.4M | -72% | Mar 2026 |
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| Sphera Funds Management | 358k | $3.2M | 100% | Mar 2026 |
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| Marshall Wace | 344k | $9.3M | -60% | Dec 2025 |
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| Propel Bio Management | 342k | $3.1M | 100% | Mar 2026 |
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| Goldman Sachs Group | 317k | $2.8M | -5% | Mar 2026 |
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| Alyeska Investment Group | 298k | $2.7M | 0% | Mar 2026 |
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| Charles Schwab Investment Management | 285k | $7.7M | 0% | Dec 2025 |
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| Northern Trust | 237k | $6.4M | -7% | Dec 2025 |
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| UBS Group | 231k | $2.1M | -87% | Mar 2026 |
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| Vanguard Fiduciary Trust | 224k | $2.0M | 100% | Mar 2026 |
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| Point72 Asset Management | 190k | $1.7M | 1855% | Mar 2026 |
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| TCG Crossover Management | 181k | $1.6M | -76% | Mar 2026 |
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| Deutsche Bank Aktiengesellschaft | 181k | $1.6M | 42% | Mar 2026 |
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| Trexquant Investment | 177k | $1.6M | 469% | Mar 2026 |
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| Schonfeld Strategic Advisors | 161k | $1.5M | 39% | Mar 2026 |
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| Boxer Capital Management | 150k | $4.1M | 100% | Dec 2025 |
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| Bnp Paribas Arbitrage, Snc | 126k | $1.1M | 2432% | Mar 2026 |
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| Susquehanna International | 116k | $3.1M | 100% | Dec 2025 |
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| American Century Companies | 88k | $2.4M | 23% | Dec 2025 |
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| Bank of New York Mellon | 81k | $732k | -4% | Mar 2026 |
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| Dimensional Fund Advisors | 80k | $720k | 100% | Mar 2026 |
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| Citadel Advisors | 79k | $707k | 235% | Mar 2026 |
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| Simplify Asset Management | 78k | $700k | 100% | Mar 2026 |
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| Nuveen | 76k | $680k | -4% | Mar 2026 |
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| AQR Capital Management | 72k | $650k | 137% | Mar 2026 |
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| Exome Asset Management | 65k | $1.8M | 25% | Dec 2025 |
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| Quantinno Capital Management | 49k | $445k | 220% | Mar 2026 |
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| Bank of America Corporation | 49k | $436k | 100% | Mar 2026 |
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| Swiss National Bank | 48k | $433k | 81% | Mar 2026 |
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| Squarepoint Ops | 45k | $402k | 100% | Mar 2026 |
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| ALPS Advisors | 44k | $396k | -1% | Mar 2026 |
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| Rhumbline Advisers | 41k | $371k | -1% | Mar 2026 |
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| Invesco | 41k | $365k | -75% | Mar 2026 |
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| California State Teachers Retirement System | 40k | $357k | 171% | Mar 2026 |
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| GSA Capital Partners | 39k | $353k | 100% | Mar 2026 |
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| Rafferty Asset Management | 39k | $1.1M | 12% | Dec 2025 |
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| ADAR1 Capital Management | 35k | $315k | 100% | Mar 2026 |
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| Aquatic Capital Management | 32k | $283k | 100% | Mar 2026 |
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| Alliancebernstein | 31k | $842k | 0% | Mar 2026 |
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| Bleakley Financial Group | 29k | $260k | 100% | Mar 2026 |
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| Axq Capital | 28k | $248k | 100% | Mar 2026 |
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| Mariner Wealth Advisors | 27k | $246k | 131% | Mar 2026 |
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| Tudor Investment Corporation | 26k | $238k | 100% | Mar 2026 |
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| Martingale Asset Management | 26k | $236k | 100% | Mar 2026 |
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| DnB NOR Asset Management AS | 24k | $212k | 84% | Mar 2026 |
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| Man Group | 21k | $190k | 100% | Mar 2026 |
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| Diadema Partners | 21k | $557k | -90% | Dec 2025 |
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| MetLife Investment Advisors | 20k | $534k | -9% | Dec 2025 |
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| NISA Investment Advisors | 20k | $176k | 4790% | Mar 2026 |
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| Wells Fargo & Company | 18k | $166k | -50% | Mar 2026 |
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| Springbok Capital Management | 17k | $450k | 5% | Dec 2025 |
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| Renaissance Technologies | 16k | $445k | 100% | Dec 2025 |
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| Mirae Asset Global Etfs Holdings | 16k | $141k | -11% | Mar 2026 |
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| Manufacturers Life Insurance Company | 15k | $138k | 51% | Mar 2026 |
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| Jane Street | 15k | $138k | 100% | Mar 2026 |
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| XTX Topco | 15k | $410k | 100% | Dec 2025 |
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| Franklin Resources | 15k | $131k | 100% | Mar 2026 |
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| Vanguard Global Advisers | 13k | $118k | 100% | Mar 2026 |
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| Virtu Financial | 12k | $332k | 100% | Dec 2025 |
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| CI Private Wealth | 12k | $109k | 100% | Mar 2026 |
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| Verition Fund Management | 12k | $326k | -74% | Dec 2025 |
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| Creative Planning | 11k | $98k | -8% | Mar 2026 |
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| Shay Capital | 10k | $90k | 100% | Mar 2026 |
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| Virtus Investment Advisers | 9.8k | $266k | 0% | Dec 2025 |
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| OTR - Nominee Name for The State Teachers Retirement Board of Ohio | 9.8k | $88k | 0% | Mar 2026 |
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| Legal & General Group | 9.6k | $87k | -30% | Mar 2026 |
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| China Universal Asset Management | 9.6k | $86k | 9% | Mar 2026 |
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| Police & Firemen's Retirement System of New Jersey | 9.5k | $85k | 0% | Mar 2026 |
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| Vanguard Asset Management | 9.3k | $83k | 100% | Mar 2026 |
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| Klp Kapitalforvaltning As | 5.9k | $53k | 103% | Mar 2026 |
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| Persistent Asset Partners | 5.5k | $50k | -38% | Mar 2026 |
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| Citigroup | 5.1k | $46k | 100% | Mar 2026 |
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| Vanguard Investments Australia | 4.1k | $37k | 100% | Mar 2026 |
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| Russell Investments | 3.6k | $33k | 29% | Mar 2026 |
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| CWM | 3.4k | $91k | 1% | Dec 2025 |
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| Wellington Grp | 3.0k | $27k | 50% | Mar 2026 |
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| Mirae Asset Global Investments | 2.8k | $25k | 7% | Mar 2026 |
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| Summit Investment Advisors | 2.7k | $25k | 0% | Mar 2026 |
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| Gf Fund Management | 1.2k | $11k | 13% | Mar 2026 |
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| Sterling Capital Management | 1.1k | $9.8k | -43% | Mar 2026 |
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| Versant Capital Management | 762.00 | $6.9k | 37% | Mar 2026 |
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| Rockefeller Capital Management | 738.00 | $6.6k | 100% | Mar 2026 |
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| GAMMA Investing | 715.00 | $6.4k | -21% | Mar 2026 |
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| Tower Research Capital | 669.00 | $18k | -64% | Dec 2025 |
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| Quantbot Technologies | 663.00 | $6.0k | 100% | Mar 2026 |
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| Ubs Global Asset Management Americas | 588.00 | $5.3k | 143% | Mar 2026 |
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| Us Bancorp | 546.00 | $15k | 3% | Dec 2025 |
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| Zurcher Kantonalbank | 477.00 | $4.3k | 100% | Mar 2026 |
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| Simplex Trading | 466.00 | $13k | 100% | Dec 2025 |
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| Essential Partners | 402.00 | $3.6k | 314% | Mar 2026 |
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| Global Retirement Partners | 273.00 | $7.4k | -18% | Dec 2025 |
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| EverSource Wealth Advisors | 222.00 | $2.0k | -21% | Mar 2026 |
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| MAI Wealth Advisors | 171.00 | $1.5k | 100% | Mar 2026 |
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| Torren Management | 162.00 | $1.5k | 100% | Mar 2026 |
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| N.E.W. Advisory Services | 120.00 | $1.1k | 100% | Mar 2026 |
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| New York State Common Retirement Fund | 100.00 | $900.000000 | -99% | Mar 2026 |
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| Wealth Preservation Advisors | 86.00 | $774.000000 | 100% | Mar 2026 |
|
| Farther Finance Advisors | 81.00 | $753.996600 | 100% | Mar 2026 |
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| SRS Capital Advisors | 77.00 | $693.000000 | 3750% | Mar 2026 |
|
| Hanson McClain Advisors | 68.00 | $1.8k | 1% | Dec 2025 |
|
| Signature | 66.00 | $594.000000 | -44% | Mar 2026 |
|
| Rothschild Investment | 61.00 | $549.000000 | 6000% | Mar 2026 |
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| Ameritas Advisory Services | 31.00 | $279.000000 | 100% | Mar 2026 |
|
| SageView Advisory Group | 30.00 | $815.001000 | 100% | Dec 2025 |
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| Caitong International Asset Management | 23.00 | $207.000000 | 100% | Mar 2026 |
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| Root Financial Partners | 20.00 | $180.000000 | 100% | Mar 2026 |
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| Larson Financial Group | 14.00 | $380.000600 | 100% | Dec 2025 |
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| Advisor Group Holdings | 5.00 | $136.000000 | 100% | Dec 2025 |
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| Covestor | 4.00 | $0 | 100% | Mar 2026 |
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| SJS Investment Consulting | 2.00 | $18.000000 | 100% | Mar 2026 |
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| Parallel Advisors | 2.00 | $18.000000 | 0% | Mar 2026 |
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| IFP Advisors | 1.00 | $9.000000 | 0% | Mar 2026 |
|
| Freestone Grove Partners | 1.00 | $9.000000 | 100% | Mar 2026 |
|
Who sold out of Upstream Bio?
| Fund or Company Name | Date Sold | Shares Held | Valued At |
|---|---|---|---|
| Norges Bank Investment Management | Dec 2025 | 2.9M | $78M |
| VR Adviser | Dec 2025 | 1.2M | $32M |
| Vestal Point Capital | Dec 2025 | 720k | $20M |
| Dr. Jeffrey R. Jay, M.D. | Dec 2025 | 300k | $8.1M |
| Jennison Associates | Dec 2025 | 289k | $7.8M |
| SummitTX Capital | Dec 2025 | 117k | $3.2M |
| Caption Management | Sep 2025 | 88k | $1.7M |
| ExodusPoint Capital Management | Dec 2025 | 75k | $2.0M |
| Artia Global Partners | Dec 2025 | 69k | $1.9M |
| Ameriprise Financial | Dec 2025 | 57k | $1.5M |
| Seven Grand Managers | Dec 2025 | 50k | $1.4M |
| Jpmorgan Chase & Co | Sep 2025 | 30k | $563k |
| Sig Brokerage | Sep 2025 | 20k | $376k |
| PSP Research | Dec 2025 | 18k | $479k |
| ProFund Advisors | Dec 2025 | 15k | $396k |
| Graham Capital Management | Dec 2025 | 14k | $372k |
| Two Sigma Investments | Dec 2025 | 11k | $285k |
| Intech Investment Management | Dec 2025 | 10k | $282k |
| ProShare Advisors | Dec 2025 | 8.4k | $227k |
| Sei Investments | Dec 2025 | 8.1k | $220k |
| SG Americas Securities | Dec 2025 | 5.5k | $150k |
| Amalgamated Bank | Dec 2025 | 1.0k | $28k |
| Royal Bank of Canada | Sep 2025 | 832.00 | $17k |
| Aster Capital Management | Dec 2025 | 271.00 | $7.4k |
| Daiwa Securities Group | Dec 2025 | 180.00 | $5.0k |
| J.Safra Asset Management | Dec 2025 | 128.00 | $3.5k |
| Pnc Financial Services | Dec 2025 | 106.00 | $2.9k |
| Sunbelt Securities | Dec 2025 | 19.00 | $516.000100 |