Baker Bros. Advisors

Baker Bros. Advisors as of March 31, 2013

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 71 positions in its portfolio as reported in the March 2013 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Synergy Pharmaceuticals 3.0 $9.9M 1.6M 6.07
Chelsea Therapeutics International 2.9 $9.7M 4.8M 2.04
Medivation 2.625% 4/1/17 conv bonds 2.7 $9.1M 40M 0.23
Gilead Sciences (GILD) 2.7 $9.0M 184k 48.94
Exelisis 4.25% 8/15/2019 conv bonds 2.7 $8.9M 19M 0.47
Ariad Pharmaceuticals 2.6 $8.9M 2.2M 4.13
Cerus 2.6 $8.9M 6.5M 1.36
Biomarin Pharmaceuticals 2.6 $8.8M 783k 11.19
Clovis Oncology 2.6 $8.7M 1.0M 8.69
Pharmacyclics 2.5 $8.4M 11M 0.77
23 Halozyme Therapeutics 2.5 $8.3M 3.2M 2.62
Vanda Pharmaceuticals (VNDA) 2.3 $7.6M 1.9M 3.92
55 Intermune Inc Notes 5% 3/1/15 conv bonds 2.3 $7.6M 17M 0.45
XenoPort 2.2 $7.4M 1.0M 7.15
Array BioPharma 2.2 $7.4M 1.5M 4.91
Threshold Pharma 2.2 $7.4M 1.6M 4.61
BioDelivery Sciences International 2.1 $7.2M 1.7M 4.21
Infinity Pharmaceuticals 2.1 $7.1M 1.2M 6.04
Incyte 2.0 $6.7M 15M 0.45
Gilead 1.625% 5/1/16 conv bonds 2.0 $6.7M 22M 0.31
BioCryst Pharmaceuticals (BCRX) 2.0 $6.6M 5.6M 1.19
Synageva Biopharma 1.9 $6.5M 9.2M 0.71
Auxilium 1.9 $6.5M 2.1M 3.06
Derma Sciences 1.9 $6.4M 1.4M 4.72
Repros Therapeutics 1.9 $6.4M 2.3M 2.83
Insmed (INSM) 1.8 $6.0M 796k 7.49
Seattle Genetics 1.8 $6.0M 19M 0.31
Intermune 1.7 $5.7M 1.7M 3.29
D Stemline Therapeutics 1.7 $5.7M 500k 11.41
Genomic Health 1.7 $5.7M 13M 0.45
Anacor Pharmaceuticals 1.5 $5.0M 777k 6.46
Medivation 1.5 $5.0M 535k 9.37
Progenics Pharmaceuticals 1.4 $4.8M 900k 5.38
Aegerion Pharmaceuticals 1.4 $4.8M 864k 5.61
United Therapeutics Notes 1% 9/15/16 144a conv bonds 1.4 $4.7M 18M 0.26
Viropharma 1.4 $4.6M 8.5M 0.54
Mei Pharma 1.3 $4.3M 500k 8.63
Onyx Pharmaceuticals 1.2 $4.2M 160k 26.23
Acadia Pharmaceuticals 1.2 $4.1M 16M 0.26
Kythera Biopharmaceuticals I 1.2 $4.0M 165k 24.36
Intercept Pharmaceuticals In 1.2 $4.0M 375k 10.73
Achillion Pharmaceuticals 1.2 $4.0M 455k 8.75
Gilead 0.625% 5/1/13 conv bonds 1.2 $4.0M 25M 0.16
Vertex Pharmaceuticals 1.1 $3.9M 252k 15.35
AVEO Pharmaceuticals 1.1 $3.8M 520k 7.35
54 Intermune Inc Notes 2.5% 9/15/18 conv bonds 1.1 $3.8M 17M 0.23
INC Ventrus Biosciences 1.1 $3.6M 1.2M 2.99
Zogenix 1.1 $3.6M 2.0M 1.80
Qlt 1.1 $3.6M 1.5M 2.33
Ironwood Pharmaceuticals 0.8 $2.8M 698k 3.96
Cytrx 0.8 $2.7M 1.0M 2.72
Synta Pharmaceuticals 0.8 $2.6M 1.5M 1.76
Intermune Inc Notes 2.5% 12/15/17 conv bonds 0.7 $2.5M 41M 0.06
ArQule 0.7 $2.4M 910k 2.59
Salix Pharmaceuticals 0.7 $2.2M 44k 51.17
Ligand Pharmaceuticals 0.6 $2.0M 73k 26.65
Discovery Laboratories 0.6 $2.0M 853k 2.29
Amicus Therapeutics (FOLD) 0.5 $1.6M 515k 3.17
Biodel 0.5 $1.5M 540k 2.84
Prothena (PRTA) 0.4 $1.3M 192k 6.69
Questcor Pharmaceuticals 0.3 $1.1M 342k 3.26
Geron Corporation (GERN) 0.3 $1.1M 1.0M 1.07
Lpath 0.3 $1.0M 200k 5.02
Biomarin Pharmaceuticals Notes 1.875% 4/23/2017 conv bonds 0.3 $916k 23M 0.04
Xoma 0.2 $811k 20M 0.04
Chemocentryx 0.2 $691k 50k 13.82
Tesaro 0.2 $686k 31k 21.97
ZIOPHARM Oncology 0.1 $465k 254k 1.83
Cubist Pharmaceuticals 0.1 $234k 5.0k 46.80
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.1 $207k 21k 9.87
Aradigm Corporation (ARDM) 0.0 $13k 100k 0.13