Baker Bros. Advisors as of Sept. 30, 2021
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 122 positions in its portfolio as reported in the September 2021 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 35.3 | $8.0B | 47M | 169.80 | |
| BeiGene Sponsored Adr (BGNE) | 18.6 | $4.2B | 12M | 363.00 | |
| Incyte Corporation (INCY) | 9.7 | $2.2B | 32M | 68.78 | |
| Kodiak Sciences (KOD) | 6.2 | $1.4B | 15M | 95.98 | |
| Ascendis Pharma A/S Sponsored Adr (ASND) | 3.2 | $724M | 4.5M | 159.39 | |
| ACADIA Pharmaceuticals (ACAD) | 3.1 | $696M | 42M | 16.61 | |
| BioMarin Pharmaceutical (BMRN) | 2.6 | $589M | 7.6M | 77.29 | |
| argenx SE Sponsored Adr (ARGX) | 1.5 | $338M | 1.1M | 302.00 | |
| Prelude Therapeutics (PRLD) | 1.4 | $316M | 10M | 31.25 | |
| Invitae (NVTAQ) | 1.2 | $281M | 9.9M | 28.43 | |
| Mirati Therapeutics | 1.1 | $249M | 1.4M | 176.91 | |
| Abcellera Biologics (ABCL) | 0.9 | $209M | 11M | 20.04 | |
| Igm Biosciences (IGMS) | 0.9 | $208M | 3.2M | 65.76 | |
| BioCryst Pharmaceuticals (BCRX) | 0.8 | $183M | 13M | 14.37 | |
| Kymera Therapeutics (KYMR) | 0.6 | $140M | 2.4M | 58.74 | |
| Pacific Biosciences of California (PACB) | 0.6 | $139M | 5.4M | 25.55 | |
| Madrigal Pharmaceuticals (MDGL) | 0.5 | $120M | 1.5M | 79.79 | |
| Legend Biotech Corporation Sponsored Ads (LEGN) | 0.5 | $120M | 2.4M | 50.56 | |
| Amarin Corporation Sponsored Adr (AMRN) | 0.5 | $112M | 22M | 5.10 | |
| Immunocore Holdings Ads (IMCR) | 0.4 | $93M | 2.5M | 37.07 | |
| Heron Therapeutics (HRTX) | 0.4 | $87M | 8.1M | 10.69 | |
| Cerus Corporation (CERS) | 0.4 | $84M | 14M | 6.09 | |
| Global Blood Therapeutics In | 0.4 | $82M | 3.2M | 25.48 | |
| Allakos (ALLK) | 0.3 | $74M | 703k | 105.87 | |
| Nurix Therapeutics (NRIX) | 0.3 | $74M | 2.5M | 29.96 | |
| DBV Technologies Sponsored Adr (DBVT) | 0.3 | $72M | 15M | 4.90 | |
| Instil Bio | 0.3 | $70M | 3.9M | 17.88 | |
| Verve Therapeutics (VERV) | 0.3 | $67M | 1.4M | 47.00 | |
| Verastem | 0.3 | $66M | 22M | 3.08 | |
| Horizon Therapeutics Public SHS | 0.3 | $66M | 599k | 109.54 | |
| Neurocrine Biosciences (NBIX) | 0.3 | $65M | 677k | 95.91 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.3 | $59M | 2.2M | 27.54 | |
| Immatics SHS (IMTX) | 0.3 | $58M | 4.4M | 13.00 | |
| Apellis Pharmaceuticals Note 3.5% 9/15/2026 (Principal) | 0.3 | $57M | 47M | 1.22 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.2 | $51M | 9.8M | 5.17 | |
| Rhythm Pharmaceuticals (RYTM) | 0.2 | $51M | 3.9M | 13.06 | |
| Zymeworks | 0.2 | $50M | 1.7M | 29.04 | |
| Travere Therapeutics (TVTX) | 0.2 | $50M | 2.0M | 24.25 | |
| Bluebird Bio (BLUE) | 0.2 | $48M | 2.5M | 19.11 | |
| Talis Biomedical Corp | 0.2 | $47M | 7.6M | 6.25 | |
| Forma Therapeutics Holdings SHS | 0.2 | $47M | 2.0M | 23.19 | |
| Merus N V (MRUS) | 0.2 | $45M | 2.0M | 22.00 | |
| Insmed Incorporated Note 0.75% 6/1/2028 (Principal) | 0.2 | $44M | 40M | 1.10 | |
| Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) | 0.2 | $43M | 29M | 1.48 | |
| Ultragenyx Pharmaceutical (RARE) | 0.2 | $40M | 444k | 90.19 | |
| Alkermes SHS (ALKS) | 0.2 | $38M | 1.2M | 30.84 | |
| Fulgent Genetics (FLGT) | 0.2 | $36M | 401k | 89.95 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $35M | 1.7M | 20.98 | |
| Aligos Therapeutics (ALGS) | 0.1 | $32M | 2.1M | 15.51 | |
| Kiniksa Pharmaceuticals Com Cl A (KNSA) | 0.1 | $32M | 2.8M | 11.39 | |
| Krystal Biotech (KRYS) | 0.1 | $32M | 608k | 52.21 | |
| Tricida Note 3.5% 5/15/2027 (Principal) | 0.1 | $31M | 75M | 0.42 | |
| Neoleukin Therapeutics | 0.1 | $28M | 3.8M | 7.23 | |
| Aeglea Biotherapeutics | 0.1 | $27M | 3.4M | 7.95 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $27M | 3.4M | 8.00 | |
| Bioatla (BCAB) | 0.1 | $24M | 825k | 29.44 | |
| Chinook Therapeutics | 0.1 | $24M | 1.9M | 12.76 | |
| Novavax (NVAX) | 0.1 | $23M | 109k | 207.31 | |
| Reata Pharmaceuticals Cl A | 0.1 | $23M | 224k | 100.61 | |
| Atreca Cl A Com (BCEL) | 0.1 | $22M | 3.5M | 6.23 | |
| Design Therapeutics (DSGN) | 0.1 | $21M | 1.4M | 14.69 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.1 | $20M | 2.6M | 7.79 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.1 | $19M | 921k | 21.05 | |
| Dice Therapeutics | 0.1 | $19M | 588k | 32.75 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.1 | $19M | 1.1M | 16.70 | |
| Axsome Therapeutics (AXSM) | 0.1 | $18M | 539k | 32.96 | |
| Surrozen | 0.1 | $18M | 2.5M | 7.08 | |
| Otonomy | 0.1 | $15M | 7.7M | 1.92 | |
| Cyteir Therapeutics | 0.1 | $14M | 813k | 17.55 | |
| Mirum Pharmaceuticals (MIRM) | 0.1 | $13M | 647k | 19.92 | |
| Albireo Pharma | 0.1 | $13M | 413k | 31.20 | |
| Invitae Corporation Note 2.0% 9/1/2024 (Principal) | 0.1 | $13M | 10M | 1.22 | |
| Altimmune (ALT) | 0.1 | $12M | 1.1M | 11.31 | |
| Tscan Therapeutics (TCRX) | 0.1 | $12M | 1.4M | 8.34 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $12M | 427k | 27.12 | |
| Aurinia Pharmaceuticals (AUPH) | 0.1 | $12M | 521k | 22.13 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $12M | 752k | 15.28 | |
| Tango Therapeutics (TNGX) | 0.0 | $9.7M | 750k | 12.93 | |
| Macrogenics (MGNX) | 0.0 | $9.3M | 443k | 20.94 | |
| Karuna Therapeutics Ord | 0.0 | $8.6M | 70k | 122.33 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $8.3M | 500k | 16.60 | |
| Cabaletta Bio (CABA) | 0.0 | $8.1M | 662k | 12.16 | |
| Cymabay Therapeutics | 0.0 | $7.9M | 2.2M | 3.65 | |
| Athira Pharma (ATHA) | 0.0 | $7.6M | 806k | 9.38 | |
| Genetron Holdings Ads | 0.0 | $6.3M | 455k | 13.85 | |
| Biomea Fusion (BMEA) | 0.0 | $6.3M | 525k | 11.97 | |
| Amryt Pharma Sponsored Adr | 0.0 | $6.2M | 518k | 12.05 | |
| Ngm Biopharmaceuticals (NGM) | 0.0 | $6.1M | 292k | 21.02 | |
| Revolution Medicines (RVMD) | 0.0 | $6.1M | 222k | 27.51 | |
| Kura Oncology (KURA) | 0.0 | $5.7M | 304k | 18.73 | |
| Atyr Pharma (LIFE) | 0.0 | $5.7M | 625k | 9.08 | |
| Alector (ALEC) | 0.0 | $5.5M | 239k | 22.82 | |
| Relmada Therapeutics (RLMD) | 0.0 | $5.3M | 201k | 26.21 | |
| Chemocentryx | 0.0 | $5.2M | 301k | 17.10 | |
| Tricida | 0.0 | $4.8M | 1.0M | 4.64 | |
| Harmony Biosciences Hldgs In (HRMY) | 0.0 | $4.7M | 124k | 38.33 | |
| BioMarin Pharmaceutical Note 0.599% 8/1/2024 (Principal) | 0.0 | $4.6M | 4.5M | 1.02 | |
| Replimune Group (REPL) | 0.0 | $4.6M | 154k | 29.64 | |
| Denali Therapeutics (DNLI) | 0.0 | $4.5M | 89k | 50.45 | |
| Neximmune | 0.0 | $4.5M | 294k | 15.14 | |
| Hookipa Pharma Inc equity (HOOK) | 0.0 | $4.1M | 701k | 5.89 | |
| Iteos Therapeutics (ITOS) | 0.0 | $4.1M | 150k | 27.00 | |
| Vincera Pharma (VINC) | 0.0 | $3.9M | 241k | 16.17 | |
| Acceleron Pharma | 0.0 | $3.9M | 22k | 172.09 | |
| Burning Rock Biotech Sponsored Ads (BNR) | 0.0 | $3.7M | 209k | 17.88 | |
| Akero Therapeutics (AKRO) | 0.0 | $2.6M | 118k | 22.35 | |
| Gamida Cell SHS (GMDA) | 0.0 | $2.4M | 611k | 3.92 | |
| Leap Therapeutics | 0.0 | $2.2M | 560k | 4.01 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $2.2M | 202k | 11.11 | |
| Syndax Pharmaceuticals (SNDX) | 0.0 | $2.1M | 111k | 19.11 | |
| Logicbio Therapeutics | 0.0 | $2.1M | 452k | 4.58 | |
| Evofem Biosciences | 0.0 | $2.0M | 2.7M | 0.74 | |
| Tcr2 Therapeutics Inc cs | 0.0 | $1.5M | 177k | 8.51 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $1.4M | 200k | 6.92 | |
| Inozyme Pharma (INZY) | 0.0 | $1.2M | 107k | 11.59 | |
| Kezar Life Sciences (KZR) | 0.0 | $1.2M | 140k | 8.64 | |
| Passage Bio (PASG) | 0.0 | $1.2M | 117k | 9.96 | |
| Affimed Therapeutics B V | 0.0 | $1.0M | 165k | 6.18 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $950k | 833k | 1.14 | |
| Oyster Point Pharma | 0.0 | $728k | 61k | 11.85 | |
| Bellicum Pharmaceuticals | 0.0 | $727k | 249k | 2.92 | |
| Mereo BioPharma Group Ads (MREO) | 0.0 | $708k | 293k | 2.42 |
