Baker Bros. Advisors as of March 31, 2022
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 118 positions in its portfolio as reported in the March 2022 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 38.8 | $6.8B | 47M | 144.05 | |
| Incyte Corporation (INCY) | 16.5 | $2.9B | 36M | 79.42 | |
| BeiGene Sponsored Adr (BGNE) | 12.6 | $2.2B | 12M | 188.60 | |
| ACADIA Pharmaceuticals (ACAD) | 5.8 | $1.0B | 42M | 24.22 | |
| BioMarin Pharmaceutical (BMRN) | 3.4 | $588M | 7.6M | 77.10 | |
| Ascendis Pharma A/S Sponsored Adr (ASND) | 3.1 | $533M | 4.5M | 117.36 | |
| argenx SE Sponsored Adr (ARGX) | 2.0 | $353M | 1.1M | 315.31 | |
| BioCryst Pharmaceuticals (BCRX) | 1.2 | $207M | 13M | 16.26 | |
| Madrigal Pharmaceuticals (MDGL) | 0.8 | $147M | 1.5M | 98.12 | |
| Kodiak Sciences (KOD) | 0.7 | $123M | 16M | 7.72 | |
| Mirati Therapeutics | 0.7 | $116M | 1.4M | 82.22 | |
| Global Blood Therapeutics In | 0.7 | $115M | 3.3M | 34.64 | |
| Abcellera Biologics (ABCL) | 0.6 | $102M | 11M | 9.75 | |
| Kymera Therapeutics (KYMR) | 0.6 | $101M | 2.4M | 42.32 | |
| Horizon Therapeutics Public SHS | 0.5 | $95M | 899k | 105.21 | |
| Travere Therapeutics (TVTX) | 0.5 | $85M | 3.3M | 25.77 | |
| Igm Biosciences (IGMS) | 0.5 | $84M | 3.2M | 26.73 | |
| Invitae (NVTAQ) | 0.5 | $79M | 9.9M | 7.97 | |
| Immunocore Holdings Ads (IMCR) | 0.4 | $75M | 2.5M | 29.90 | |
| Cerus Corporation (CERS) | 0.4 | $75M | 14M | 5.49 | |
| Legend Biotech Corporation Sponsored Ads (LEGN) | 0.4 | $73M | 2.0M | 36.34 | |
| Prelude Therapeutics (PRLD) | 0.4 | $70M | 10M | 6.90 | |
| Amarin Corporation Sponsored Adr (AMRN) | 0.4 | $70M | 21M | 3.29 | |
| Neurocrine Biosciences (NBIX) | 0.4 | $64M | 677k | 93.75 | |
| Merus N V (MRUS) | 0.3 | $54M | 2.0M | 26.44 | |
| Krystal Biotech (KRYS) | 0.3 | $54M | 808k | 66.54 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.3 | $51M | 2.2M | 23.50 | |
| Pacific Biosciences of California (PACB) | 0.3 | $50M | 5.4M | 9.10 | |
| Rhythm Pharmaceuticals (RYTM) | 0.3 | $48M | 4.1M | 11.52 | |
| Heron Therapeutics (HRTX) | 0.3 | $47M | 8.1M | 5.72 | |
| Entrada Therapeutics (TRDA) | 0.3 | $44M | 4.7M | 9.39 | |
| Instil Bio | 0.2 | $42M | 3.9M | 10.75 | |
| Alkermes SHS (ALKS) | 0.2 | $40M | 1.5M | 26.31 | |
| Insmed Incorporated Note 0.75% 6/1/2028 (Principal) | 0.2 | $39M | 40M | 0.97 | |
| Sarepta Therapeutics DBCV 1.5% 11/15/2024 (Principal) | 0.2 | $38M | 29M | 1.31 | |
| Chinook Therapeutics | 0.2 | $38M | 2.3M | 16.36 | |
| Verastem | 0.2 | $38M | 27M | 1.41 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $38M | 2.1M | 18.33 | |
| Immatics SHS (IMTX) | 0.2 | $35M | 4.4M | 7.99 | |
| 2seventy bio Common Stock (TSVT) | 0.2 | $35M | 2.1M | 17.06 | |
| Nurix Therapeutics (NRIX) | 0.2 | $34M | 2.5M | 14.01 | |
| Verve Therapeutics (VERV) | 0.2 | $32M | 1.4M | 22.82 | |
| Ultragenyx Pharmaceutical (RARE) | 0.2 | $32M | 444k | 72.62 | |
| Kiniksa Pharmaceuticals Com Cl A (KNSA) | 0.2 | $28M | 2.8M | 9.94 | |
| Replimune Group (REPL) | 0.2 | $27M | 1.6M | 16.98 | |
| Axsome Therapeutics (AXSM) | 0.1 | $25M | 611k | 41.39 | |
| DBV Technologies Sponsored Adr (DBVT) | 0.1 | $23M | 15M | 1.59 | |
| Design Therapeutics (DSGN) | 0.1 | $23M | 1.4M | 16.15 | |
| Chemocentryx | 0.1 | $23M | 917k | 25.07 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $23M | 752k | 30.57 | |
| Affimed Therapeutics B V | 0.1 | $23M | 5.2M | 4.37 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.1 | $20M | 9.8M | 2.06 | |
| Forma Therapeutics Holdings SHS | 0.1 | $19M | 2.0M | 9.30 | |
| Otonomy | 0.1 | $19M | 7.8M | 2.40 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $19M | 2.7M | 6.86 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.1 | $18M | 828k | 21.95 | |
| Tricida | 0.1 | $14M | 1.7M | 8.22 | |
| Relmada Therapeutics (RLMD) | 0.1 | $13M | 495k | 26.99 | |
| Fulgent Genetics (FLGT) | 0.1 | $13M | 201k | 62.41 | |
| Bluebird Bio (BLUE) | 0.1 | $12M | 2.5M | 4.85 | |
| Dice Therapeutics | 0.1 | $11M | 588k | 19.13 | |
| Atreca Cl A Com (BCEL) | 0.1 | $11M | 3.5M | 3.17 | |
| Zymeworks | 0.1 | $11M | 1.7M | 6.55 | |
| Athira Pharma (ATHA) | 0.1 | $11M | 806k | 13.50 | |
| Talis Biomedical Corp | 0.1 | $11M | 7.6M | 1.41 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $11M | 427k | 24.74 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.1 | $10M | 1.1M | 8.97 | |
| Sarepta Therapeutics (SRPT) | 0.1 | $9.6M | 124k | 78.12 | |
| Karuna Therapeutics Ord | 0.1 | $8.9M | 70k | 126.79 | |
| Invitae Corporation Note 2.0% 9/1/2024 (Principal) | 0.0 | $8.4M | 10M | 0.81 | |
| Aeglea Biotherapeutics | 0.0 | $7.8M | 3.4M | 2.30 | |
| Vera Therapeutics Cl A (VERA) | 0.0 | $7.8M | 333k | 23.49 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $7.6M | 2.6M | 2.94 | |
| Surrozen | 0.0 | $7.5M | 2.5M | 3.01 | |
| Reata Pharmaceuticals Cl A | 0.0 | $7.3M | 224k | 32.76 | |
| Neoleukin Therapeutics | 0.0 | $7.2M | 3.8M | 1.88 | |
| Fibrogen (FGEN) | 0.0 | $7.0M | 582k | 12.02 | |
| Biomea Fusion (BMEA) | 0.0 | $6.9M | 1.6M | 4.46 | |
| Cymabay Therapeutics | 0.0 | $6.7M | 2.2M | 3.11 | |
| Altimmune (ALT) | 0.0 | $6.5M | 1.1M | 6.09 | |
| Harmony Biosciences Hldgs In (HRMY) | 0.0 | $6.0M | 124k | 48.65 | |
| Tango Therapeutics (TNGX) | 0.0 | $5.7M | 750k | 7.58 | |
| Revolution Medicines (RVMD) | 0.0 | $5.7M | 222k | 25.51 | |
| Hookipa Pharma Inc equity (HOOK) | 0.0 | $5.5M | 2.4M | 2.28 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $4.9M | 500k | 9.70 | |
| Iteos Therapeutics (ITOS) | 0.0 | $4.8M | 150k | 32.18 | |
| Aligos Therapeutics (ALGS) | 0.0 | $4.5M | 2.1M | 2.15 | |
| Ngm Biopharmaceuticals (NGM) | 0.0 | $4.4M | 292k | 15.25 | |
| Kura Oncology (KURA) | 0.0 | $4.4M | 275k | 16.08 | |
| Bioatla (BCAB) | 0.0 | $4.1M | 825k | 5.00 | |
| Allakos (ALLK) | 0.0 | $4.0M | 703k | 5.70 | |
| Tscan Therapeutics (TCRX) | 0.0 | $4.0M | 1.4M | 2.80 | |
| Macrogenics (MGNX) | 0.0 | $3.9M | 443k | 8.81 | |
| Novavax (NVAX) | 0.0 | $3.5M | 48k | 73.66 | |
| Alector (ALEC) | 0.0 | $3.4M | 239k | 14.25 | |
| Atyr Pharma (LIFE) | 0.0 | $3.3M | 625k | 5.35 | |
| Cyteir Therapeutics | 0.0 | $3.1M | 813k | 3.77 | |
| Denali Therapeutics (DNLI) | 0.0 | $2.9M | 89k | 32.17 | |
| Kezar Life Sciences (KZR) | 0.0 | $2.3M | 140k | 16.62 | |
| Tcr2 Therapeutics Inc cs | 0.0 | $2.1M | 753k | 2.76 | |
| Burning Rock Biotech Sponsored Ads (BNR) | 0.0 | $1.9M | 209k | 9.29 | |
| Syndax Pharmaceuticals (SNDX) | 0.0 | $1.9M | 111k | 17.38 | |
| Akero Therapeutics (AKRO) | 0.0 | $1.7M | 118k | 14.19 | |
| Cabaletta Bio (CABA) | 0.0 | $1.3M | 662k | 2.03 | |
| Neximmune | 0.0 | $1.2M | 294k | 4.21 | |
| Epizyme | 0.0 | $1.2M | 1.0M | 1.15 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $1.0M | 200k | 5.11 | |
| Genetron Holdings Ads | 0.0 | $997k | 455k | 2.19 | |
| Leap Therapeutics | 0.0 | $979k | 560k | 1.75 | |
| Vincera Pharma (VINC) | 0.0 | $966k | 241k | 4.00 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $764k | 202k | 3.79 | |
| Oyster Point Pharma | 0.0 | $715k | 61k | 11.64 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $686k | 45k | 15.24 | |
| Bellicum Pharmaceuticals | 0.0 | $538k | 249k | 2.16 | |
| Inozyme Pharma (INZY) | 0.0 | $438k | 107k | 4.09 | |
| Passage Bio (PASG) | 0.0 | $363k | 117k | 3.10 | |
| Logicbio Therapeutics | 0.0 | $307k | 452k | 0.68 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $208k | 833k | 0.25 |
