Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2023

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 101 positions in its portfolio as reported in the September 2023 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seagen 54.5 $9.5B 45M 212.15
BeiGene Sponsored Adr (BGNE) 12.1 $2.1B 12M 179.87
Incyte Corporation (INCY) 12.0 $2.1B 36M 57.77
ACADIA Pharmaceuticals (ACAD) 5.1 $893M 43M 20.84
BioMarin Pharmaceutical (BMRN) 1.9 $337M 3.8M 88.48
Madrigal Pharmaceuticals (MDGL) 1.3 $226M 1.5M 146.04
Rhythm Pharmaceuticals (RYTM) 0.9 $154M 6.7M 22.93
Roivant Sciences SHS (ROIV) 0.8 $139M 12M 11.68
Immunocore Holdings Ads (IMCR) 0.8 $131M 2.5M 51.90
Invitae Corporation Note 1.5% 4/1/2028 (Principal) 0.8 $130M 300M 0.43
Akero Therapeutics (AKRO) 0.7 $120M 2.4M 50.58
Abcellera Biologics (ABCL) 0.6 $96M 21M 4.60
BioCryst Pharmaceuticals (BCRX) 0.5 $90M 13M 7.08
Replimune Group (REPL) 0.5 $78M 4.6M 17.11
Entrada Therapeutics (TRDA) 0.4 $77M 4.9M 15.80
Revolution Medicines (RVMD) 0.4 $75M 2.7M 27.68
argenx SE Sponsored Adr (ARGX) 0.4 $74M 151k 491.63
Springworks Therapeutics (SWTX) 0.4 $69M 3.0M 23.12
Kymera Therapeutics (KYMR) 0.4 $66M 4.8M 13.90
Immatics SHS (IMTX) 0.4 $65M 5.6M 11.58
Mirati Therapeutics 0.4 $61M 1.4M 43.56
Kiniksa Pharmaceuticals Com Cl A (KNSA) 0.3 $49M 2.8M 17.37
Ultragenyx Pharmaceutical (RARE) 0.3 $49M 1.4M 35.65
Denali Therapeutics (DNLI) 0.3 $47M 2.3M 20.63
Prelude Therapeutics (PRLD) 0.2 $31M 10M 3.09
Kodiak Sciences (KOD) 0.2 $31M 17M 1.80
Nurix Therapeutics (NRIX) 0.2 $31M 3.9M 7.86
Biomea Fusion (BMEA) 0.2 $29M 2.1M 13.76
Ideaya Biosciences (IDYA) 0.2 $29M 1.1M 26.98
Cerus Corporation (CERS) 0.2 $28M 17M 1.62
Aerovate Therapeutics (AVTE) 0.2 $27M 2.0M 13.57
Igm Biosciences (IGMS) 0.2 $26M 3.2M 8.35
Xenon Pharmaceuticals (XENE) 0.1 $26M 752k 34.16
Cabaletta Bio (CABA) 0.1 $24M 1.6M 15.22
Monte Rosa Therapeutics (GLUE) 0.1 $24M 4.9M 4.79
DBV Technologies Sponsored Adr (DBVT) 0.1 $20M 15M 1.36
Krystal Biotech (KRYS) 0.1 $20M 170k 116.00
Verve Therapeutics (VERV) 0.1 $19M 1.4M 13.26
Bicycle Therapeutics Sponsored Ads (BCYC) 0.1 $17M 844k 20.09
Immunovant (IMVT) 0.1 $16M 425k 38.39
Cogent Biosciences (COGT) 0.1 $13M 1.3M 9.75
Day One Biopharmaceuticals I (DAWN) 0.1 $12M 1.0M 12.27
Prime Medicine (PRME) 0.1 $9.8M 1.0M 9.54
2seventy Bio (TSVT) 0.1 $9.8M 2.5M 3.92
Relay Therapeutics (RLAY) 0.1 $9.8M 1.2M 8.41
Pacific Biosciences of California (PACB) 0.1 $9.4M 1.1M 8.35
Insmed Incorporated Com Par $.01 (INSM) 0.0 $8.7M 343k 25.25
Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.0 $8.6M 11M 0.78
Tango Therapeutics (TNGX) 0.0 $8.4M 750k 11.26
Heron Therapeutics (HRTX) 0.0 $8.4M 8.1M 1.03
Arvinas Ord (ARVN) 0.0 $8.1M 414k 19.64
Taysha Gene Therapies Com Shs (TSHA) 0.0 $7.9M 2.5M 3.16
Sana Biotechnology (SANA) 0.0 $7.7M 2.0M 3.87
Bluebird Bio (BLUE) 0.0 $7.6M 2.5M 3.04
Silverback Therapeutics (SPRY) 0.0 $7.6M 2.0M 3.78
Sagimet Biosciences Inc-a (SGMT) 0.0 $7.2M 815k 8.80
Tscan Therapeutics (TCRX) 0.0 $7.1M 2.8M 2.56
Geron Corporation (GERN) 0.0 $6.5M 3.1M 2.12
Athira Pharma (ATHA) 0.0 $6.4M 3.2M 2.02
Alector (ALEC) 0.0 $6.3M 965k 6.48
Invitae Corporation Series A 4.5% 3/15/2028 (Principal) 0.0 $6.2M 9.3M 0.67
Mirum Pharmaceuticals (MIRM) 0.0 $6.0M 191k 31.60
Edgewise Therapeutics (EWTX) 0.0 $6.0M 1.0M 5.73
Summit Therapeutics (SMMT) 0.0 $5.9M 3.1M 1.87
Stoke Therapeutics (STOK) 0.0 $5.9M 1.5M 3.94
Hookipa Pharma Inc equity (HOOK) 0.0 $5.0M 8.1M 0.62
Morphic Hldg (MORF) 0.0 $4.9M 216k 22.91
Celcuity (CELC) 0.0 $4.9M 536k 9.14
Neoleukin Therapeutics 0.0 $4.8M 1.2M 3.95
Aadi Bioscience (AADI) 0.0 $4.8M 990k 4.84
Opthea Sponsored Ads (OPT) 0.0 $4.7M 2.7M 1.74
Natera (NTRA) 0.0 $4.4M 100k 44.25
Design Therapeutics (DSGN) 0.0 $3.5M 1.5M 2.36
Praxis Precision Medicines I 0.0 $3.2M 1.9M 1.71
Compass Therapeutics (CMPX) 0.0 $3.1M 1.6M 1.97
Talis Biomedical Corporation (TLIS) 0.0 $2.9M 508k 5.77
Gracell Biotechnologies Sponsored Ads 0.0 $2.9M 1.0M 2.88
Sera Prognostics Class A Com (SERA) 0.0 $2.8M 1.5M 1.86
Vaxcyte (PCVX) 0.0 $2.5M 49k 50.98
Xencor (XNCR) 0.0 $2.5M 123k 20.15
Kala Pharmaceuticals (KALA) 0.0 $2.4M 267k 8.90
Achilles Therapeutics Sponsored Ads (ACHL) 0.0 $2.3M 2.6M 0.91
Century Therapeutics (IPSC) 0.0 $2.3M 1.1M 2.00
Affimed Therapeutics B V 0.0 $2.1M 4.4M 0.48
IsoRay (CATX) 0.0 $2.1M 7.6M 0.27
Instil Bio 0.0 $2.0M 4.7M 0.43
Pmv Pharmaceuticals (PMVP) 0.0 $2.0M 322k 6.14
Anaptysbio Inc Common (ANAB) 0.0 $1.9M 106k 17.96
Point Biopharma Global 0.0 $1.7M 250k 6.67
Iteos Therapeutics (ITOS) 0.0 $1.6M 150k 10.95
Leap Therapeutics (LPTX) 0.0 $1.6M 1.2M 1.38
Aligos Therapeutics (ALGS) 0.0 $1.6M 2.1M 0.75
Mersana Therapeutics (MRSN) 0.0 $1.4M 1.1M 1.27
Vor Biopharma (VOR) 0.0 $1.3M 634k 2.12
Invitae (NVTAQ) 0.0 $1.1M 1.8M 0.61
Avidity Biosciences Ord (RNA) 0.0 $1.1M 166k 6.38
Atreca Cl A Com (BCEL) 0.0 $922k 3.5M 0.26
Genetron Holdings Ads 0.0 $370k 455k 0.81
Protara Therapeutics Com Stk (TARA) 0.0 $334k 200k 1.67
Foghorn Therapeutics (FHTX) 0.0 $225k 45k 5.00
Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $34k 833k 0.04