Baker Bros. Advisors as of Dec. 31, 2016
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 133 positions in its portfolio as reported in the December 2016 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seattle Genetics | 23.6 | $2.4B | 46M | 52.77 | |
| Incyte Corporation (INCY) | 23.1 | $2.4B | 24M | 100.27 | |
| Alexion Pharmaceuticals | 7.8 | $801M | 6.5M | 122.35 | |
| ACADIA Pharmaceuticals (ACAD) | 7.3 | $745M | 26M | 28.84 | |
| Incyte Corp Ltd conv | 5.5 | $560M | 275M | 2.04 | |
| Incyte Corp Incy Cvt 144a 0.37 convert | 5.1 | $518M | 259M | 2.00 | |
| Genomic Health | 4.0 | $405M | 14M | 29.39 | |
| BioMarin Pharmaceutical (BMRN) | 3.9 | $398M | 4.8M | 82.84 | |
| Dbv Technologies S A (DBVT) | 1.9 | $194M | 5.5M | 35.13 | |
| Aquinox Pharmaceuticals | 1.7 | $174M | 11M | 16.51 | |
| Beigene (BGNE) | 1.1 | $112M | 3.7M | 30.36 | |
| Abbvie (ABBV) | 1.0 | $106M | 1.7M | 62.62 | |
| Biomarin Pharmaceutical Inc note 1.875% 4/2 | 0.9 | $91M | 22M | 4.05 | |
| BioCryst Pharmaceuticals (BCRX) | 0.7 | $69M | 11M | 6.33 | |
| Amarin Corporation (AMRN) | 0.7 | $68M | 22M | 3.08 | |
| Bellicum Pharma | 0.7 | $66M | 4.9M | 13.62 | |
| Spark Therapeutics | 0.6 | $66M | 1.3M | 49.90 | |
| Acorda Therapeutics | 0.6 | $62M | 3.3M | 18.80 | |
| Achaogen | 0.6 | $60M | 4.6M | 13.02 | |
| Invitae (NVTAQ) | 0.6 | $58M | 7.3M | 7.94 | |
| Advanced Accelerat spon ads each rep 2 ord | 0.6 | $58M | 2.2M | 26.76 | |
| Cerus Corporation (CERS) | 0.6 | $57M | 13M | 4.35 | |
| Exelixis (EXEL) | 0.4 | $45M | 3.0M | 14.91 | |
| Neurocrine Biosciences (NBIX) | 0.3 | $35M | 895k | 38.70 | |
| Heron Therapeutics (HRTX) | 0.3 | $31M | 2.4M | 13.10 | |
| Versartis | 0.3 | $29M | 1.9M | 14.90 | |
| Progenics Pharmaceuticals | 0.3 | $27M | 3.2M | 8.64 | |
| Foamix Pharmaceuticals | 0.3 | $27M | 2.5M | 11.10 | |
| Acorda Therap note 1.75% 6/15 | 0.3 | $27M | 35M | 0.76 | |
| Merus N V (MRUS) | 0.2 | $25M | 1.2M | 21.11 | |
| Array BioPharma | 0.2 | $23M | 2.6M | 8.79 | |
| Xencor (XNCR) | 0.2 | $23M | 872k | 26.32 | |
| Bluebird Bio (BLUE) | 0.2 | $22M | 351k | 61.70 | |
| Ascendis Pharma A S (ASND) | 0.2 | $21M | 1.0M | 20.24 | |
| Derma Sciences | 0.2 | $20M | 3.8M | 5.20 | |
| Aegerion Pharmaceuticals 2% Du cvbond | 0.2 | $19M | 27M | 0.72 | |
| Galapagos Nv- (GLPG) | 0.2 | $17M | 260k | 64.19 | |
| Idera Pharmaceuticals | 0.1 | $15M | 10M | 1.50 | |
| Avexis | 0.1 | $15M | 315k | 47.73 | |
| Aimmune Therapeutics | 0.1 | $14M | 674k | 20.45 | |
| Intellia Therapeutics (NTLA) | 0.1 | $14M | 1.1M | 13.11 | |
| Halozyme Therapeutics (HALO) | 0.1 | $14M | 1.4M | 9.88 | |
| Biomarin Pharmaceutical Inc note 0.750%10/1 | 0.1 | $14M | 12M | 1.12 | |
| Sangamo Biosciences (SGMO) | 0.1 | $12M | 4.1M | 3.05 | |
| Neuroderm Ltd F | 0.1 | $13M | 572k | 22.20 | |
| Mirati Therapeutics | 0.1 | $11M | 2.3M | 4.75 | |
| Aerie Pharmaceuticals | 0.1 | $11M | 299k | 37.85 | |
| Sage Therapeutics (SAGE) | 0.1 | $11M | 208k | 51.06 | |
| Dermira | 0.1 | $9.9M | 326k | 30.33 | |
| Zogenix | 0.1 | $10M | 839k | 12.15 | |
| Intra Cellular Therapies (ITCI) | 0.1 | $9.2M | 609k | 15.09 | |
| Achillion Pharmaceuticals | 0.1 | $7.7M | 1.9M | 4.13 | |
| Alkermes (ALKS) | 0.1 | $8.4M | 150k | 55.58 | |
| Abeona Therapeutics | 0.1 | $8.2M | 1.7M | 4.85 | |
| Ligand Pharmaceuticals In (LGND) | 0.1 | $7.5M | 73k | 101.61 | |
| Macrogenics (MGNX) | 0.1 | $7.4M | 364k | 20.44 | |
| Contrafect | 0.1 | $7.1M | 4.0M | 1.75 | |
| ImmunoGen | 0.1 | $6.2M | 3.0M | 2.04 | |
| Biogen Idec (BIIB) | 0.1 | $4.7M | 17k | 283.58 | |
| Rigel Pharmaceuticals (RIGL) | 0.1 | $4.8M | 2.0M | 2.38 | |
| Catalyst Pharmaceutical Partners (CPRX) | 0.1 | $5.4M | 5.1M | 1.05 | |
| Insmed (INSM) | 0.1 | $5.3M | 400k | 13.23 | |
| Alcobra | 0.1 | $4.9M | 2.3M | 2.10 | |
| Agios Pharmaceuticals (AGIO) | 0.1 | $5.4M | 129k | 41.73 | |
| Dimension Therapeutics | 0.1 | $5.4M | 1.3M | 4.35 | |
| Inotek Pharmaceuticals 5.75% Cb 08/01/2021-registe bond | 0.1 | $5.2M | 5.0M | 1.03 | |
| Array Biopharma Inc note 3.000% 6/0 | 0.0 | $4.2M | 3.0M | 1.40 | |
| Alder Biopharmaceuticals | 0.0 | $4.5M | 217k | 20.80 | |
| Loxo Oncology | 0.0 | $4.4M | 138k | 32.11 | |
| Aevi Genomic | 0.0 | $4.6M | 881k | 5.18 | |
| D Stemline Therapeutics | 0.0 | $3.6M | 334k | 10.70 | |
| Epizyme | 0.0 | $2.8M | 233k | 12.10 | |
| Ultragenyx Pharmaceutical (RARE) | 0.0 | $3.5M | 50k | 70.32 | |
| Trevena | 0.0 | $2.6M | 450k | 5.88 | |
| Ignyta | 0.0 | $3.0M | 571k | 5.30 | |
| Adamas Pharmaceuticals | 0.0 | $2.9M | 173k | 16.90 | |
| Assembly Biosciences | 0.0 | $3.0M | 250k | 12.15 | |
| Minerva Neurosciences | 0.0 | $3.0M | 259k | 11.75 | |
| Natera (NTRA) | 0.0 | $2.9M | 249k | 11.71 | |
| Akari Therapeutics | 0.0 | $3.5M | 497k | 7.04 | |
| Ionis Pharmaceuticals (IONS) | 0.0 | $2.7M | 57k | 47.83 | |
| Selecta Biosciences (RNAC) | 0.0 | $3.0M | 176k | 17.15 | |
| Sunesis Pharmaceuticals Inc Ne | 0.0 | $2.7M | 742k | 3.62 | |
| Ra Pharmaceuticals | 0.0 | $2.7M | 178k | 15.19 | |
| Osiris Therapeutics | 0.0 | $2.5M | 499k | 4.91 | |
| Enanta Pharmaceuticals (ENTA) | 0.0 | $2.5M | 75k | 33.49 | |
| Karyopharm Therapeutics (KPTI) | 0.0 | $2.0M | 217k | 9.40 | |
| Concert Pharmaceuticals I equity | 0.0 | $1.6M | 153k | 10.29 | |
| Glycomimetics (GLYC) | 0.0 | $2.3M | 381k | 6.10 | |
| Protalix Biotherapeutics Inc note 4.500% 9/1 | 0.0 | $2.3M | 3.4M | 0.67 | |
| Trillium Therapeutics, Inc. Cmn | 0.0 | $2.3M | 414k | 5.65 | |
| Invivo Therapeutics Hldgs | 0.0 | $1.7M | 400k | 4.20 | |
| Corbus Pharmaceuticals Hldgs | 0.0 | $2.2M | 260k | 8.45 | |
| Nabriva Therapeutics | 0.0 | $2.1M | 350k | 5.96 | |
| Aeglea Biotherapeutics | 0.0 | $1.8M | 404k | 4.35 | |
| Spring Bk Pharmaceuticals In | 0.0 | $1.8M | 219k | 7.99 | |
| Syros Pharmaceuticals | 0.0 | $2.5M | 205k | 12.16 | |
| Infinity Pharmaceuticals (INFIQ) | 0.0 | $784k | 580k | 1.35 | |
| Palatin Technologies | 0.0 | $1.0M | 2.1M | 0.50 | |
| Chimerix (CMRX) | 0.0 | $530k | 115k | 4.60 | |
| Acceleron Pharma | 0.0 | $734k | 29k | 25.52 | |
| Five Prime Therapeutics | 0.0 | $964k | 19k | 50.09 | |
| Uniqure Nv (QURE) | 0.0 | $1.3M | 230k | 5.60 | |
| Mediwound Ltd cmn | 0.0 | $1.0M | 226k | 4.58 | |
| Aldeyra Therapeutics (ALDX) | 0.0 | $760k | 142k | 5.35 | |
| Scynexis | 0.0 | $1.5M | 468k | 3.19 | |
| Immune Design | 0.0 | $819k | 149k | 5.50 | |
| Cymabay Therapeutics | 0.0 | $535k | 309k | 1.73 | |
| Tenax Therapeutics | 0.0 | $819k | 420k | 1.95 | |
| Proqr Thrapeutics N V shs euro (PRQR) | 0.0 | $1.0M | 213k | 4.90 | |
| Affimed Therapeutics B V | 0.0 | $720k | 400k | 1.80 | |
| Juno Therapeutics | 0.0 | $1.5M | 80k | 18.85 | |
| Proteon Therapeutics | 0.0 | $740k | 389k | 1.90 | |
| Cellectis S A (CLLS) | 0.0 | $848k | 50k | 16.96 | |
| Seres Therapeutics (MCRB) | 0.0 | $1.2M | 125k | 9.90 | |
| Colucid Pharmaceuticals | 0.0 | $1.1M | 30k | 36.39 | |
| Ritter Pharmaceuticals | 0.0 | $1.1M | 400k | 2.71 | |
| Myokardia | 0.0 | $1.3M | 100k | 12.95 | |
| Madrigal Pharmaceuticals (MDGL) | 0.0 | $861k | 58k | 14.91 | |
| Fulgent Genetics (FLGT) | 0.0 | $1.4M | 125k | 11.57 | |
| Alnylam Pharmaceuticals (ALNY) | 0.0 | $425k | 11k | 37.48 | |
| BioDelivery Sciences International | 0.0 | $368k | 210k | 1.75 | |
| Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) | 0.0 | $82k | 13k | 6.19 | |
| Chemocentryx | 0.0 | $363k | 49k | 7.40 | |
| Foundation Medicine | 0.0 | $370k | 21k | 17.71 | |
| La Jolla Pharmaceuticl Com Par | 0.0 | $241k | 14k | 17.53 | |
| Dynavax Technologies (DVAX) | 0.0 | $296k | 75k | 3.95 | |
| Biotime Inc wts oct 1 18 | 0.0 | $14k | 20k | 0.70 | |
| Aptose Biosciences | 0.0 | $359k | 258k | 1.39 | |
| Adaptimmune Therapeutics (ADAP) | 0.0 | $405k | 100k | 4.05 | |
| Arbutus Biopharma (ABUS) | 0.0 | $442k | 181k | 2.45 | |
| Pronai Therapeutics | 0.0 | $298k | 200k | 1.49 | |
| Windtree Therapeutics | 0.0 | $319k | 255k | 1.25 |
