Hambrecht & Quist Capital Management

Tekla Capital Management as of Dec. 31, 2012

Portfolio Holdings for Tekla Capital Management

Tekla Capital Management holds 61 positions in its portfolio as reported in the December 2012 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Gilead Sciences (GILD) 8.8 $55M 752k 73.45
Regeneron Pharmaceuticals (REGN) 8.5 $53M 311k 171.07
Celgene Corporation 7.3 $46M 583k 78.72
Biogen Idec (BIIB) 5.1 $32M 219k 146.67
Alexion Pharmaceuticals 5.0 $31M 330k 93.81
Mylan 3.4 $22M 781k 27.48
Perrigo Company 3.4 $21M 203k 104.03
Puma Biotechnology (PBYI) 3.3 $21M 1.1M 18.75
Hologic (HOLX) 2.6 $16M 813k 20.03
Vertex Pharmaceuticals Incorporated (VRTX) 2.5 $16M 380k 41.94
Shire 2.5 $16M 168k 92.18
Onyx Pharmaceuticals 2.2 $14M 185k 75.53
Medivation 2.1 $13M 261k 51.16
Akorn 2.0 $13M 936k 13.36
Merck & Co (MRK) 1.9 $12M 297k 40.94
Ariad Pharmaceuticals 1.9 $12M 619k 19.18
Teva Pharmaceutical Industries (TEVA) 1.9 $12M 312k 37.34
Cubist Pharmaceuticals 1.8 $11M 266k 42.06
Neurocrine Biosciences (NBIX) 1.8 $11M 1.5M 7.48
Questcor Pharmaceuticals 1.7 $11M 398k 26.72
Allergan 1.6 $10M 109k 91.73
Aetna 1.5 $9.1M 197k 46.30
Thermo Fisher Scientific (TMO) 1.4 $8.7M 136k 63.78
Endo Pharmaceuticals 1.3 $8.4M 318k 26.27
Covance 1.3 $8.1M 140k 57.77
Watson Pharmaceuticals 1.3 $7.9M 92k 86.00
Verastem 1.2 $7.8M 885k 8.79
Alkermes (ALKS) 1.2 $7.7M 417k 18.52
Impax Laboratories 1.1 $7.1M 345k 20.49
Warner Chilcott Plc - 1.1 $7.1M 586k 12.04
Incyte Corporation (INCY) 1.1 $7.0M 421k 16.61
Alere 1.0 $6.5M 352k 18.50
Illumina (ILMN) 1.0 $6.4M 115k 55.59
Amarin Corporation (AMRN) 1.0 $6.4M 790k 8.09
NPS Pharmaceuticals 0.9 $5.9M 650k 9.10
McKesson Corporation (MCK) 0.9 $5.5M 57k 96.95
Edwards Lifesciences (EW) 0.8 $5.2M 58k 90.17
Baxter International (BAX) 0.8 $5.2M 78k 66.66
IDEXX Laboratories (IDXX) 0.8 $5.2M 56k 92.79
Nektar Therapeutics (NKTR) 0.8 $5.0M 675k 7.41
ImmunoGen 0.8 $5.0M 394k 12.75
UnitedHealth (UNH) 0.7 $4.5M 82k 54.24
Accuray Incorporated (ARAY) 0.7 $4.3M 672k 6.43
Intellipharmaceuticsintl Inc C 0.7 $4.3M 1.7M 2.47
United Therapeutics Corporation (UTHR) 0.6 $3.9M 73k 53.42
Acorda Therapeutics 0.6 $3.6M 145k 24.86
Vivus 0.6 $3.5M 262k 13.42
CVS Caremark Corporation (CVS) 0.6 $3.5M 72k 48.34
Curis 0.5 $3.4M 989k 3.43
Ironwood Pharmaceuticals (IRWD) 0.4 $2.3M 208k 11.09
Dendreon Corporation 0.3 $2.0M 377k 5.28
Keryx Biopharmaceuticals 0.3 $1.9M 737k 2.62
Ceres 0.3 $1.9M 427k 4.54
OncoGenex Pharmaceuticals 0.2 $1.5M 113k 13.12
Celldex Therapeutics 0.1 $939k 140k 6.71
Amgen (AMGN) 0.1 $864k 10k 86.32
Endocyte 0.1 $541k 60k 8.99
Icad (ICAD) 0.1 $362k 76k 4.79
Cornerstone Therapeutics 0.1 $313k 66k 4.73
Amicus Therapeutics (FOLD) 0.0 $186k 69k 2.68
Sanofi Aventis Wi Conval Rt 0.0 $177k 104k 1.71