Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2011

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 46 positions in its portfolio as reported in the September 2011 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
GTx 5.2 $9.2M 2.7M 3.35
Trimeris 5.0 $8.8M 3.5M 2.52
Medivation 4.7 $8.2M 483k 16.98
41 Viropharma 4.7 $8.1M 1.1M 7.41
23 Halozyme Therapeutics 4.6 $8.0M 2.9M 2.73
32 Pharmasset 4.1 $7.2M 4.1M 1.76
Exelixis (EXEL) 4.0 $7.0M 1.3M 5.46
Micromet 4.0 $7.0M 3.5M 1.98
10 Auxilium 3.9 $6.8M 6.5M 1.06
Aegerion Pharmaceuticals 3.5 $6.1M 485k 12.67
43 Ym Biosciences 3.5 $6.0M 8.6M 0.70
ACADIA Pharmaceuticals (ACAD) 3.2 $5.7M 5.2M 1.08
12 Biocryst Pharmaceuticals 3.1 $5.3M 5.6M 0.96
Threshold Pharma 3.0 $5.3M 3.7M 1.44
Onyx Pharmaceuticals 2.9 $5.1M 170k 30.01
D Tranzyme 2.9 $5.0M 1.9M 2.64
26 Incyte 2.8 $4.8M 1.1M 4.33
Chelsea Therapeutics International 2.3 $4.1M 1.1M 3.64
8 Ardea Biosciences 2.2 $3.9M 6.0M 0.65
Alere Inc note 3.000% 5/1 2.2 $3.9M 4.5M 0.87
Anthera Pharmaceuticals 2.2 $3.9M 812k 4.77
ZIOPHARM Oncology 2.1 $3.7M 850k 4.41
18 Dendreon 2.0 $3.5M 2.6M 1.35
Amicus Therapeutics (FOLD) 2.0 $3.5M 902k 3.84
31 Pharmacyclics 1.8 $3.2M 7.0M 0.45
Anacor Pharmaceuticals 1.8 $3.1M 539k 5.70
46 Biomarin Pharmaceuticals Notes 1.875% 4/23/2017 conv bonds 1.8 $3.1M 7.9M 0.39
Idenix Pharmaceuticals 1.6 $2.9M 573k 4.99
21 Genomic Health 1.6 $2.8M 7.9M 0.36
Derma Sciences 1.5 $2.6M 340k 7.79
BioDelivery Sciences International 1.5 $2.6M 2.4M 1.09
36 Seattle Genetics 1.2 $2.2M 2.1M 1.06
Raptor Pharmaceutical 1.2 $2.0M 452k 4.51
2 Adolor 1.1 $1.9M 6.9M 0.28
Salix Pharmaceuticals 0.9 $1.5M 52k 29.61
AVANIR Pharmaceuticals 0.8 $1.4M 500k 2.86
9 Ariad Pharmaceuticals 0.7 $1.2M 1.3M 0.96
Ligand Pharmaceuticals 0.6 $1.0M 73k 13.68
Rigel Pharmaceuticals (RIGL) 0.5 $834k 113k 7.36
14 Biomarin 0.4 $752k 337k 2.23
Xoma 0.4 $701k 400k 1.75
Idera Pharmaceuticals 0.2 $340k 288k 1.18
Cumberland Pharmaceuticals (CPIX) 0.1 $132k 24k 5.59
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $63k 21k 3.00
Aradigm Corporation (ARDM) 0.0 $15k 100k 0.15
VIA Pharmaceuticals (VIAP) 0.0 $2.1k 103k 0.02