Baker Bros. Advisors

Latest statistics and disclosures from Baker Bros. Advisors's latest quarterly 13F-HR filing:

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Positions held by Baker Bros. Advisors, LLC consolidated in one spreadsheet with up to 7 years of data

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Portfolio Holdings for Baker Bros. Advisors

Companies in the Baker Bros. Advisors portfolio as of the September 2020 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seagen 37.0 $9.3B NEW 47M 195.69
BeiGene Sponsored Adr (BGNE) 15.2 $3.8B +12% 13M 286.44
Incyte Corporation (INCY) 11.5 $2.9B 32M 89.74
ACADIA Pharmaceuticals (ACAD) 6.9 $1.7B 42M 41.25
Alexion Pharmaceuticals (ALXN) 4.0 $1.0B 8.8M 114.43
Kodiak Sciences (KOD) 2.9 $731M +6% 12M 59.21
BioMarin Pharmaceutical (BMRN) 2.3 $577M 7.6M 76.08
Ascendis Pharma A/S Sponsored Adr (ASND) 2.2 $546M +4% 3.5M 154.32
Invitae (NVTA) 2.1 $514M 12M 43.35
Myokardia (MYOK) 1.6 $410M -4% 3.0M 136.33
Prelude Therapeutics 1.2 $305M NEW 10M 30.13
argenx SE Sponsored Adr (ARGX) 1.1 $268M 1.0M 262.52
Mirati Therapeutics (MRTX) 0.9 $234M 1.4M 166.05
Igm Biosciences (IGMS) 0.9 $232M 3.1M 73.81

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EXACT Sciences Corporation (EXAS) 0.8 $188M 1.8M 101.95
Madrigal Pharmaceuticals (MDGL) 0.7 $178M 1.5M 118.73
Amarin Corporation Sponsored Adr (AMRN) 0.5 $135M -7% 32M 4.21
Heron Therapeutics (HRTX) 0.4 $89M 6.0M 14.82
Forma Therapeutics Holdings SHS (FMTX) 0.4 $88M -11% 1.8M 49.84
Cerus Corporation (CERS) 0.3 $86M 14M 6.26
Zymeworks (ZYME) 0.3 $80M 1.7M 46.58
Insmed Incorporated Com Par $.01 (INSM) 0.3 $73M -24% 2.3M 32.14
Axsome Therapeutics (AXSM) 0.3 $68M -4% 960k 71.25
Neurocrine Biosciences (NBIX) 0.3 $65M -25% 677k 96.16
Kymera Therapeutics 0.3 $63M NEW 2.0M 32.31
Nurix Therapeutics 0.2 $63M NEW 1.8M 34.91
Allakos (ALLK) 0.2 $57M -5% 699k 81.45
ADC Therapeutics SA SHS (ADCT) 0.2 $56M 1.7M 32.99
Rhythm Pharmaceuticals (RYTM) 0.2 $54M -8% 2.5M 21.67
Horizon Therapeutics Public SHS (HZNP) 0.2 $52M +233% 667k 77.68
Global Blood Therapeutics In (GBT) 0.2 $51M +1858% 920k 55.14
Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.2 $51M -5% 6.3M 7.98
Atreca Cl A Com (BCEL) 0.2 $49M 3.5M 13.97
Chemocentryx (CCXI) 0.2 $49M -4% 900k 54.80
Neoleukin Therapeutics (NLTX) 0.2 $46M +12% 3.8M 12.00
BioCryst Pharmaceuticals (BCRX) 0.2 $44M -7% 13M 3.44
Kiniksa Pharmaceuticals Com Cl A (KNSA) 0.2 $43M 2.8M 15.32
Neurocrine Biosciences Note 2.25% 5/15/2024 (Principal) 0.2 $42M 31M 1.38
Krystal Biotech (KRYS) 0.1 $33M -5% 775k 43.05
Pacific Biosciences of California (PACB) 0.1 $32M NEW 3.3M 9.87
Protagonist Therapeutics (PTGX) 0.1 $31M -16% 1.6M 19.55
Aeglea Biotherapeutics (AGLE) 0.1 $31M 4.4M 7.09
Altimmune (ALT) 0.1 $29M +4% 2.2M 13.20
Apellis Pharmaceuticals (APLS) 0.1 $27M 897k 30.17
Assembly Biosciences (ASMB) 0.1 $25M 1.5M 16.44
DBV Technologies Sponsored Adr (DBVT) 0.1 $25M 15M 1.73
Merus N V (MRUS) 0.1 $25M 2.0M 12.00
Aurinia Pharmaceuticals (AUPH) 0.1 $24M -4% 1.6M 14.73
Cymabay Therapeutics (CBAY) 0.1 $24M +113% 3.3M 7.24
Alkermes SHS (ALKS) 0.1 $23M +9% 1.4M 16.57
Fulgent Genetics (FLGT) 0.1 $22M -4% 546k 40.04
Adaptive Biotechnologies Cor (ADPT) 0.1 $21M -4% 441k 48.63
Novavax (NVAX) 0.1 $20M -22% 187k 108.35
Immunomedics (IMMU) 0.1 $20M -27% 238k 85.03
Albireo Pharma (ALBO) 0.1 $18M +48% 549k 33.37
Frequency Therapeutics (FREQ) 0.1 $18M 950k 19.21
Invitae Corporation Note 2.0% 9/1/2024 (Principal) 0.1 $17M NEW 10M 1.64
Athira Pharma 0.1 $16M NEW 882k 18.46
Xencor (XNCR) 0.1 $16M -4% 410k 38.79
BioMarin Pharmaceutical Note 0.599% 8/1/2024 (Principal) 0.1 $16M 15M 1.04
Bluebird Bio (BLUE) 0.1 $14M -4% 252k 53.95
Harmony Biosciences Hldgs In 0.1 $14M NEW 400k 33.90
GW Pharmaceuticals Ads (GWPH) 0.1 $14M -25% 139k 97.35
Mirum Pharmaceuticals (MIRM) 0.0 $11M -5% 553k 19.27
Immatics SHS 0.0 $11M NEW 1.0M 10.61
Vaxart (VXRT) 0.0 $10M -4% 1.6M 6.65
Idera Pharmaceuticals Com Par (IDRA) 0.0 $9.9M 4.6M 2.14
Urovant Sciences SHS (UROV) 0.0 $9.1M -2% 979k 9.34
Sangamo Biosciences (SGMO) 0.0 $9.0M -5% 950k 9.45
Xenon Pharmaceuticals (XENE) 0.0 $8.4M -4% 760k 11.07
Iveric Bio (ISEE) 0.0 $7.9M -14% 1.4M 5.64
Anaptysbio Inc Common (ANAB) 0.0 $7.2M -5% 487k 14.75
uniQure SHS (QURE) 0.0 $7.2M -15% 194k 36.83
Cabaletta Bio (CABA) 0.0 $6.9M 636k 10.84
Hookipa Pharma Inc equity (HOOK) 0.0 $6.6M 701k 9.47
Syros Pharmaceuticals (SYRS) 0.0 $6.1M 690k 8.84
Karuna Therapeutics Ord (KRTX) 0.0 $6.0M -5% 78k 77.32
Burning Rock Biotech Sponsored Ads (BNR) 0.0 $6.0M -5% 237k 25.08
Autolus Therapeutics Sponsored Ads (AUTL) 0.0 $5.4M -5% 461k 11.64
Reata Pharmaceuticals Cl A (RETA) 0.0 $5.2M -5% 53k 97.42
Replimune Group (REPL) 0.0 $4.8M +3918% 207k 23.02
Crinetics Pharmaceuticals In (CRNX) 0.0 $4.7M -4% 302k 15.67
Inflarx Nv (IFRX) 0.0 $4.3M -4% 1.0M 4.26
Iteos Therapeutics 0.0 $4.1M NEW 168k 24.67
Akero Therapeutics (AKRO) 0.0 $4.1M NEW 132k 30.79
Legend Biotech Corporation Sponsored Ads (LEGN) 0.0 $4.0M -5% 128k 30.87
Denali Therapeutics (DNLI) 0.0 $3.6M -5% 99k 35.84
Passage Bio (PASG) 0.0 $3.4M -5% 261k 13.11
Ovid Therapeutics (OVID) 0.0 $3.4M +28% 591k 5.74
Protara Therapeutics Com Stk (TARA) 0.0 $3.4M 200k 16.83
Chiasma (CHMA) 0.0 $3.2M -21% 742k 4.30
Inozyme Pharma 0.0 $3.1M NEW 119k 26.29
Acceleron Pharma (XLRN) 0.0 $2.9M -5% 26k 112.52
Alector (ALEC) 0.0 $2.8M -5% 266k 10.53
Kezar Life Sciences (KZR) 0.0 $2.8M -4% 575k 4.84
Constellation Pharmceticls I (CNST) 0.0 $2.7M 133k 20.26
Gamida Cell SHS (GMDA) 0.0 $2.6M -5% 633k 4.15
Tcr2 Therapeutics Inc cs (TCRR) 0.0 $2.5M NEW 123k 20.32
Intellia Therapeutics (NTLA) 0.0 $2.4M -4% 122k 19.88
Viking Therapeutics (VKTX) 0.0 $2.4M -4% 404k 5.82
Dicerna Pharmaceuticals (DRNA) 0.0 $2.0M -5% 113k 17.99
Arcus Biosciences Incorporated (RCUS) 0.0 $2.0M -5% 115k 17.14
Ngm Biopharmaceuticals (NGM) 0.0 $1.9M -5% 118k 15.91
Galapagos NV Sponsored Adr (GLPG) 0.0 $1.8M -5% 12k 141.88
Bellicum Pharmaceuticals (BLCM) 0.0 $1.6M 249k 6.57
Molecular Templates (MTEM) 0.0 $1.6M -5% 149k 10.92
Oyster Point Pharma (OYST) 0.0 $1.4M -4% 68k 21.11
Orchard Therapeutics Ads (ORTX) 0.0 $1.4M -15% 343k 4.11
Catalyst Pharmaceutical Partners (CPRX) 0.0 $1.4M -5% 474k 2.97
Genetron Holdings Ads (GTH) 0.0 $1.2M NEW 100k 11.94
Leap Therapeutics (LPTX) 0.0 $1.1M -42% 560k 1.98
Evofem Biosciences (EVFM) 0.0 $1.0M -69% 433k 2.36
Applied Therapeutics (APLT) 0.0 $790k -42% 38k 20.77
Galmed Pharmaceuticals SHS (GLMD) 0.0 $725k -4% 205k 3.53
Infinity Pharmaceuticals (INFI) 0.0 $679k 580k 1.17
Adamas Pharmaceuticals (ADMS) 0.0 $675k -5% 164k 4.12
Affimed Therapeutics B V (AFMD) 0.0 $643k -5% 190k 3.39
Aravive (ARAV) 0.0 $357k -68% 76k 4.71
Genfit SA Ads (GNFT) 0.0 $150k 28k 5.28
Sunesis Pharmaceuticals Com Par 0.0 $66k -90% 53k 1.24

Past Filings by Baker Bros. Advisors

SEC 13F filings are viewable for Baker Bros. Advisors going back to 2010

View all past filings