Baker Bros. Advisors as of Sept. 30, 2023
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 101 positions in its portfolio as reported in the September 2023 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 54.5 | $9.5B | 45M | 212.15 | |
| BeiGene Sponsored Adr (BGNE) | 12.1 | $2.1B | 12M | 179.87 | |
| Incyte Corporation (INCY) | 12.0 | $2.1B | 36M | 57.77 | |
| ACADIA Pharmaceuticals (ACAD) | 5.1 | $893M | 43M | 20.84 | |
| BioMarin Pharmaceutical (BMRN) | 1.9 | $337M | 3.8M | 88.48 | |
| Madrigal Pharmaceuticals (MDGL) | 1.3 | $226M | 1.5M | 146.04 | |
| Rhythm Pharmaceuticals (RYTM) | 0.9 | $154M | 6.7M | 22.93 | |
| Roivant Sciences SHS (ROIV) | 0.8 | $139M | 12M | 11.68 | |
| Immunocore Holdings Ads (IMCR) | 0.8 | $131M | 2.5M | 51.90 | |
| Invitae Corporation Note 1.5% 4/1/2028 (Principal) | 0.8 | $130M | 300M | 0.43 | |
| Akero Therapeutics (AKRO) | 0.7 | $120M | 2.4M | 50.58 | |
| Abcellera Biologics (ABCL) | 0.6 | $96M | 21M | 4.60 | |
| BioCryst Pharmaceuticals (BCRX) | 0.5 | $90M | 13M | 7.08 | |
| Replimune Group (REPL) | 0.5 | $78M | 4.6M | 17.11 | |
| Entrada Therapeutics (TRDA) | 0.4 | $77M | 4.9M | 15.80 | |
| Revolution Medicines (RVMD) | 0.4 | $75M | 2.7M | 27.68 | |
| argenx SE Sponsored Adr (ARGX) | 0.4 | $74M | 151k | 491.63 | |
| Springworks Therapeutics (SWTX) | 0.4 | $69M | 3.0M | 23.12 | |
| Kymera Therapeutics (KYMR) | 0.4 | $66M | 4.8M | 13.90 | |
| Immatics SHS (IMTX) | 0.4 | $65M | 5.6M | 11.58 | |
| Mirati Therapeutics | 0.4 | $61M | 1.4M | 43.56 | |
| Kiniksa Pharmaceuticals Com Cl A | 0.3 | $49M | 2.8M | 17.37 | |
| Ultragenyx Pharmaceutical (RARE) | 0.3 | $49M | 1.4M | 35.65 | |
| Denali Therapeutics (DNLI) | 0.3 | $47M | 2.3M | 20.63 | |
| Prelude Therapeutics (PRLD) | 0.2 | $31M | 10M | 3.09 | |
| Kodiak Sciences (KOD) | 0.2 | $31M | 17M | 1.80 | |
| Nurix Therapeutics (NRIX) | 0.2 | $31M | 3.9M | 7.86 | |
| Biomea Fusion (BMEA) | 0.2 | $29M | 2.1M | 13.76 | |
| Ideaya Biosciences (IDYA) | 0.2 | $29M | 1.1M | 26.98 | |
| Cerus Corporation (CERS) | 0.2 | $28M | 17M | 1.62 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $27M | 2.0M | 13.57 | |
| Igm Biosciences (IGMS) | 0.2 | $26M | 3.2M | 8.35 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $26M | 752k | 34.16 | |
| Cabaletta Bio (CABA) | 0.1 | $24M | 1.6M | 15.22 | |
| Monte Rosa Therapeutics (GLUE) | 0.1 | $24M | 4.9M | 4.79 | |
| DBV Technologies Sponsored Adr | 0.1 | $20M | 15M | 1.36 | |
| Krystal Biotech (KRYS) | 0.1 | $20M | 170k | 116.00 | |
| Verve Therapeutics (VERV) | 0.1 | $19M | 1.4M | 13.26 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.1 | $17M | 844k | 20.09 | |
| Immunovant (IMVT) | 0.1 | $16M | 425k | 38.39 | |
| Cogent Biosciences (COGT) | 0.1 | $13M | 1.3M | 9.75 | |
| Day One Biopharmaceuticals I (DAWN) | 0.1 | $12M | 1.0M | 12.27 | |
| Prime Medicine (PRME) | 0.1 | $9.8M | 1.0M | 9.54 | |
| 2seventy Bio (TSVT) | 0.1 | $9.8M | 2.5M | 3.92 | |
| Relay Therapeutics (RLAY) | 0.1 | $9.8M | 1.2M | 8.41 | |
| Pacific Biosciences of California (PACB) | 0.1 | $9.4M | 1.1M | 8.35 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.0 | $8.7M | 343k | 25.25 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.0 | $8.6M | 11M | 0.78 | |
| Tango Therapeutics (TNGX) | 0.0 | $8.4M | 750k | 11.26 | |
| Heron Therapeutics (HRTX) | 0.0 | $8.4M | 8.1M | 1.03 | |
| Arvinas Ord (ARVN) | 0.0 | $8.1M | 414k | 19.64 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.0 | $7.9M | 2.5M | 3.16 | |
| Sana Biotechnology (SANA) | 0.0 | $7.7M | 2.0M | 3.87 | |
| Bluebird Bio (BLUE) | 0.0 | $7.6M | 2.5M | 3.04 | |
| Silverback Therapeutics (SPRY) | 0.0 | $7.6M | 2.0M | 3.78 | |
| Sagimet Biosciences Inc-a (SGMT) | 0.0 | $7.2M | 815k | 8.80 | |
| Tscan Therapeutics (TCRX) | 0.0 | $7.1M | 2.8M | 2.56 | |
| Geron Corporation (GERN) | 0.0 | $6.5M | 3.1M | 2.12 | |
| Athira Pharma (ATHA) | 0.0 | $6.4M | 3.2M | 2.02 | |
| Alector (ALEC) | 0.0 | $6.3M | 965k | 6.48 | |
| Invitae Corporation Series A 4.5% 3/15/2028 (Principal) | 0.0 | $6.2M | 9.3M | 0.67 | |
| Mirum Pharmaceuticals (MIRM) | 0.0 | $6.0M | 191k | 31.60 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $6.0M | 1.0M | 5.73 | |
| Summit Therapeutics (SMMT) | 0.0 | $5.9M | 3.1M | 1.87 | |
| Stoke Therapeutics (STOK) | 0.0 | $5.9M | 1.5M | 3.94 | |
| Hookipa Pharma Inc equity | 0.0 | $5.0M | 8.1M | 0.62 | |
| Morphic Hldg (MORF) | 0.0 | $4.9M | 216k | 22.91 | |
| Celcuity (CELC) | 0.0 | $4.9M | 536k | 9.14 | |
| Neoleukin Therapeutics | 0.0 | $4.8M | 1.2M | 3.95 | |
| Aadi Bioscience (AADI) | 0.0 | $4.8M | 990k | 4.84 | |
| Opthea Sponsored Ads (OPT) | 0.0 | $4.7M | 2.7M | 1.74 | |
| Natera (NTRA) | 0.0 | $4.4M | 100k | 44.25 | |
| Design Therapeutics (DSGN) | 0.0 | $3.5M | 1.5M | 2.36 | |
| Praxis Precision Medicines I | 0.0 | $3.2M | 1.9M | 1.71 | |
| Compass Therapeutics (CMPX) | 0.0 | $3.1M | 1.6M | 1.97 | |
| Talis Biomedical Corporation (TLIS) | 0.0 | $2.9M | 508k | 5.77 | |
| Gracell Biotechnologies Sponsored Ads | 0.0 | $2.9M | 1.0M | 2.88 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $2.8M | 1.5M | 1.86 | |
| Vaxcyte (PCVX) | 0.0 | $2.5M | 49k | 50.98 | |
| Xencor (XNCR) | 0.0 | $2.5M | 123k | 20.15 | |
| Kala Pharmaceuticals (KALA) | 0.0 | $2.4M | 267k | 8.90 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $2.3M | 2.6M | 0.91 | |
| Century Therapeutics (IPSC) | 0.0 | $2.3M | 1.1M | 2.00 | |
| Affimed Therapeutics B V | 0.0 | $2.1M | 4.4M | 0.48 | |
| IsoRay | 0.0 | $2.1M | 7.6M | 0.27 | |
| Instil Bio | 0.0 | $2.0M | 4.7M | 0.43 | |
| Pmv Pharmaceuticals (PMVP) | 0.0 | $2.0M | 322k | 6.14 | |
| Anaptysbio Inc Common (ANAB) | 0.0 | $1.9M | 106k | 17.96 | |
| Point Biopharma Global | 0.0 | $1.7M | 250k | 6.67 | |
| Iteos Therapeutics (ITOS) | 0.0 | $1.6M | 150k | 10.95 | |
| Leap Therapeutics (LPTX) | 0.0 | $1.6M | 1.2M | 1.38 | |
| Aligos Therapeutics (ALGS) | 0.0 | $1.6M | 2.1M | 0.75 | |
| Mersana Therapeutics (MRSN) | 0.0 | $1.4M | 1.1M | 1.27 | |
| Vor Biopharma (VOR) | 0.0 | $1.3M | 634k | 2.12 | |
| Invitae (NVTAQ) | 0.0 | $1.1M | 1.8M | 0.61 | |
| Avidity Biosciences Ord (RNA) | 0.0 | $1.1M | 166k | 6.38 | |
| Atreca Cl A Com (BCEL) | 0.0 | $922k | 3.5M | 0.26 | |
| Genetron Holdings Ads | 0.0 | $370k | 455k | 0.81 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $334k | 200k | 1.67 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $225k | 45k | 5.00 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $34k | 833k | 0.04 |
