Baker Bros. Advisors as of Dec. 31, 2023
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 84 positions in its portfolio as reported in the December 2023 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Incyte Corporation (INCY) | 25.8 | $2.3B | 36M | 62.79 | |
| BeiGene Sponsored Adr (BGNE) | 21.7 | $1.9B | 11M | 180.36 | |
| ACADIA Pharmaceuticals (ACAD) | 15.3 | $1.3B | 43M | 31.31 | |
| Madrigal Pharmaceuticals (MDGL) | 5.2 | $456M | 2.0M | 231.38 | |
| Rhythm Pharmaceuticals (RYTM) | 3.3 | $294M | 6.4M | 45.97 | |
| Mirati Therapeutics | 2.8 | $242M | 4.1M | 58.75 | |
| Immunocore Holdings Ads (IMCR) | 2.0 | $172M | 2.5M | 68.32 | |
| Kymera Therapeutics (KYMR) | 1.7 | $153M | 6.0M | 25.46 | |
| Revolution Medicines (RVMD) | 1.7 | $148M | 5.1M | 28.68 | |
| Invitae Corporation Notes 1.5% 4/1/2028 (Principal) | 1.5 | $131M | 300M | 0.44 | |
| Abcellera Biologics (ABCL) | 1.5 | $131M | 23M | 5.71 | |
| Roivant Sciences SHS (ROIV) | 1.0 | $85M | 7.6M | 11.23 | |
| Replimune Group (REPL) | 0.9 | $81M | 9.5M | 8.43 | |
| Entrada Therapeutics (TRDA) | 0.8 | $73M | 4.9M | 15.09 | |
| Ultragenyx Pharmaceutical (RARE) | 0.8 | $70M | 1.5M | 47.82 | |
| Cerevel Therapeutics Hldng I (CERE) | 0.8 | $68M | 1.6M | 42.40 | |
| Immatics SHS (IMTX) | 0.7 | $62M | 5.8M | 10.53 | |
| BioCryst Pharmaceuticals (BCRX) | 0.7 | $61M | 10M | 5.99 | |
| argenx SE Sponsored Adr (ARGX) | 0.7 | $58M | 151k | 380.43 | |
| Denali Therapeutics (DNLI) | 0.6 | $56M | 2.6M | 21.46 | |
| Akero Therapeutics (AKRO) | 0.6 | $55M | 2.4M | 23.35 | |
| Kodiak Sciences (KOD) | 0.6 | $53M | 17M | 3.04 | |
| Kiniksa Pharmaceuticals Com Cl A | 0.6 | $49M | 2.8M | 17.54 | |
| Xenon Pharmaceuticals (XENE) | 0.5 | $46M | 994k | 46.06 | |
| Prelude Therapeutics (PRLD) | 0.5 | $43M | 10M | 4.27 | |
| Cerus Corporation (CERS) | 0.5 | $42M | 20M | 2.16 | |
| Nurix Therapeutics (NRIX) | 0.5 | $40M | 3.9M | 10.32 | |
| Aerovate Therapeutics (AVTE) | 0.4 | $38M | 1.7M | 22.63 | |
| Ideaya Biosciences (IDYA) | 0.4 | $38M | 1.1M | 35.58 | |
| Edgewise Therapeutics (EWTX) | 0.4 | $34M | 3.1M | 10.94 | |
| Sera Prognostics Class A Com (SERA) | 0.4 | $33M | 5.4M | 5.98 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.4 | $32M | 1.8M | 18.08 | |
| Igm Biosciences (IGMS) | 0.3 | $31M | 3.7M | 8.31 | |
| Biomea Fusion (BMEA) | 0.3 | $31M | 2.1M | 14.52 | |
| Monte Rosa Therapeutics (GLUE) | 0.3 | $28M | 4.9M | 5.65 | |
| Verve Therapeutics (VERV) | 0.3 | $24M | 1.7M | 13.94 | |
| Krystal Biotech (KRYS) | 0.2 | $21M | 170k | 124.06 | |
| Gracell Biotechnologies Sponsored Ads | 0.2 | $21M | 2.1M | 10.04 | |
| Immunovant (IMVT) | 0.2 | $18M | 425k | 42.13 | |
| Tscan Therapeutics (TCRX) | 0.2 | $16M | 2.8M | 5.83 | |
| Day One Biopharmaceuticals I (DAWN) | 0.2 | $15M | 1.0M | 14.60 | |
| DBV Technologies Sponsored Adr | 0.2 | $14M | 15M | 0.95 | |
| Relay Therapeutics (RLAY) | 0.1 | $13M | 1.2M | 11.01 | |
| Silverback Therapeutics (SPRY) | 0.1 | $11M | 2.0M | 5.48 | |
| Stoke Therapeutics (STOK) | 0.1 | $11M | 2.0M | 5.26 | |
| 2seventy Bio (TSVT) | 0.1 | $11M | 2.5M | 4.27 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.1 | $11M | 343k | 30.99 | |
| Celldex Therapeutics (CLDX) | 0.1 | $9.8M | 248k | 39.66 | |
| Prime Medicine (PRME) | 0.1 | $9.1M | 1.0M | 8.86 | |
| Neurogene (NGNE) | 0.1 | $8.8M | 454k | 19.38 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.1 | $8.7M | 11M | 0.79 | |
| Sana Biotechnology (SANA) | 0.1 | $8.2M | 2.0M | 4.08 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.1 | $7.9M | 1.5M | 5.42 | |
| Celcuity (CELC) | 0.1 | $7.8M | 536k | 14.57 | |
| Athira Pharma (ATHA) | 0.1 | $7.7M | 3.2M | 2.43 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $7.6M | 2.6M | 2.95 | |
| Tango Therapeutics (TNGX) | 0.1 | $7.4M | 750k | 9.90 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.1 | $7.1M | 4.0M | 1.77 | |
| Hookipa Pharma Inc equity | 0.1 | $6.6M | 8.1M | 0.81 | |
| Invitae Corporation Series A Notes 4.5% 3/15/2028 (Principal) | 0.1 | $6.3M | 9.3M | 0.68 | |
| Mirum Pharmaceuticals (MIRM) | 0.1 | $5.6M | 191k | 29.52 | |
| Xencor (XNCR) | 0.1 | $5.2M | 245k | 21.23 | |
| Leap Therapeutics (LPTX) | 0.1 | $4.9M | 1.2M | 4.14 | |
| Design Therapeutics (DSGN) | 0.0 | $4.0M | 1.5M | 2.65 | |
| Talis Biomedical Corporation (TLIS) | 0.0 | $3.8M | 508k | 7.45 | |
| IsoRay | 0.0 | $3.1M | 7.6M | 0.40 | |
| Vaxcyte (PCVX) | 0.0 | $3.1M | 49k | 62.80 | |
| Praxis Precision Medicines I | 0.0 | $2.9M | 132k | 22.28 | |
| Century Therapeutics (IPSC) | 0.0 | $2.6M | 798k | 3.32 | |
| Mersana Therapeutics (MRSN) | 0.0 | $2.5M | 1.1M | 2.32 | |
| Compass Therapeutics (CMPX) | 0.0 | $2.4M | 1.6M | 1.56 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $1.9M | 2.1M | 0.89 | |
| Kala Pharmaceuticals (KALA) | 0.0 | $1.9M | 267k | 7.00 | |
| Aligos Therapeutics (ALGS) | 0.0 | $1.4M | 2.1M | 0.66 | |
| Invitae (NVTAQ) | 0.0 | $1.1M | 1.8M | 0.63 | |
| Pfizer (PFE) | 0.0 | $1.0M | 35k | 28.79 | |
| Pmv Pharmaceuticals (PMVP) | 0.0 | $998k | 322k | 3.10 | |
| Aadi Bioscience (AADI) | 0.0 | $509k | 252k | 2.02 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $374k | 200k | 1.88 | |
| Cabaletta Bio (CABA) | 0.0 | $303k | 13k | 22.70 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $290k | 45k | 6.45 | |
| Atreca Cl A Com (BCEL) | 0.0 | $287k | 2.2M | 0.13 | |
| Tyra Biosciences (TYRA) | 0.0 | $147k | 11k | 13.85 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $16k | 833k | 0.02 |
