Baker Bros. Advisors as of March 31, 2025
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 89 positions in its portfolio as reported in the March 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| BeiGene Sponsored Adr (ONC) | 26.5 | $2.4B | 8.8M | 272.17 | |
| Incyte Corporation (INCY) | 20.6 | $1.9B | 31M | 60.55 | |
| ACADIA Pharmaceuticals (ACAD) | 7.9 | $712M | 43M | 16.61 | |
| Madrigal Pharmaceuticals (MDGL) | 7.2 | $654M | 2.0M | 331.23 | |
| Summit Therapeutics (SMMT) | 5.2 | $471M | 24M | 19.29 | |
| Insmed Incorporated Com Par $.01 (INSM) | 4.5 | $411M | 5.4M | 76.29 | |
| Rhythm Pharmaceuticals (RYTM) | 3.3 | $297M | 5.6M | 52.97 | |
| Revolution Medicines (RVMD) | 3.1 | $281M | 7.9M | 35.36 | |
| Kymera Therapeutics (KYMR) | 1.8 | $164M | 6.0M | 27.37 | |
| Alkermes SHS (ALKS) | 1.6 | $148M | 4.5M | 33.02 | |
| Edgewise Therapeutics (EWTX) | 1.5 | $135M | 6.2M | 22.00 | |
| Replimune Group (REPL) | 1.2 | $108M | 11M | 9.75 | |
| Insmed Incorporated Note 0.75% 6/1/2028 (Principal) | 1.1 | $102M | 43M | 2.37 | |
| Immunovant (IMVT) | 1.0 | $93M | 5.5M | 17.09 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 1.0 | $92M | 11M | 8.49 | |
| Immunocore Holdings Ads (IMCR) | 0.8 | $69M | 2.3M | 29.67 | |
| Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) | 0.7 | $63M | 2.8M | 22.21 | |
| Abcellera Biologics (ABCL) | 0.7 | $61M | 28M | 2.23 | |
| Ultragenyx Pharmaceutical (RARE) | 0.6 | $57M | 1.6M | 36.21 | |
| Denali Therapeutics (DNLI) | 0.6 | $51M | 3.7M | 13.60 | |
| Kodiak Sciences (KOD) | 0.5 | $49M | 17M | 2.81 | |
| Nurix Therapeutics (NRIX) | 0.5 | $46M | 3.9M | 11.88 | |
| argenx SE Sponsored Adr (ARGX) | 0.5 | $46M | 78k | 591.87 | |
| Entrada Therapeutics (TRDA) | 0.5 | $44M | 4.9M | 9.04 | |
| Celcuity (CELC) | 0.5 | $43M | 4.3M | 10.11 | |
| Grail (GRAL) | 0.5 | $42M | 1.6M | 25.54 | |
| Roivant Sciences SHS (ROIV) | 0.4 | $38M | 3.8M | 10.09 | |
| Immatics SHS (IMTX) | 0.4 | $33M | 7.3M | 4.51 | |
| Stoke Therapeutics (STOK) | 0.3 | $31M | 4.6M | 6.65 | |
| Cerus Corporation (CERS) | 0.3 | $27M | 19M | 1.39 | |
| Vaxcyte (PCVX) | 0.3 | $24M | 641k | 37.76 | |
| Monte Rosa Therapeutics (GLUE) | 0.3 | $23M | 4.9M | 4.64 | |
| CRISPR Therapeutics Namen Akt (CRSP) | 0.2 | $22M | 654k | 34.03 | |
| Akero Therapeutics (AKRO) | 0.2 | $22M | 549k | 40.48 | |
| Sera Prognostics Class A Com (SERA) | 0.2 | $20M | 5.5M | 3.68 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.2 | $18M | 1.2M | 14.38 | |
| Neurogene (NGNE) | 0.2 | $17M | 1.5M | 11.71 | |
| Ideaya Biosciences (IDYA) | 0.2 | $17M | 1.1M | 16.38 | |
| Verona Pharma Sponsored Ads (VRNA) | 0.2 | $14M | 224k | 63.49 | |
| Candel Therapeutics (CADL) | 0.2 | $14M | 2.4M | 5.65 | |
| Praxis Precision Medicines I (PRAX) | 0.1 | $13M | 332k | 37.87 | |
| 2seventy bio Common Stock | 0.1 | $12M | 2.5M | 4.94 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $12M | 347k | 33.55 | |
| Bicara Therapeutics (BCAX) | 0.1 | $11M | 833k | 13.03 | |
| Ionis Pharmaceuticals (IONS) | 0.1 | $11M | 358k | 30.17 | |
| DBV Technologies Sponsored Ads (DBVT) | 0.1 | $10M | 1.5M | 6.82 | |
| Alumis (ALMS) | 0.1 | $9.6M | 1.6M | 6.14 | |
| Merus N V (MRUS) | 0.1 | $9.4M | 224k | 42.09 | |
| Prelude Therapeutics (PRLD) | 0.1 | $7.8M | 10M | 0.77 | |
| Verve Therapeutics (VERV) | 0.1 | $7.7M | 1.7M | 4.57 | |
| Rocket Pharmaceuticals (RCKT) | 0.1 | $7.3M | 1.1M | 6.67 | |
| Xencor (XNCR) | 0.1 | $7.1M | 670k | 10.64 | |
| Dyne Therapeutics (DYN) | 0.1 | $7.0M | 672k | 10.46 | |
| Kala Pharmaceuticals (KALA) | 0.1 | $6.9M | 1.2M | 5.73 | |
| Design Therapeutics (DSGN) | 0.1 | $6.7M | 1.7M | 3.86 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.1 | $6.3M | 362k | 17.31 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.1 | $5.6M | 4.0M | 1.39 | |
| Regulus Therapeutics | 0.1 | $4.7M | 2.7M | 1.75 | |
| Igm Biosciences (IGMS) | 0.1 | $4.7M | 4.1M | 1.15 | |
| Intellia Therapeutics (NTLA) | 0.1 | $4.6M | 644k | 7.11 | |
| Celldex Therapeutics (CLDX) | 0.0 | $4.5M | 248k | 18.15 | |
| Sionna Therapeutics (SION) | 0.0 | $4.2M | 400k | 10.46 | |
| BioNTech SE Sponsored Ads (BNTX) | 0.0 | $4.1M | 45k | 91.06 | |
| Tscan Therapeutics (TCRX) | 0.0 | $3.8M | 2.8M | 1.38 | |
| Disc Medicine (IRON) | 0.0 | $3.8M | 77k | 49.64 | |
| Vir Biotechnology (VIR) | 0.0 | $3.5M | 543k | 6.48 | |
| Sana Biotechnology (SANA) | 0.0 | $3.4M | 2.0M | 1.68 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.0 | $3.1M | 953k | 3.26 | |
| Relay Therapeutics (RLAY) | 0.0 | $3.0M | 1.2M | 2.62 | |
| Wave Life Sciences SHS (WVE) | 0.0 | $2.8M | 344k | 8.08 | |
| Fate Therapeutics (FATE) | 0.0 | $2.6M | 3.3M | 0.79 | |
| Skye Bioscience (SKYE) | 0.0 | $2.3M | 1.5M | 1.59 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $2.3M | 537k | 4.26 | |
| Enliven Therapeutics (ELVN) | 0.0 | $2.3M | 115k | 19.68 | |
| Contineum Therapeutics Cl A (CTNM) | 0.0 | $2.2M | 313k | 6.98 | |
| Prime Medicine (PRME) | 0.0 | $2.0M | 1.0M | 1.99 | |
| Tectonic Therapeutic (TECX) | 0.0 | $1.8M | 100k | 17.71 | |
| vTv Therapeutics Cl A (VTVT) | 0.0 | $1.7M | 97k | 17.32 | |
| Compass Therapeutics (CMPX) | 0.0 | $1.0M | 548k | 1.90 | |
| Neumora Therapeutics (NMRA) | 0.0 | $1.0M | 1.0M | 1.00 | |
| Hookipa Pharma (HOOK) | 0.0 | $878k | 813k | 1.08 | |
| Generation Bio | 0.0 | $788k | 1.9M | 0.41 | |
| Aligos Therapeutics (ALGS) | 0.0 | $685k | 83k | 8.25 | |
| Leap Therapeutics (CYPH) | 0.0 | $124k | 405k | 0.31 | |
| Century Therapeutics (IPSC) | 0.0 | $115k | 242k | 0.48 | |
| Tyra Biosciences (TYRA) | 0.0 | $99k | 11k | 9.30 | |
| Acrivon Therapeutics Common Stock (ACRV) | 0.0 | $46k | 23k | 2.03 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $25k | 833k | 0.03 | |
| Opthea Sponsored Ads (OPTEY) | 0.0 | $0 | 2.1M | 0.00 |
