Baker Bros. Advisors

Baker Bros. Advisors as of June 30, 2024

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 95 positions in its portfolio as reported in the June 2024 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Incyte Corporation (INCY) 23.8 $1.9B 31M 60.62
BeiGene Sponsored Adr 19.3 $1.5B 11M 142.67
ACADIA Pharmaceuticals (ACAD) 8.9 $697M 43M 16.25
Madrigal Pharmaceuticals (MDGL) 7.1 $553M 2.0M 280.16
Revolution Medicines (RVMD) 3.8 $294M 7.6M 38.81
Rhythm Pharmaceuticals (RYTM) 3.4 $263M 6.4M 41.06
Insmed Incorporated Com Par $.01 (INSM) 3.1 $240M 3.6M 67.00
Bicycle Therapeutics Sponsored Ads (BCYC) 2.4 $190M 9.4M 20.24
Summit Therapeutics (SMMT) 2.3 $181M 23M 7.80
Kymera Therapeutics (KYMR) 2.3 $179M 6.0M 29.85
Edgewise Therapeutics (EWTX) 1.3 $105M 5.8M 18.01
Alkermes SHS (ALKS) 1.3 $101M 4.2M 24.10
Insmed Incorporated Note 0.75% 6/1/2028 (Principal) 1.2 $90M 43M 2.11
Replimune Group (REPL) 1.2 $90M 10M 9.00
Denali Therapeutics (DNLI) 1.1 $87M 3.7M 23.22
Abcellera Biologics (ABCL) 1.0 $82M 28M 2.96
Nurix Therapeutics (NRIX) 1.0 $81M 3.9M 20.87
Immatics SHS (IMTX) 1.0 $75M 6.4M 11.62
Entrada Therapeutics (TRDA) 0.9 $69M 4.9M 14.25
Ultragenyx Pharmaceutical (RARE) 0.8 $60M 1.5M 41.10
Stoke Therapeutics (STOK) 0.8 $59M 4.4M 13.51
Insmed Incorporated Note 1.75% 1/15/2025 (Principal) 0.7 $56M 33M 1.71
Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) 0.7 $53M 2.8M 18.67
Immunocore Holdings Ads (IMCR) 0.7 $51M 1.5M 33.89
argenx SE Sponsored Adr (ARGX) 0.6 $48M 112k 430.04
Kodiak Sciences (KOD) 0.5 $41M 17M 2.35
Xenon Pharmaceuticals (XENE) 0.5 $39M 994k 38.99
Prelude Therapeutics (PRLD) 0.5 $39M 10M 3.81
Ideaya Biosciences (IDYA) 0.5 $37M 1.1M 35.11
Cerus Corporation (CERS) 0.4 $34M 20M 1.76
Sera Prognostics Class A Com (SERA) 0.4 $32M 5.4M 5.92
Krystal Biotech (KRYS) 0.4 $31M 170k 183.64
Celcuity (CELC) 0.4 $31M 1.9M 16.38
Roivant Sciences SHS (ROIV) 0.4 $30M 2.8M 10.57
Igm Biosciences (IGMS) 0.4 $28M 4.1M 6.87
Cerevel Therapeutics Hldng I (CERE) 0.4 $28M 684k 40.89
Akero Therapeutics (AKRO) 0.3 $26M 1.1M 23.46
Dyne Therapeutics (DYN) 0.3 $24M 672k 35.29
Alumis (ALMS) 0.3 $21M 1.6M 13.30
Monte Rosa Therapeutics (GLUE) 0.2 $18M 4.9M 3.74
Merus N V (MRUS) 0.2 $18M 300k 59.17
Neurogene (NGNE) 0.2 $17M 456k 36.39
Tscan Therapeutics (TCRX) 0.2 $16M 2.8M 5.85
Sana Biotechnology (SANA) 0.2 $13M 2.4M 5.46
Immunovant (IMVT) 0.2 $12M 465k 26.40
Xencor (XNCR) 0.1 $10M 545k 18.93
Neumora Therapeutics (NMRA) 0.1 $10M 1.0M 9.83
Fate Therapeutics (FATE) 0.1 $9.8M 3.0M 3.28
2seventy bio Common Stock (TSVT) 0.1 $9.6M 2.5M 3.85
Biomea Fusion (BMEA) 0.1 $9.5M 2.1M 4.50
Celldex Therapeutics (CLDX) 0.1 $9.2M 248k 37.01
Taysha Gene Therapies Com Shs (TSHA) 0.1 $9.0M 4.0M 2.24
Athira Pharma (ATHA) 0.1 $8.4M 3.2M 2.65
Verve Therapeutics (VERV) 0.1 $8.3M 1.7M 4.88
Relay Therapeutics (RLAY) 0.1 $7.6M 1.2M 6.52
Mirum Pharmaceuticals (MIRM) 0.1 $6.5M 191k 34.19
Tango Therapeutics (TNGX) 0.1 $6.4M 750k 8.58
Kala Pharmaceuticals (KALA) 0.1 $6.3M 891k 7.09
DBV Technologies Sponsored Adr (DBVT) 0.1 $5.9M 7.3M 0.80
Design Therapeutics (DSGN) 0.1 $5.7M 1.7M 3.35
Contineum Therapeutics Cl A (CTNM) 0.1 $5.5M 313k 17.61
Praxis Precision Medicines I (PRAX) 0.1 $5.4M 132k 41.36
CRISPR Therapeutics Namen Akt (CRSP) 0.1 $5.4M 100k 54.01
Prime Medicine (PRME) 0.1 $5.3M 1.0M 5.14
Centessa Pharmaceuticals Sponsored Ads (CNTA) 0.1 $5.0M 549k 9.03
Hookipa Pharma (HOOK) 0.1 $4.8M 8.1M 0.59
Sagimet Biosciences Com Ser A (SGMT) 0.1 $4.7M 1.4M 3.42
Crinetics Pharmaceuticals In (CRNX) 0.1 $4.7M 104k 44.79
Talis Biomedical Corporation (TLIS) 0.1 $4.4M 508k 8.66
Alector (ALEC) 0.1 $4.2M 927k 4.54
Opthea Sponsored Ads (OPT) 0.1 $4.2M 2.2M 1.93
Skye Bioscience (SKYE) 0.1 $4.0M 500k 8.01
Vaxcyte (PCVX) 0.0 $3.7M 49k 75.51
Arcturus Therapeutics Hldg I (ARCT) 0.0 $3.7M 151k 24.35
Generation Bio (GBIO) 0.0 $3.4M 1.2M 2.82
Enliven Therapeutics (ELVN) 0.0 $2.7M 115k 23.37
Leap Therapeutics (LPTX) 0.0 $2.3M 1.2M 1.96
Adaptimmune Therapeutics Sponsored Adr (ADAP) 0.0 $2.3M 2.3M 0.97
Mersana Therapeutics (MRSN) 0.0 $2.2M 1.1M 2.01
Century Therapeutics (IPSC) 0.0 $2.0M 798k 2.55
NewAmsterdam Pharma Company Ordinary Shares (NAMS) 0.0 $1.9M 97k 19.21
Sage Therapeutics (SAGE) 0.0 $1.9M 171k 10.86
vTv Therapeutics Cl A (VTVT) 0.0 $1.7M 97k 17.66
Compass Therapeutics (CMPX) 0.0 $1.6M 1.6M 1.00
Protara Therapeutics Com Stk (TARA) 0.0 $1.1M 537k 2.08
Aerovate Therapeutics (AVTE) 0.0 $1.0M 629k 1.66
Pfizer (PFE) 0.0 $979k 35k 27.98
Achilles Therapeutics Sponsored Ads (ACHL) 0.0 $904k 1.1M 0.81
Aligos Therapeutics 0.0 $727k 2.1M 0.35
Pmv Pharmaceuticals (PMVP) 0.0 $522k 322k 1.62
BioCryst Pharmaceuticals (BCRX) 0.0 $468k 76k 6.18
Acrivon Therapeutics Common Stock (ACRV) 0.0 $307k 53k 5.80
Foghorn Therapeutics (FHTX) 0.0 $259k 45k 5.75
Tyra Biosciences (TYRA) 0.0 $170k 11k 15.99
Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $14k 833k 0.02