Baker Bros. Advisors as of June 30, 2025
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 89 positions in its portfolio as reported in the June 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| BeOne Medicines Sponsored Ads (ONC) | 20.7 | $2.1B | 8.8M | 242.07 | |
| Incyte Corporation (INCY) | 20.3 | $2.1B | 31M | 68.10 | |
| ACADIA Pharmaceuticals (ACAD) | 9.0 | $925M | 43M | 21.57 | |
| Insmed Incorporated Com Par $.01 (INSM) | 7.5 | $776M | 7.7M | 100.64 | |
| Summit Therapeutics (SMMT) | 7.0 | $718M | 34M | 21.28 | |
| Madrigal Pharmaceuticals (MDGL) | 5.8 | $598M | 2.0M | 302.64 | |
| Rhythm Pharmaceuticals (RYTM) | 3.4 | $354M | 5.6M | 63.19 | |
| Revolution Medicines (RVMD) | 3.3 | $345M | 9.4M | 36.79 | |
| Kymera Therapeutics (KYMR) | 2.8 | $290M | 6.7M | 43.64 | |
| Alkermes SHS (ALKS) | 1.8 | $183M | 6.4M | 28.61 | |
| Replimune Group (REPL) | 1.0 | $103M | 11M | 9.29 | |
| Ultragenyx Pharmaceutical (RARE) | 1.0 | $101M | 2.8M | 36.36 | |
| Edgewise Therapeutics (EWTX) | 0.9 | $96M | 7.3M | 13.11 | |
| Abcellera Biologics (ABCL) | 0.9 | $94M | 28M | 3.43 | |
| Immunovant (IMVT) | 0.8 | $87M | 5.5M | 16.00 | |
| Grail (GRAL) | 0.8 | $84M | 1.6M | 51.42 | |
| Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) | 0.8 | $78M | 2.8M | 27.67 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.7 | $76M | 11M | 6.95 | |
| Immunocore Holdings Ads (IMCR) | 0.7 | $73M | 2.3M | 31.38 | |
| Celcuity (CELC) | 0.7 | $73M | 5.5M | 13.35 | |
| Kodiak Sciences (KOD) | 0.6 | $65M | 17M | 3.73 | |
| Immatics SHS (IMTX) | 0.5 | $55M | 10M | 5.38 | |
| Stoke Therapeutics (STOK) | 0.5 | $53M | 4.6M | 11.35 | |
| Denali Therapeutics (DNLI) | 0.5 | $52M | 3.7M | 13.99 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.5 | $52M | 2.5M | 20.74 | |
| Ideaya Biosciences (IDYA) | 0.4 | $45M | 2.1M | 21.02 | |
| Nurix Therapeutics (NRIX) | 0.4 | $44M | 3.9M | 11.39 | |
| Roivant Sciences SHS (ROIV) | 0.4 | $43M | 3.8M | 11.27 | |
| BioNTech SE Sponsored Ads (BNTX) | 0.4 | $39M | 369k | 106.47 | |
| Entrada Therapeutics (TRDA) | 0.3 | $33M | 4.9M | 6.72 | |
| Merus N V (MRUS) | 0.3 | $30M | 574k | 52.60 | |
| Praxis Precision Medicines I (PRAX) | 0.3 | $29M | 690k | 42.05 | |
| Intellia Therapeutics (NTLA) | 0.2 | $25M | 2.7M | 9.38 | |
| Miragen Therapeutics (VRDN) | 0.2 | $24M | 1.7M | 13.98 | |
| Monte Rosa Therapeutics (GLUE) | 0.2 | $22M | 4.9M | 4.51 | |
| Verona Pharma Sponsored Ads (VRNA) | 0.2 | $21M | 224k | 94.58 | |
| Vaxcyte (PCVX) | 0.2 | $21M | 641k | 32.51 | |
| argenx SE Sponsored Adr (ARGX) | 0.2 | $21M | 38k | 551.22 | |
| Verve Therapeutics (VERV) | 0.2 | $19M | 1.7M | 11.23 | |
| Cerus Corporation (CERS) | 0.2 | $18M | 13M | 1.41 | |
| Disc Medicine (IRON) | 0.2 | $18M | 337k | 52.96 | |
| Akero Therapeutics (AKRO) | 0.2 | $17M | 325k | 53.36 | |
| Blueprint Medicines (BPMC) | 0.2 | $16M | 126k | 128.18 | |
| Sera Prognostics Class A Com (SERA) | 0.1 | $15M | 5.5M | 2.77 | |
| Arrowhead Pharmaceuticals (ARWR) | 0.1 | $15M | 939k | 15.80 | |
| Neurogene (NGNE) | 0.1 | $15M | 992k | 14.95 | |
| Dianthus Therapeutics (DNTH) | 0.1 | $15M | 790k | 18.63 | |
| Celldex Therapeutics (CLDX) | 0.1 | $14M | 665k | 20.35 | |
| DBV Technologies Sponsored Ads (DBVT) | 0.1 | $13M | 1.5M | 9.16 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $12M | 370k | 31.30 | |
| Cidara Therapeutics (CDTX) | 0.1 | $11M | 227k | 48.71 | |
| Arcellx Common Stock (ACLX) | 0.1 | $11M | 167k | 65.85 | |
| Nuvalent Inc-a (NUVL) | 0.1 | $11M | 144k | 76.30 | |
| Aeglea Biotherapeutics (SYRE) | 0.1 | $9.4M | 627k | 14.97 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.1 | $9.3M | 4.0M | 2.31 | |
| Prelude Therapeutics (PRLD) | 0.1 | $8.2M | 10M | 0.81 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.1 | $8.1M | 280k | 28.76 | |
| Cytomx Therapeutics (CTMX) | 0.1 | $7.9M | 3.5M | 2.27 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.1 | $7.3M | 953k | 7.62 | |
| Sionna Therapeutics (SION) | 0.1 | $6.9M | 400k | 17.35 | |
| Agios Pharmaceuticals (AGIO) | 0.1 | $6.3M | 190k | 33.26 | |
| Rapport Therapeutics (RAPP) | 0.1 | $6.3M | 550k | 11.37 | |
| Skye Bioscience (SKYE) | 0.1 | $6.1M | 1.5M | 4.18 | |
| Design Therapeutics (DSGN) | 0.1 | $5.8M | 1.7M | 3.37 | |
| Kala Pharmaceuticals (KALA) | 0.1 | $5.7M | 1.2M | 4.76 | |
| Sana Biotechnology (SANA) | 0.1 | $5.5M | 2.0M | 2.73 | |
| Xencor (XNCR) | 0.1 | $5.3M | 670k | 7.86 | |
| Alumis (ALMS) | 0.0 | $4.7M | 1.6M | 3.00 | |
| Igm Biosciences (IGMS) | 0.0 | $4.6M | 4.1M | 1.12 | |
| Tscan Therapeutics (TCRX) | 0.0 | $4.0M | 2.8M | 1.45 | |
| Relay Therapeutics (RLAY) | 0.0 | $4.0M | 1.2M | 3.46 | |
| Fate Therapeutics (FATE) | 0.0 | $2.8M | 2.5M | 1.12 | |
| Vir Biotechnology (VIR) | 0.0 | $2.7M | 543k | 5.04 | |
| Enliven Therapeutics (ELVN) | 0.0 | $2.3M | 115k | 20.06 | |
| Wave Life Sciences SHS (WVE) | 0.0 | $2.2M | 344k | 6.50 | |
| Tectonic Therapeutic (TECX) | 0.0 | $2.0M | 100k | 19.87 | |
| Candel Therapeutics (CADL) | 0.0 | $1.8M | 355k | 5.06 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $1.6M | 537k | 3.03 | |
| vTv Therapeutics Cl A (VTVT) | 0.0 | $1.5M | 97k | 15.00 | |
| Rocket Pharmaceuticals (RCKT) | 0.0 | $1.4M | 552k | 2.45 | |
| Contineum Therapeutics Cl A (CTNM) | 0.0 | $1.2M | 313k | 3.97 | |
| Hookipa Pharma (HOOK) | 0.0 | $1.0M | 813k | 1.25 | |
| Neumora Therapeutics (NMRA) | 0.0 | $759k | 1.0M | 0.73 | |
| Generation Bio | 0.0 | $623k | 1.9M | 0.32 | |
| Aligos Therapeutics (ALGS) | 0.0 | $599k | 83k | 7.21 | |
| Tyra Biosciences (TYRA) | 0.0 | $102k | 11k | 9.57 | |
| Acrivon Therapeutics Common Stock (ACRV) | 0.0 | $27k | 23k | 1.19 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $15k | 833k | 0.02 | |
| Opthea Sponsored Ads (OPT) | 0.0 | $0 | 2.1M | 0.00 |
