Baker Bros. Advisors as of March 31, 2023
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 105 positions in its portfolio as reported in the March 2023 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 51.7 | $9.5B | 47M | 202.47 | |
| Incyte Corporation (INCY) | 14.2 | $2.6B | 36M | 72.27 | |
| BeiGene Sponsored Adr (BGNE) | 13.7 | $2.5B | 12M | 215.53 | |
| ACADIA Pharmaceuticals (ACAD) | 4.3 | $789M | 42M | 18.82 | |
| Madrigal Pharmaceuticals (MDGL) | 2.0 | $374M | 1.5M | 242.26 | |
| BioMarin Pharmaceutical (BMRN) | 2.0 | $371M | 3.8M | 97.24 | |
| Immunocore Holdings Ads (IMCR) | 0.7 | $125M | 2.5M | 49.44 | |
| Rhythm Pharmaceuticals (RYTM) | 0.6 | $116M | 6.5M | 17.84 | |
| Kodiak Sciences (KOD) | 0.6 | $107M | 17M | 6.20 | |
| BioCryst Pharmaceuticals (BCRX) | 0.6 | $106M | 13M | 8.34 | |
| argenx SE Sponsored Adr (ARGX) | 0.6 | $104M | 280k | 372.58 | |
| Akero Therapeutics (AKRO) | 0.5 | $91M | 2.4M | 38.26 | |
| Kymera Therapeutics (KYMR) | 0.5 | $85M | 2.9M | 29.63 | |
| Replimune Group (REPL) | 0.4 | $81M | 4.6M | 17.66 | |
| Abcellera Biologics (ABCL) | 0.4 | $79M | 11M | 7.54 | |
| Springworks Therapeutics (SWTX) | 0.4 | $71M | 2.8M | 25.74 | |
| Entrada Therapeutics (TRDA) | 0.4 | $71M | 4.9M | 14.50 | |
| Biomea Fusion (BMEA) | 0.4 | $65M | 2.1M | 31.01 | |
| Revolution Medicines (RVMD) | 0.3 | $58M | 2.7M | 21.66 | |
| Prelude Therapeutics (PRLD) | 0.3 | $58M | 10M | 5.70 | |
| Mirati Therapeutics | 0.3 | $52M | 1.4M | 37.18 | |
| Fibrogen (FGEN) | 0.3 | $49M | 2.6M | 18.66 | |
| Cerus Corporation (CERS) | 0.3 | $48M | 16M | 2.97 | |
| Igm Biosciences (IGMS) | 0.2 | $43M | 3.2M | 13.74 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $40M | 2.0M | 20.17 | |
| Immatics SHS (IMTX) | 0.2 | $36M | 5.2M | 6.90 | |
| Roivant Sciences SHS (ROIV) | 0.2 | $35M | 4.8M | 7.38 | |
| Nurix Therapeutics (NRIX) | 0.2 | $35M | 3.9M | 8.88 | |
| Chinook Therapeutics | 0.2 | $34M | 1.5M | 23.15 | |
| Kiniksa Pharmaceuticals Com Cl A (KNSA) | 0.2 | $30M | 2.8M | 10.76 | |
| Dice Therapeutics | 0.2 | $30M | 1.0M | 28.65 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $27M | 752k | 35.79 | |
| 2seventy Bio (TSVT) | 0.1 | $26M | 2.5M | 10.20 | |
| Denali Therapeutics (DNLI) | 0.1 | $25M | 1.1M | 23.04 | |
| DBV Technologies Sponsored Adr (DBVT) | 0.1 | $25M | 15M | 1.69 | |
| Krystal Biotech (KRYS) | 0.1 | $24M | 303k | 80.06 | |
| Verve Therapeutics (VERV) | 0.1 | $20M | 1.4M | 14.42 | |
| Ultragenyx Pharmaceutical (RARE) | 0.1 | $19M | 471k | 40.10 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.1 | $18M | 844k | 21.27 | |
| Stoke Therapeutics (STOK) | 0.1 | $18M | 2.1M | 8.33 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $17M | 776k | 21.76 | |
| Avidity Biosciences Ord (RNA) | 0.1 | $15M | 1.0M | 15.35 | |
| Blueprint Medicines (BPMC) | 0.1 | $15M | 334k | 44.99 | |
| Silverback Therapeutics (SPRY) | 0.1 | $13M | 2.0M | 6.51 | |
| Pacific Biosciences of California (PACB) | 0.1 | $13M | 1.1M | 11.58 | |
| Prime Medicine (PRME) | 0.1 | $13M | 1.0M | 12.30 | |
| Heron Therapeutics (HRTX) | 0.1 | $12M | 8.1M | 1.51 | |
| Invitae (NVTAQ) | 0.1 | $12M | 8.9M | 1.35 | |
| Ideaya Biosciences (IDYA) | 0.1 | $11M | 833k | 13.73 | |
| Cabaletta Bio (CABA) | 0.1 | $11M | 1.3M | 8.27 | |
| Summit Therapeutics (SMMT) | 0.1 | $11M | 6.3M | 1.75 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.1 | $11M | 9.8M | 1.09 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $11M | 2.7M | 3.95 | |
| Verastem | 0.1 | $11M | 26M | 0.42 | |
| Fate Therapeutics (FATE) | 0.1 | $9.5M | 1.7M | 5.70 | |
| Point Biopharma Global | 0.0 | $8.5M | 1.2M | 7.27 | |
| Bluebird Bio (BLUE) | 0.0 | $7.9M | 2.5M | 3.18 | |
| Allogene Therapeutics (ALLO) | 0.0 | $7.8M | 1.6M | 4.94 | |
| Mersana Therapeutics (MRSN) | 0.0 | $7.8M | 1.9M | 4.11 | |
| Aadi Bioscience (AADI) | 0.0 | $7.2M | 990k | 7.24 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $6.9M | 1.8M | 3.83 | |
| Geron Corporation (GERN) | 0.0 | $6.6M | 3.1M | 2.17 | |
| Sana Biotechnology SHS (SANA) | 0.0 | $6.5M | 2.0M | 3.27 | |
| Aravive | 0.0 | $6.5M | 3.3M | 2.00 | |
| Macrogenics (MGNX) | 0.0 | $6.4M | 893k | 7.17 | |
| Alector (ALEC) | 0.0 | $6.0M | 965k | 6.19 | |
| Athira Pharma (ATHA) | 0.0 | $5.9M | 2.4M | 2.50 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.0 | $5.8M | 343k | 17.05 | |
| Tscan Therapeutics (TCRX) | 0.0 | $5.8M | 2.8M | 2.10 | |
| Natera (NTRA) | 0.0 | $5.6M | 100k | 55.52 | |
| Compass Therapeutics (CMPX) | 0.0 | $5.1M | 1.6M | 3.27 | |
| Affimed Therapeutics B V | 0.0 | $4.9M | 6.6M | 0.75 | |
| Relay Therapeutics (RLAY) | 0.0 | $4.7M | 284k | 16.47 | |
| Atreca Cl A Com (BCEL) | 0.0 | $4.0M | 3.5M | 1.14 | |
| Century Therapeutics (IPSC) | 0.0 | $4.0M | 1.1M | 3.47 | |
| Talis Biomedical Corp | 0.0 | $3.7M | 7.6M | 0.49 | |
| Design Therapeutics (DSGN) | 0.0 | $3.6M | 627k | 5.77 | |
| Instil Bio | 0.0 | $3.5M | 5.3M | 0.66 | |
| Xencor (XNCR) | 0.0 | $3.4M | 123k | 27.89 | |
| Vor Biopharma (VOR) | 0.0 | $3.4M | 634k | 5.38 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $3.3M | 500k | 6.67 | |
| Tango Therapeutics (TNGX) | 0.0 | $3.0M | 750k | 3.95 | |
| Monte Rosa Therapeutics (GLUE) | 0.0 | $2.9M | 375k | 7.79 | |
| Neoleukin Therapeutics | 0.0 | $2.7M | 3.8M | 0.70 | |
| Vera Therapeutics Cl A (VERA) | 0.0 | $2.6M | 333k | 7.76 | |
| Hookipa Pharma Inc equity (HOOK) | 0.0 | $2.6M | 3.5M | 0.74 | |
| Leap Therapeutics | 0.0 | $2.5M | 7.4M | 0.34 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $2.5M | 2.6M | 0.96 | |
| Atara Biotherapeutics (ATRA) | 0.0 | $2.2M | 744k | 2.90 | |
| Iteos Therapeutics (ITOS) | 0.0 | $2.0M | 150k | 13.61 | |
| Female Health (VERU) | 0.0 | $1.9M | 1.6M | 1.16 | |
| Vaxcyte (PCVX) | 0.0 | $1.8M | 49k | 37.48 | |
| Aligos Therapeutics (ALGS) | 0.0 | $1.8M | 2.1M | 0.87 | |
| Pmv Pharmaceuticals (PMVP) | 0.0 | $1.5M | 322k | 4.77 | |
| Praxis Precision Medicines I | 0.0 | $1.5M | 1.9M | 0.81 | |
| Nkarta (NKTX) | 0.0 | $1.4M | 400k | 3.55 | |
| Kala Pharmaceuticals (KALA) | 0.0 | $1.2M | 77k | 15.05 | |
| Tcr2 Therapeutics Inc cs | 0.0 | $1.1M | 753k | 1.50 | |
| Aeglea Biotherapeutics | 0.0 | $989k | 3.4M | 0.29 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $625k | 200k | 3.13 | |
| Genetron Holdings Ads | 0.0 | $478k | 455k | 1.05 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $279k | 45k | 6.20 | |
| Vincera Pharma (VINC) | 0.0 | $251k | 241k | 1.04 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $83k | 833k | 0.10 | |
| Bellicum Pharmaceuticals | 0.0 | $82k | 249k | 0.33 |
