Baker Bros. Advisors as of March 31, 2026
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 84 positions in its portfolio as reported in the March 2026 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Incyte Corporation (INCY) | 16.6 | $2.9B | 31M | 94.12 | |
| BeOne Medicines Sponsored Ads (ONC) | 15.0 | $2.6B | 8.8M | 296.97 | |
| Insmed Incorporated Com Par $.01 (INSM) | 7.0 | $1.2B | 7.4M | 163.52 | |
| Madrigal Pharmaceuticals (MDGL) | 6.4 | $1.1B | 2.1M | 523.47 | |
| ACADIA Pharmaceuticals (ACAD) | 5.5 | $955M | 43M | 22.26 | |
| Revolution Medicines (RVMD) | 5.3 | $929M | 9.6M | 97.25 | |
| Celcuity (CELC) | 5.2 | $904M | 7.9M | 114.14 | |
| Kodiak Sciences (KOD) | 4.4 | $759M | 20M | 38.12 | |
| Kymera Therapeutics (KYMR) | 4.1 | $721M | 8.7M | 83.29 | |
| Summit Therapeutics (SMMT) | 4.0 | $690M | 36M | 18.96 | |
| Praxis Precision Medicines I (PRAX) | 3.2 | $565M | 1.8M | 322.19 | |
| Rhythm Pharmaceuticals (RYTM) | 2.8 | $487M | 5.6M | 86.97 | |
| Alkermes SHS (ALKS) | 2.0 | $354M | 10M | 35.36 | |
| Grail (GRAL) | 1.2 | $208M | 4.0M | 51.68 | |
| Edgewise Therapeutics (EWTX) | 1.2 | $207M | 6.6M | 31.50 | |
| Ionis Pharmaceuticals (IONS) | 0.9 | $154M | 2.0M | 75.09 | |
| Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) | 0.8 | $136M | 2.8M | 48.15 | |
| Immunovant (IMVT) | 0.8 | $136M | 5.5M | 24.84 | |
| Roivant Sciences SHS (ROIV) | 0.8 | $135M | 4.9M | 27.70 | |
| Ideaya Biosciences (IDYA) | 0.8 | $132M | 3.9M | 33.32 | |
| Arrowhead Pharmaceuticals (ARWR) | 0.7 | $125M | 2.0M | 62.70 | |
| Stoke Therapeutics (STOK) | 0.6 | $109M | 3.3M | 32.56 | |
| Immatics SHS (IMTX) | 0.6 | $107M | 11M | 9.84 | |
| Abcellera Biologics (ABCL) | 0.6 | $106M | 30M | 3.49 | |
| Abivax Sponsored Ads (ABVX) | 0.6 | $98M | 876k | 111.35 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.5 | $85M | 2.4M | 36.32 | |
| Replimune Group (REPL) | 0.5 | $85M | 11M | 7.65 | |
| Celcuity Note 2.75% 8/1/2031 | 0.4 | $75M | 31M | 2.43 | |
| Nurix Therapeutics (NRIX) | 0.4 | $72M | 4.7M | 15.50 | |
| Denali Therapeutics (DNLI) | 0.4 | $72M | 3.7M | 19.20 | |
| Dianthus Therapeutics (DNTH) | 0.4 | $72M | 852k | 83.92 | |
| Monte Rosa Therapeutics (GLUE) | 0.4 | $72M | 4.3M | 16.45 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.4 | $69M | 1.4M | 48.20 | |
| Entrada Therapeutics (TRDA) | 0.4 | $64M | 5.1M | 12.62 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.3 | $51M | 11M | 4.64 | |
| Aeglea Biotherapeutics (SYRE) | 0.3 | $50M | 1.0M | 50.44 | |
| Rapport Therapeutics (RAPP) | 0.3 | $48M | 1.5M | 31.29 | |
| Alumis (ALMS) | 0.3 | $44M | 2.0M | 22.03 | |
| Mirum Pharmaceuticals (MIRM) | 0.2 | $41M | 446k | 92.38 | |
| Miragen Therapeutics (VRDN) | 0.2 | $39M | 2.0M | 19.56 | |
| Enliven Therapeutics (ELVN) | 0.2 | $36M | 905k | 39.20 | |
| Prelude Therapeutics (PRLD) | 0.2 | $35M | 10M | 3.42 | |
| DBV Technologies Sponsored Ads (DBVT) | 0.2 | $31M | 1.5M | 20.89 | |
| Design Therapeutics (DSGN) | 0.2 | $28M | 2.6M | 10.64 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 0.2 | $27M | 671k | 39.72 | |
| Cytomx Therapeutics (CTMX) | 0.1 | $23M | 5.0M | 4.70 | |
| Jade Biosciences (JBIO) | 0.1 | $23M | 1.6M | 14.05 | |
| Disc Medicine (IRON) | 0.1 | $22M | 350k | 63.94 | |
| Immunocore Holdings Ads (IMCR) | 0.1 | $22M | 734k | 30.15 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $22M | 370k | 58.15 | |
| Celldex Therapeutics (CLDX) | 0.1 | $21M | 665k | 31.72 | |
| Neurogene (NGNE) | 0.1 | $20M | 992k | 20.16 | |
| Evommune Com Shs (EVMN) | 0.1 | $20M | 847k | 22.99 | |
| Tectonic Therapeutic (TECX) | 0.1 | $19M | 608k | 30.91 | |
| Contineum Therapeutics Cl A (CTNM) | 0.1 | $19M | 1.4M | 13.06 | |
| argenx SE Sponsored Adr (ARGX) | 0.1 | $18M | 25k | 730.25 | |
| Cerus Corporation (CERS) | 0.1 | $18M | 10M | 1.82 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.1 | $18M | 4.0M | 4.47 | |
| Aktis Oncology | 0.1 | $18M | 996k | 17.89 | |
| Generate Biomedicines Com Shs | 0.1 | $18M | 1.4M | 12.50 | |
| Sionna Therapeutics (SION) | 0.1 | $16M | 400k | 40.09 | |
| Dyne Therapeutics (DYN) | 0.1 | $15M | 813k | 18.13 | |
| Xencor (XNCR) | 0.1 | $13M | 1.1M | 12.06 | |
| COMPASS Pathways Sponsored Ads (CMPS) | 0.1 | $13M | 2.3M | 5.53 | |
| Relay Therapeutics (RLAY) | 0.1 | $12M | 1.2M | 9.95 | |
| Sera Prognostics Class A Com (SERA) | 0.1 | $11M | 5.5M | 2.03 | |
| BioNTech SE Sponsored Ads (BNTX) | 0.1 | $11M | 120k | 88.88 | |
| Pharvaris N V (PHVS) | 0.1 | $11M | 375k | 28.25 | |
| Arcus Biosciences Incorporated (RCUS) | 0.1 | $9.0M | 416k | 21.60 | |
| Maplight Therapeutics (MPLT) | 0.0 | $7.4M | 365k | 20.33 | |
| Absci Corp (ABSI) | 0.0 | $6.4M | 2.1M | 3.00 | |
| Wave Life Sciences SHS (WVE) | 0.0 | $6.0M | 823k | 7.25 | |
| vTv Therapeutics Cl A (VTVT) | 0.0 | $5.9M | 148k | 39.66 | |
| Eikon Therapeutics | 0.0 | $5.9M | 556k | 10.58 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $5.1M | 972k | 5.21 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.0 | $5.0M | 953k | 5.22 | |
| LB Pharmaceuticals Com Shs (LBRX) | 0.0 | $4.9M | 200k | 24.66 | |
| Verastem (VSTM) | 0.0 | $3.1M | 585k | 5.30 | |
| Tscan Therapeutics (TCRX) | 0.0 | $2.8M | 2.8M | 1.01 | |
| Skye Bioscience (SKYE) | 0.0 | $968k | 1.6M | 0.61 | |
| Sana Biotechnology (SANA) | 0.0 | $894k | 311k | 2.88 | |
| Aligos Therapeutics (ALGS) | 0.0 | $617k | 83k | 7.43 | |
| Tyra Biosciences (TYRA) | 0.0 | $406k | 11k | 38.30 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $13k | 833k | 0.02 |
