Baker Bros. Advisors as of June 30, 2023
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 107 positions in its portfolio as reported in the June 2023 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 49.6 | $8.6B | 45M | 192.46 | |
| Incyte Corporation (INCY) | 13.0 | $2.3B | 36M | 62.25 | |
| BeiGene Sponsored Adr (BGNE) | 12.0 | $2.1B | 12M | 178.30 | |
| ACADIA Pharmaceuticals (ACAD) | 5.9 | $1.0B | 43M | 23.95 | |
| Madrigal Pharmaceuticals (MDGL) | 2.1 | $357M | 1.5M | 231.00 | |
| BioMarin Pharmaceutical (BMRN) | 1.9 | $330M | 3.8M | 86.68 | |
| Immunocore Holdings Ads (IMCR) | 0.9 | $151M | 2.5M | 59.96 | |
| Invitae Corporation Note 1.5% 4/1/2028 (Principal) | 0.8 | $135M | 300M | 0.45 | |
| Kodiak Sciences (KOD) | 0.7 | $119M | 17M | 6.90 | |
| Akero Therapeutics (AKRO) | 0.6 | $111M | 2.4M | 46.69 | |
| argenx SE Sponsored Adr (ARGX) | 0.6 | $109M | 280k | 389.73 | |
| Rhythm Pharmaceuticals (RYTM) | 0.6 | $107M | 6.5M | 16.49 | |
| Replimune Group (REPL) | 0.6 | $106M | 4.6M | 23.22 | |
| Abcellera Biologics (ABCL) | 0.6 | $106M | 17M | 6.46 | |
| Kymera Therapeutics (KYMR) | 0.6 | $101M | 4.4M | 22.99 | |
| Roivant Sciences SHS (ROIV) | 0.6 | $95M | 9.4M | 10.08 | |
| BioCryst Pharmaceuticals (BCRX) | 0.5 | $90M | 13M | 7.04 | |
| Springworks Therapeutics (SWTX) | 0.5 | $79M | 3.0M | 26.22 | |
| Entrada Therapeutics (TRDA) | 0.4 | $74M | 4.9M | 15.14 | |
| Revolution Medicines (RVMD) | 0.4 | $72M | 2.7M | 26.75 | |
| Immatics SHS (IMTX) | 0.4 | $65M | 5.6M | 11.54 | |
| Chinook Therapeutics | 0.3 | $56M | 1.5M | 38.42 | |
| Mirati Therapeutics | 0.3 | $51M | 1.4M | 36.13 | |
| Dice Therapeutics | 0.3 | $48M | 1.0M | 46.46 | |
| Biomea Fusion (BMEA) | 0.3 | $46M | 2.1M | 21.95 | |
| Prelude Therapeutics (PRLD) | 0.3 | $46M | 10M | 4.50 | |
| Denali Therapeutics (DNLI) | 0.2 | $43M | 1.5M | 29.51 | |
| Kiniksa Pharmaceuticals Com Cl A | 0.2 | $40M | 2.8M | 14.08 | |
| Cerus Corporation (CERS) | 0.2 | $40M | 16M | 2.46 | |
| Nurix Therapeutics (NRIX) | 0.2 | $39M | 3.9M | 9.99 | |
| Ultragenyx Pharmaceutical (RARE) | 0.2 | $36M | 783k | 46.13 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $34M | 2.0M | 17.15 | |
| Igm Biosciences (IGMS) | 0.2 | $29M | 3.2M | 9.23 | |
| Xenon Pharmaceuticals (XENE) | 0.2 | $29M | 752k | 38.50 | |
| ImmunoGen | 0.2 | $29M | 1.5M | 18.87 | |
| DBV Technologies Sponsored Adr | 0.2 | $28M | 15M | 1.90 | |
| Verve Therapeutics (VERV) | 0.2 | $27M | 1.4M | 18.75 | |
| 2seventy bio Common Stock (TSVT) | 0.1 | $25M | 2.5M | 10.12 | |
| Ideaya Biosciences (IDYA) | 0.1 | $25M | 1.1M | 23.50 | |
| Stoke Therapeutics (STOK) | 0.1 | $23M | 2.1M | 10.63 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.1 | $22M | 844k | 25.52 | |
| Monte Rosa Therapeutics (GLUE) | 0.1 | $21M | 3.0M | 6.85 | |
| Cabaletta Bio (CABA) | 0.1 | $21M | 1.6M | 12.91 | |
| Krystal Biotech (KRYS) | 0.1 | $20M | 170k | 117.40 | |
| Summit Therapeutics (SMMT) | 0.1 | $16M | 6.3M | 2.51 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $16M | 776k | 20.34 | |
| Prime Medicine (PRME) | 0.1 | $15M | 1.0M | 14.65 | |
| Pacific Biosciences of California (PACB) | 0.1 | $15M | 1.1M | 13.30 | |
| Relay Therapeutics (RLAY) | 0.1 | $15M | 1.2M | 12.56 | |
| Silverback Therapeutics (SPRY) | 0.1 | $13M | 2.0M | 6.70 | |
| Day One Biopharmaceuticals I (DAWN) | 0.1 | $12M | 1.0M | 11.94 | |
| Sana Biotechnology (SANA) | 0.1 | $12M | 2.0M | 5.96 | |
| Cogent Biosciences (COGT) | 0.1 | $12M | 980k | 11.84 | |
| Point Biopharma Global | 0.1 | $11M | 1.2M | 9.06 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.1 | $10M | 11M | 0.93 | |
| Invitae (NVTAQ) | 0.1 | $10M | 8.9M | 1.13 | |
| Verastem (VSTM) | 0.1 | $9.9M | 1.3M | 7.44 | |
| Geron Corporation (GERN) | 0.1 | $9.8M | 3.1M | 3.21 | |
| Heron Therapeutics (HRTX) | 0.1 | $9.4M | 8.1M | 1.16 | |
| Athira Pharma (ATHA) | 0.1 | $9.3M | 3.2M | 2.95 | |
| Avidity Biosciences Ord (RNA) | 0.1 | $8.9M | 800k | 11.09 | |
| Bluebird Bio (BLUE) | 0.0 | $8.2M | 2.5M | 3.29 | |
| Fate Therapeutics (FATE) | 0.0 | $8.0M | 1.7M | 4.76 | |
| Allogene Therapeutics (ALLO) | 0.0 | $7.8M | 1.6M | 4.97 | |
| Opthea Sponsored Ads (OPT) | 0.0 | $7.5M | 2.7M | 2.80 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.0 | $7.2M | 343k | 21.10 | |
| Tscan Therapeutics (TCRX) | 0.0 | $7.0M | 2.8M | 2.50 | |
| Aadi Bioscience (AADI) | 0.0 | $6.8M | 990k | 6.84 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $5.9M | 1.8M | 3.29 | |
| Alector (ALEC) | 0.0 | $5.8M | 965k | 6.01 | |
| Compass Therapeutics (CMPX) | 0.0 | $5.0M | 1.6M | 3.18 | |
| Natera (NTRA) | 0.0 | $4.9M | 100k | 48.66 | |
| Macrogenics (MGNX) | 0.0 | $4.8M | 893k | 5.35 | |
| Mereo BioPharma Group Sponsored Ads (MREO) | 0.0 | $4.7M | 3.6M | 1.32 | |
| Aravive | 0.0 | $4.1M | 3.3M | 1.26 | |
| Affimed Therapeutics B V | 0.0 | $3.9M | 6.6M | 0.60 | |
| Hookipa Pharma Inc equity | 0.0 | $3.9M | 4.4M | 0.88 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $3.9M | 500k | 7.75 | |
| Gracell Biotechnologies Sponsored Ads | 0.0 | $3.8M | 1.0M | 3.81 | |
| Leap Therapeutics (LPTX) | 0.0 | $3.7M | 1.2M | 3.13 | |
| Talis Biomedical Corporation (TLIS) | 0.0 | $3.7M | 7.6M | 0.48 | |
| Century Therapeutics (IPSC) | 0.0 | $3.6M | 1.1M | 3.16 | |
| Mersana Therapeutics (MRSN) | 0.0 | $3.6M | 1.1M | 3.29 | |
| Atreca Cl A Com (BCEL) | 0.0 | $3.5M | 3.5M | 0.98 | |
| Neoleukin Therapeutics | 0.0 | $3.2M | 3.8M | 0.83 | |
| Design Therapeutics (DSGN) | 0.0 | $3.2M | 500k | 6.30 | |
| Xencor (XNCR) | 0.0 | $3.1M | 123k | 24.97 | |
| Instil Bio | 0.0 | $2.9M | 5.3M | 0.55 | |
| Tango Therapeutics (TNGX) | 0.0 | $2.5M | 750k | 3.32 | |
| Vaxcyte (PCVX) | 0.0 | $2.4M | 49k | 49.94 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $2.4M | 2.6M | 0.95 | |
| Vera Therapeutics Cl A (VERA) | 0.0 | $2.4M | 147k | 16.05 | |
| Praxis Precision Medicines I | 0.0 | $2.2M | 1.9M | 1.15 | |
| Aligos Therapeutics (ALGS) | 0.0 | $2.0M | 2.1M | 0.97 | |
| Pmv Pharmaceuticals (PMVP) | 0.0 | $2.0M | 322k | 6.26 | |
| Iteos Therapeutics (ITOS) | 0.0 | $2.0M | 150k | 13.24 | |
| Vor Biopharma (VOR) | 0.0 | $2.0M | 634k | 3.09 | |
| Kala Pharmaceuticals (KALA) | 0.0 | $1.7M | 116k | 14.59 | |
| IsoRay | 0.0 | $1.5M | 2.3M | 0.67 | |
| Aeglea Biotherapeutics | 0.0 | $1.5M | 3.4M | 0.45 | |
| Fibrogen (FGEN) | 0.0 | $643k | 238k | 2.70 | |
| Nkarta (NKTX) | 0.0 | $594k | 271k | 2.19 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $477k | 200k | 2.39 | |
| Genetron Holdings Ads | 0.0 | $424k | 455k | 0.93 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $317k | 45k | 7.04 | |
| Vincera Pharma (VINC) | 0.0 | $293k | 226k | 1.30 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $46k | 833k | 0.06 |
