Baker Bros. Advisors

Baker Bros. Advisors as of Sept. 30, 2024

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 93 positions in its portfolio as reported in the September 2024 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
BeiGene Sponsored Adr (BGNE) 24.6 $2.4B 11M 224.51
Incyte Corporation (INCY) 21.1 $2.0B 31M 66.10
ACADIA Pharmaceuticals (ACAD) 6.8 $660M 43M 15.38
Summit Therapeutics (SMMT) 5.5 $535M 24M 21.90
Madrigal Pharmaceuticals (MDGL) 4.3 $419M 2.0M 212.22
Revolution Medicines (RVMD) 3.6 $343M 7.6M 45.35
Rhythm Pharmaceuticals (RYTM) 3.5 $335M 6.4M 52.39
Insmed Incorporated Com Par $.01 (INSM) 3.3 $322M 4.4M 73.00
Kymera Therapeutics (KYMR) 2.9 $284M 6.0M 47.33
Bicycle Therapeutics Sponsored Ads (BCYC) 2.2 $213M 9.4M 22.63
Edgewise Therapeutics (EWTX) 1.6 $156M 5.8M 26.69
Replimune Group (REPL) 1.3 $121M 11M 10.96
Alkermes SHS (ALKS) 1.2 $117M 4.2M 27.99
Denali Therapeutics (DNLI) 1.1 $109M 3.7M 29.13
Insmed Incorporated Note 0.75% 6/1/2028 (Principal) 1.0 $98M 43M 2.29
Ultragenyx Pharmaceutical (RARE) 0.9 $88M 1.6M 55.55
Nurix Therapeutics (NRIX) 0.9 $87M 3.9M 22.47
Entrada Therapeutics (TRDA) 0.8 $78M 4.9M 15.98
Immatics SHS (IMTX) 0.8 $74M 6.4M 11.41
Abcellera Biologics (ABCL) 0.7 $72M 28M 2.60
Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) 0.7 $70M 2.8M 24.99
Igm Biosciences (IGMS) 0.7 $68M 4.1M 16.54
argenx SE Sponsored Adr (ARGX) 0.6 $61M 112k 542.08
Stoke Therapeutics (STOK) 0.6 $54M 4.4M 12.29
Immunocore Holdings Ads (IMCR) 0.5 $47M 1.5M 31.13
Kodiak Sciences (KOD) 0.5 $45M 17M 2.61
Sera Prognostics Class A Com (SERA) 0.4 $42M 5.4M 7.80
CRISPR Therapeutics Namen Akt (CRSP) 0.4 $40M 843k 46.98
Xenon Pharmaceuticals (XENE) 0.4 $39M 994k 39.37
Immunovant (IMVT) 0.4 $35M 1.2M 28.51
Cerus Corporation (CERS) 0.4 $34M 20M 1.74
Ideaya Biosciences (IDYA) 0.3 $34M 1.1M 31.68
Roivant Sciences SHS (ROIV) 0.3 $32M 2.8M 11.54
Akero Therapeutics (AKRO) 0.3 $32M 1.1M 28.69
Krystal Biotech (KRYS) 0.3 $31M 170k 182.03
Celcuity (CELC) 0.3 $28M 1.9M 14.91
Monte Rosa Therapeutics (GLUE) 0.3 $26M 4.9M 5.30
Dyne Therapeutics (DYN) 0.3 $24M 672k 35.92
Biomea Fusion (BMEA) 0.2 $21M 2.1M 10.10
Bicara Therapeutics 0.2 $21M 833k 25.47
Prelude Therapeutics (PRLD) 0.2 $21M 10M 2.07
Centessa Pharmaceuticals Sponsored Ads (CNTA) 0.2 $20M 1.2M 15.99
Neurogene (NGNE) 0.2 $19M 456k 41.96
Praxis Precision Medicines I (PRAX) 0.2 $19M 323k 57.54
Alumis (ALMS) 0.2 $17M 1.6M 10.68
Merus N V (MRUS) 0.2 $15M 300k 49.96
Tscan Therapeutics (TCRX) 0.1 $14M 2.8M 4.98
Neumora Therapeutics (NMRA) 0.1 $14M 1.0M 13.21
Xencor (XNCR) 0.1 $14M 670k 20.11
2seventy bio Common Stock (TSVT) 0.1 $12M 2.5M 4.72
Fate Therapeutics (FATE) 0.1 $11M 3.0M 3.50
Arvinas Ord (ARVN) 0.1 $10M 406k 24.63
Sana Biotechnology (SANA) 0.1 $9.9M 2.4M 4.16
Design Therapeutics (DSGN) 0.1 $9.4M 1.7M 5.38
Ionis Pharmaceuticals (IONS) 0.1 $9.0M 224k 40.06
Opthea Sponsored Ads (OPT) 0.1 $8.8M 2.2M 4.07
Celldex Therapeutics (CLDX) 0.1 $8.4M 248k 33.99
Relay Therapeutics (RLAY) 0.1 $8.2M 1.2M 7.08
Verve Therapeutics (VERV) 0.1 $8.2M 1.7M 4.84
Taysha Gene Therapies Com Shs (TSHA) 0.1 $8.0M 4.0M 2.01
Mirum Pharmaceuticals (MIRM) 0.1 $7.4M 191k 39.00
Contineum Therapeutics Cl A (CTNM) 0.1 $6.0M 313k 19.14
Tango Therapeutics (TNGX) 0.1 $5.8M 750k 7.70
Skye Bioscience (SKYE) 0.1 $5.6M 1.4M 3.91
Vaxcyte (PCVX) 0.1 $5.6M 49k 114.27
Crinetics Pharmaceuticals In (CRNX) 0.1 $5.3M 104k 51.10
DBV Technologies Sponsored Adr (DBVT) 0.1 $5.1M 7.3M 0.70
Kala Pharmaceuticals (KALA) 0.1 $5.1M 891k 5.70
Generation Bio (GBIO) 0.0 $4.8M 1.9M 2.47
Alector (ALEC) 0.0 $4.3M 927k 4.66
Prime Medicine (PRME) 0.0 $4.0M 1.0M 3.87
Sagimet Biosciences Com Ser A (SGMT) 0.0 $3.8M 1.4M 2.77
Structure Therapeutics Sponsored Ads (GPCR) 0.0 $3.8M 86k 43.89
Arcturus Therapeutics Hldg I (ARCT) 0.0 $3.5M 151k 23.21
Hookipa Pharma (HOOK) 0.0 $3.5M 813k 4.30
Leap Therapeutics (LPTX) 0.0 $3.0M 1.2M 2.57
Enliven Therapeutics (ELVN) 0.0 $2.9M 115k 25.54
Compass Therapeutics (CMPX) 0.0 $2.9M 1.6M 1.84
Wave Life Sciences SHS (WVE) 0.0 $2.8M 344k 8.20
Mersana Therapeutics (MRSN) 0.0 $2.1M 1.1M 1.89
NewAmsterdam Pharma Company Ordinary Shares (NAMS) 0.0 $1.6M 97k 16.60
Century Therapeutics (IPSC) 0.0 $1.4M 798k 1.71
vTv Therapeutics Cl A (VTVT) 0.0 $1.3M 97k 13.56
Aerovate Therapeutics (AVTE) 0.0 $1.3M 629k 2.09
Pfizer (PFE) 0.0 $1.0M 35k 28.94
Protara Therapeutics Com Stk (TARA) 0.0 $982k 537k 1.83
Aligos Therapeutics 0.0 $719k 83k 8.66
BioCryst Pharmaceuticals (BCRX) 0.0 $576k 76k 7.60
Pmv Pharmaceuticals (PMVP) 0.0 $480k 322k 1.49
Foghorn Therapeutics (FHTX) 0.0 $419k 45k 9.31
Acrivon Therapeutics Common Stock (ACRV) 0.0 $370k 53k 7.00
Tyra Biosciences (TYRA) 0.0 $249k 11k 23.51
Surrozen W Exp 8/11/2026 (SRZNW) 0.0 $8.6k 833k 0.01