Baker Bros. Advisors as of June 30, 2026
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 84 positions in its portfolio as reported in the June 2026 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Incyte Corporation (INCY) | 17.5 | $3.5B | 31M | 113.36 | |
| BeOne Medicines Sponsored Ads (ONC) | 12.6 | $2.5B | 8.8M | 284.97 | |
| Revolution Medicines (RVMD) | 10.7 | $2.1B | 11M | 187.28 | |
| Madrigal Pharmaceuticals (MDGL) | 5.8 | $1.2B | 2.1M | 536.95 | |
| ACADIA Pharmaceuticals (ACAD) | 5.4 | $1.1B | 43M | 25.30 | |
| Kymera Therapeutics (KYMR) | 5.0 | $993M | 8.7M | 114.67 | |
| Insmed Incorporated Com Par $.01 (INSM) | 4.7 | $938M | 8.8M | 106.62 | |
| Celcuity (CELC) | 4.2 | $828M | 7.9M | 104.62 | |
| Kodiak Sciences (KOD) | 3.9 | $776M | 20M | 38.96 | |
| Rhythm Pharmaceuticals (RYTM) | 3.1 | $622M | 5.6M | 111.03 | |
| Praxis Precision Medicines I (PRAX) | 2.9 | $587M | 1.8M | 334.79 | |
| Alkermes SHS (ALKS) | 2.6 | $525M | 10M | 52.40 | |
| Summit Therapeutics (SMMT) | 2.4 | $478M | 33M | 14.57 | |
| Grail (GRAL) | 1.4 | $275M | 4.0M | 68.27 | |
| Abcellera Biologics (ABCL) | 1.3 | $259M | 33M | 7.85 | |
| Immunovant (IMVT) | 1.0 | $209M | 5.4M | 38.53 | |
| Ideaya Biosciences (IDYA) | 0.9 | $187M | 5.0M | 37.27 | |
| Kiniksa Pharmaceuticals International Ord Shs Cl A (KNSA) | 0.9 | $181M | 2.8M | 63.95 | |
| Roivant Sciences SHS (ROIV) | 0.8 | $167M | 4.7M | 35.39 | |
| Arrowhead Pharmaceuticals (ARWR) | 0.8 | $162M | 2.0M | 81.51 | |
| Ionis Pharmaceuticals (IONS) | 0.8 | $162M | 2.0M | 79.29 | |
| Edgewise Therapeutics (EWTX) | 0.8 | $150M | 3.7M | 40.63 | |
| Replimune Group (REPL) | 0.6 | $122M | 11M | 11.07 | |
| Nurix Therapeutics (NRIX) | 0.6 | $113M | 4.7M | 24.26 | |
| Stoke Therapeutics (STOK) | 0.5 | $109M | 3.3M | 32.72 | |
| Monte Rosa Therapeutics (GLUE) | 0.5 | $105M | 4.3M | 24.20 | |
| Immatics SHS (IMTX) | 0.5 | $96M | 9.5M | 10.13 | |
| Denali Therapeutics (DNLI) | 0.5 | $96M | 3.7M | 25.72 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.4 | $88M | 2.4M | 37.42 | |
| Dianthus Therapeutics (DNTH) | 0.4 | $83M | 852k | 97.48 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.4 | $77M | 1.4M | 53.67 | |
| Celcuity Note 2.75% 8/1/2031 (Principal) | 0.3 | $69M | 31M | 2.25 | |
| Rapport Therapeutics (RAPP) | 0.3 | $65M | 1.5M | 41.67 | |
| Alumis (ALMS) | 0.3 | $57M | 2.0M | 28.14 | |
| Prelude Therapeutics (PRLD) | 0.3 | $54M | 10M | 5.33 | |
| Relay Therapeutics (RLAY) | 0.3 | $53M | 2.8M | 18.71 | |
| Mirum Pharmaceuticals (MIRM) | 0.3 | $52M | 446k | 117.07 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.2 | $46M | 11M | 4.24 | |
| Enliven Therapeutics (ELVN) | 0.2 | $46M | 905k | 50.75 | |
| Celldex Therapeutics (CLDX) | 0.2 | $44M | 1.2M | 37.21 | |
| Miragen Therapeutics (VRDN) | 0.2 | $44M | 2.4M | 18.37 | |
| Design Therapeutics (DSGN) | 0.2 | $39M | 2.7M | 14.47 | |
| Entrada Therapeutics (TRDA) | 0.2 | $37M | 5.1M | 7.36 | |
| Sensei Biotherapeutics (FTH) | 0.2 | $32M | 1.3M | 25.00 | |
| Aktis Oncology (AKTS) | 0.2 | $32M | 996k | 32.23 | |
| Neurogene (NGNE) | 0.2 | $31M | 992k | 31.45 | |
| Jade Biosciences (JBIO) | 0.1 | $27M | 1.2M | 22.22 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.1 | $27M | 4.0M | 6.81 | |
| Arcus Biosciences Incorporated (RCUS) | 0.1 | $26M | 845k | 30.83 | |
| Disc Medicine (IRON) | 0.1 | $26M | 350k | 73.14 | |
| Absci Corp (ABSI) | 0.1 | $25M | 2.1M | 11.59 | |
| Generate Biomedicines Com Shs (GENB) | 0.1 | $24M | 1.4M | 16.87 | |
| DBV Technologies Sponsored Ads (DBVT) | 0.1 | $24M | 1.5M | 16.40 | |
| Xenon Pharmaceuticals (XENE) | 0.1 | $22M | 370k | 60.36 | |
| Tectonic Therapeutic (TECX) | 0.1 | $21M | 608k | 34.38 | |
| Cerus Corporation (CERS) | 0.1 | $19M | 6.4M | 2.92 | |
| Cytomx Therapeutics (CTMX) | 0.1 | $19M | 5.0M | 3.75 | |
| Dyne Therapeutics (DYN) | 0.1 | $18M | 813k | 22.21 | |
| Cytokinetics (CYTK) | 0.1 | $18M | 211k | 85.19 | |
| Xencor (XNCR) | 0.1 | $18M | 1.1M | 16.10 | |
| Sionna Therapeutics (SION) | 0.1 | $18M | 400k | 43.99 | |
| Intellia Therapeutics (NTLA) | 0.1 | $16M | 930k | 16.92 | |
| Parabilis Medicines | 0.1 | $14M | 500k | 27.37 | |
| Maplight Therapeutics (MPLT) | 0.1 | $13M | 365k | 35.84 | |
| Avalyn Pharma Com Shs | 0.1 | $12M | 350k | 32.92 | |
| Evommune Com Shs (EVMN) | 0.1 | $11M | 847k | 13.29 | |
| BioNTech SE Sponsored Ads (BNTX) | 0.1 | $11M | 120k | 93.05 | |
| Tango Therapeutics (TNGX) | 0.1 | $10M | 333k | 31.26 | |
| Avalo Therapeutics Ord (AVTX) | 0.1 | $10M | 550k | 18.48 | |
| Sera Prognostics Class A Com (SERA) | 0.1 | $10M | 5.5M | 1.82 | |
| Verastem (VSTM) | 0.0 | $9.5M | 2.5M | 3.82 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.0 | $7.4M | 953k | 7.73 | |
| Eikon Therapeutics (EIKN) | 0.0 | $7.2M | 556k | 13.05 | |
| LB Pharmaceuticals Com Shs (LBRX) | 0.0 | $6.5M | 200k | 32.45 | |
| vTv Therapeutics Cl A (VTVT) | 0.0 | $5.6M | 148k | 37.65 | |
| Wave Life Sciences SHS (WVE) | 0.0 | $4.8M | 823k | 5.81 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $3.7M | 972k | 3.82 | |
| Tscan Therapeutics (TCRX) | 0.0 | $2.7M | 2.8M | 0.98 | |
| Immunome (IMNM) | 0.0 | $1.2M | 55k | 21.19 | |
| Skye Bioscience (SKYE) | 0.0 | $1.1M | 1.6M | 0.69 | |
| Sana Biotechnology (SANA) | 0.0 | $1.1M | 311k | 3.49 | |
| Aligos Therapeutics (ALGS) | 0.0 | $479k | 83k | 5.77 | |
| Tyra Biosciences (TYRA) | 0.0 | $339k | 11k | 31.94 | |
| Surrozen, Inc. Warrants @ $172.50 8/11/2026 W Exp 8/11/2026 (SRZNW) | 0.0 | $14k | 833k | 0.02 |
