Baker Bros. Advisors

Baker Bros. Advisors as of June 30, 2013

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 75 positions in its portfolio as reported in the June 2013 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Pharmacyclics 16.9 $856M 11M 79.47
Seattle Genetics 12.0 $608M 19M 31.46
Genomic Health 8.6 $433M 14M 31.71
Incyte Genomics Notes 4.75% 10/1/2015 conv bonds 8.0 $402M 158M 2.55
Synageva Biopharma 7.7 $387M 9.2M 41.98
ACADIA Pharmaceuticals (ACAD) 7.2 $362M 20M 18.15
Salix Pharmaceuticals Inc note 2.750% 5/1 6.6 $334M 219M 1.52
Incyte Corporation (INCY) 6.4 $326M 15M 22.00
ViroPharma Incorporated 4.8 $244M 8.5M 28.65
Auxilium Pharmaceuticals note 1.7 $88M 92M 0.96
XOMA CORP Common equity shares 1.5 $74M 20M 3.63
Gilead Sciences (GILD) 1.3 $64M 1.2M 51.27
Biomarin Pharmaceutical Inc note 1.875% 4/2 1.2 $63M 23M 2.76
Aegerion Pharmaceuticals 1.2 $59M 924k 63.34
Halozyme Therapeutics (HALO) 1.0 $52M 6.6M 7.95
Repros Therapeutics 1.0 $51M 2.8M 18.45
Medivation Inc note 2.625% 4/0 1.0 $50M 40M 1.27
Gilead Sciences conv 1.0 $49M 22M 2.26
Itmn 2 1/2 12/15/17 0.9 $44M 41M 1.07
BioMarin Pharmaceutical (BMRN) 0.9 $44M 783k 55.74
Cerus Corporation (CERS) 0.7 $37M 8.5M 4.42
Clovis Oncology 0.7 $35M 525k 66.98
Vanda Pharmaceuticals (VNDA) 0.6 $32M 4.0M 8.08
Ariad Pharmaceuticals 0.5 $25M 1.5M 17.49
D Stemline Therapeutics 0.4 $22M 900k 23.84
Intercept Pharmaceuticals In 0.4 $21M 463k 44.84
Medivation 0.4 $20M 398k 49.20
Progenics Pharmaceuticals 0.4 $19M 4.2M 4.46
Derma Sciences 0.4 $18M 1.4M 13.35
Intermune cv 5.0% 0.3 $18M 17M 1.05
Infinity Pharmaceuticals (INFIQ) 0.3 $17M 1.0M 16.19
AVANIR Pharmaceuticals 0.3 $17M 3.6M 4.60
Questcor Pharmaceuticals 0.3 $14M 316k 45.44
Chelsea Therapeutics International 0.2 $11M 4.8M 2.30
Synergy Pharmaceuticals 0.2 $11M 2.6M 4.32
Insmed (INSM) 0.2 $9.5M 796k 11.96
Portola Pharmaceuticals 0.2 $9.8M 400k 24.57
Ironwood Pharmaceuticals (IRWD) 0.2 $9.2M 922k 9.93
BioCryst Pharmaceuticals (BCRX) 0.2 $8.6M 5.6M 1.55
Threshold Pharma 0.2 $8.4M 1.6M 5.26
Synta Pharmaceuticals 0.1 $7.0M 1.4M 4.99
Array BioPharma 0.1 $6.8M 1.5M 4.54
ISIS Pharmaceuticals 0.1 $6.6M 247k 26.87
Qlt 0.1 $6.7M 1.5M 4.39
XenoPort 0.1 $5.1M 1.0M 4.95
Anacor Pharmaceuticals 0.1 $4.9M 877k 5.59
Chemocentryx 0.1 $5.3M 375k 14.14
Ambit Bioscience 0.1 $5.2M 748k 7.00
Prothena (PRTA) 0.1 $4.8M 370k 12.91
Kythera Biopharmaceuticals I 0.1 $4.5M 165k 27.05
BioDelivery Sciences International 0.1 $3.7M 901k 4.06
Achillion Pharmaceuticals 0.1 $3.7M 455k 8.18
Zogenix 0.1 $3.4M 2.0M 1.71
Puma Biotechnology (PBYI) 0.1 $3.7M 83k 44.36
Mei Pharma 0.1 $3.7M 516k 7.13
Salix Pharmaceuticals 0.1 $3.0M 46k 66.16
Idera Pharmaceuticals 0.1 $3.0M 4.5M 0.66
INC Ventrus Biosciences 0.1 $2.9M 1.2M 2.40
Ligand Pharmaceuticals 0.1 $2.7M 73k 37.40
Discovery Laboratories 0.1 $2.3M 1.5M 1.52
ArQule 0.0 $2.0M 880k 2.32
Cytrx 0.0 $2.0M 1.0M 2.00
Enanta Pharmaceuticals (ENTA) 0.0 $2.2M 125k 17.71
Receptos 0.0 $2.0M 100k 19.89
Geron Corporation (GERN) 0.0 $1.5M 1.0M 1.50
OraSure Technologies (OSUR) 0.0 $945k 244k 3.88
Amicus Therapeutics (FOLD) 0.0 $1.2M 515k 2.33
Biodel 0.0 $961k 230k 4.18
Tesaro 0.0 $1.0M 31k 32.74
Lpath 0.0 $880k 200k 4.40
ZIOPHARM Oncology 0.0 $536k 254k 2.11
Epizyme 0.0 $563k 20k 28.15
Cubist Pharmaceuticals 0.0 $241k 5.0k 48.20
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $151k 21k 7.20
Aradigm Corporation (ARDM) 0.0 $16k 100k 0.16