Baker Bros. Advisors

Baker Bros. Advisors as of Dec. 31, 2019

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 99 positions in its portfolio as reported in the December 2019 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Seattle Genetics 30.4 $5.7B 50M 114.26
Incyte Corporation (INCY) 14.8 $2.8B 32M 87.32
Beigene (BGNE) 10.4 $2.0B 12M 165.76
ACADIA Pharmaceuticals (ACAD) 9.3 $1.7B 41M 42.78
Alexion Pharmaceuticals 4.8 $893M 8.3M 108.15
Kodiak Sciences (KOD) 4.2 $795M 11M 71.95
Amarin Corporation (AMRN) 3.9 $740M 35M 21.44
BioMarin Pharmaceutical (BMRN) 3.4 $642M 7.6M 84.55
Ascendis Pharma A S (ASND) 2.5 $472M 3.4M 139.12
EXACT Sciences Corporation (EXAS) 1.3 $239M 2.6M 92.48
Mirati Therapeutics (MRTX) 0.9 $168M 1.3M 128.86
Argenx Se (ARGX) 0.9 $164M 1.0M 160.52
Dbv Technologies S A (DBVT) 0.8 $156M 15M 10.70
Invitae (NVTA) 0.8 $147M 9.1M 16.13
Heron Therapeutics (HRTX) 0.8 $141M 6.0M 23.50
Neurocrine Biosciences (NBIX) 0.7 $135M 1.3M 107.49
Myokardia 0.7 $129M 1.8M 72.88
Igm Biosciences (IGMS) 0.6 $120M 3.1M 38.16
Madrigal Pharmaceuticals (MDGL) 0.6 $107M 1.2M 91.11
Ra Pharmaceuticals 0.5 $98M 2.1M 46.93
Principia Biopharma 0.5 $98M 1.8M 54.78
Axsome Therapeutics (AXSM) 0.5 $86M 830k 103.36
Zymeworks 0.4 $78M 1.7M 45.46
Tricida 0.4 $74M 2.0M 37.74
Rhythm Pharmaceuticals (RYTM) 0.3 $62M 2.7M 22.96
Insmed (INSM) 0.3 $58M 2.4M 23.88
Krystal Biotech (KRYS) 0.3 $57M 1.0M 55.38
Atreca Inc Cl A (BCEL) 0.3 $55M 3.5M 15.47
Audentes Therapeutics 0.3 $48M 805k 59.84
Neurocrine Biosciences Inc Note 2.250 5/1 0.2 $47M 31M 1.53
Cerus Corporation (CERS) 0.2 $45M 11M 4.22
Neoleukin Therapeutics 0.2 $42M 3.4M 12.32
Gw Pharmaceuticals Plc ads 0.2 $39M 371k 104.56
BioCryst Pharmaceuticals (BCRX) 0.2 $38M 11M 3.45
Uniqure Nv (QURE) 0.2 $37M 518k 71.66
Aurinia Pharmaceuticals (AUPH) 0.2 $35M 1.7M 20.26
Adaptive Biotechnologies Cor (ADPT) 0.2 $33M 1.1M 29.92
Assembly Biosciences (ASMB) 0.2 $32M 1.5M 20.46
Allakos (ALLK) 0.2 $32M 340k 95.36
Chemocentryx 0.2 $29M 739k 39.55
Kiniksa Pharmaceuticals (KNSA) 0.2 $31M 2.8M 11.06
Merus N V (MRUS) 0.1 $29M 2.0M 14.08
Urogen Pharma (URGN) 0.1 $28M 832k 33.37
Aimmune Therapeutics 0.1 $23M 674k 33.47
Frequency Therapeutics 0.1 $22M 1.2M 17.53
Alkermes (ALKS) 0.1 $16M 793k 20.40
Xencor (XNCR) 0.1 $15M 428k 34.39
Biomarin Pharma Inc convertible/ 0.1 $16M 15M 1.06
Apellis Pharmaceuticals (APLS) 0.1 $15M 497k 30.62
Urovant Sciences 0.1 $16M 1.0M 15.51
Aeglea Biotherapeutics 0.1 $13M 1.7M 7.64
Hookipa Pharma Inc equity (HOOK) 0.1 $11M 893k 12.23
Cabaletta Bio (CABA) 0.1 $8.9M 636k 13.97
Sangamo Biosciences (SGMO) 0.0 $8.4M 1000k 8.37
Abeona Therapeutics 0.0 $7.5M 2.3M 3.27
Reata Pharmaceuticals Inc Cl A 0.0 $8.4M 41k 204.43
Protagonist Therapeutics (PTGX) 0.0 $8.3M 1.2M 7.05
Fulgent Genetics (FLGT) 0.0 $7.3M 569k 12.90
Inflarx Nv (IFRX) 0.0 $7.0M 1.8M 3.96
Idera Pharmaceuticals 0.0 $8.4M 4.6M 1.82
Nextcure (NXTC) 0.0 $8.4M 150k 56.33
Mirum Pharmaceuticals (MIRM) 0.0 $8.2M 333k 24.52
Catalyst Pharmaceutical Partners (CPRX) 0.0 $5.0M 1.3M 3.75
Matinas Biopharma Holdings, In (MTNB) 0.0 $6.0M 2.6M 2.27
Syros Pharmaceuticals 0.0 $4.8M 690k 6.91
Albireo Pharma 0.0 $6.4M 250k 25.42
Constellation Pharmceticls I 0.0 $6.3M 133k 47.11
Aravive (ARAV) 0.0 $5.9M 433k 13.67
Millendo Therapeutics 0.0 $5.6M 833k 6.74
Orchard Therapeutics Plc ads 0.0 $5.6M 406k 13.75
Bluebird Bio (BLUE) 0.0 $3.5M 40k 87.75
Bellicum Pharma 0.0 $3.5M 2.7M 1.29
Viking Therapeutics (VKTX) 0.0 $3.4M 425k 8.02
G1 Therapeutics (GTHX) 0.0 $3.4M 127k 26.43
Molecular Templates 0.0 $4.4M 317k 13.98
Evofem Biosciences 0.0 $4.7M 757k 6.17
Menlo Therapeutics 0.0 $3.2M 700k 4.64
Crinetics Pharmaceuticals In (CRNX) 0.0 $4.4M 175k 25.09
Marker Therapeutics Ord 0.0 $4.3M 1.5M 2.88
Y Mabs Therapeutics (YMAB) 0.0 $4.3M 139k 31.25
Harpoon Therapeutics 0.0 $3.2M 214k 14.79
Ngm Biopharmaceuticals (NGM) 0.0 $4.6M 250k 18.49
Galmed Pharmaceuticals 0.0 $1.2M 216k 5.78
Trillium Therapeutics, Inc. Cmn 0.0 $1.1M 1.1M 1.03
Galapagos Nv- (GLPG) 0.0 $2.7M 13k 206.85
Cytomx Therapeutics (CTMX) 0.0 $1.6M 194k 8.31
Intellia Therapeutics (NTLA) 0.0 $1.9M 129k 14.67
Spring Bk Pharmaceuticals In 0.0 $969k 613k 1.58
Leap Therapeutics 0.0 $1.1M 979k 1.12
Anaptysbio Inc Common (ANAB) 0.0 $1.8M 113k 16.25
Arcus Biosciences Incorporated (RCUS) 0.0 $1.2M 122k 10.10
Autolus Therapeutics Plc spon ads (AUTL) 0.0 $2.1M 157k 13.20
Iveric Bio 0.0 $1.2M 142k 8.58
Ideaya Biosciences (IDYA) 0.0 $1.5M 200k 7.50
Infinity Pharmaceuticals (INFIQ) 0.0 $557k 580k 0.96
Adamas Pharmaceuticals 0.0 $654k 173k 3.79
Affimed Therapeutics B V (AFMD) 0.0 $548k 200k 2.74
Dynavax Technologies (DVAX) 0.0 $429k 75k 5.72
Sunesis Pharmaceuticals Inc Ne 0.0 $189k 557k 0.34