Baker Bros. Advisors as of Dec. 31, 2019
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 99 positions in its portfolio as reported in the December 2019 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seattle Genetics | 30.4 | $5.7B | 50M | 114.26 | |
| Incyte Corporation (INCY) | 14.8 | $2.8B | 32M | 87.32 | |
| Beigene (BGNE) | 10.4 | $2.0B | 12M | 165.76 | |
| ACADIA Pharmaceuticals (ACAD) | 9.3 | $1.7B | 41M | 42.78 | |
| Alexion Pharmaceuticals | 4.8 | $893M | 8.3M | 108.15 | |
| Kodiak Sciences (KOD) | 4.2 | $795M | 11M | 71.95 | |
| Amarin Corporation (AMRN) | 3.9 | $740M | 35M | 21.44 | |
| BioMarin Pharmaceutical (BMRN) | 3.4 | $642M | 7.6M | 84.55 | |
| Ascendis Pharma A S (ASND) | 2.5 | $472M | 3.4M | 139.12 | |
| EXACT Sciences Corporation (EXAS) | 1.3 | $239M | 2.6M | 92.48 | |
| Mirati Therapeutics | 0.9 | $168M | 1.3M | 128.86 | |
| Argenx Se (ARGX) | 0.9 | $164M | 1.0M | 160.52 | |
| Dbv Technologies S A | 0.8 | $156M | 15M | 10.70 | |
| Invitae (NVTAQ) | 0.8 | $147M | 9.1M | 16.13 | |
| Heron Therapeutics (HRTX) | 0.8 | $141M | 6.0M | 23.50 | |
| Neurocrine Biosciences (NBIX) | 0.7 | $135M | 1.3M | 107.49 | |
| Myokardia | 0.7 | $129M | 1.8M | 72.88 | |
| Igm Biosciences (IGMS) | 0.6 | $120M | 3.1M | 38.16 | |
| Madrigal Pharmaceuticals (MDGL) | 0.6 | $107M | 1.2M | 91.11 | |
| Ra Pharmaceuticals | 0.5 | $98M | 2.1M | 46.93 | |
| Principia Biopharma | 0.5 | $98M | 1.8M | 54.78 | |
| Axsome Therapeutics (AXSM) | 0.5 | $86M | 830k | 103.36 | |
| Zymeworks | 0.4 | $78M | 1.7M | 45.46 | |
| Tricida | 0.4 | $74M | 2.0M | 37.74 | |
| Rhythm Pharmaceuticals (RYTM) | 0.3 | $62M | 2.7M | 22.96 | |
| Insmed (INSM) | 0.3 | $58M | 2.4M | 23.88 | |
| Krystal Biotech (KRYS) | 0.3 | $57M | 1.0M | 55.38 | |
| Atreca Inc Cl A (BCEL) | 0.3 | $55M | 3.5M | 15.47 | |
| Audentes Therapeutics | 0.3 | $48M | 805k | 59.84 | |
| Neurocrine Biosciences Inc Note 2.250 5/1 | 0.2 | $47M | 31M | 1.53 | |
| Cerus Corporation (CERS) | 0.2 | $45M | 11M | 4.22 | |
| Neoleukin Therapeutics | 0.2 | $42M | 3.4M | 12.32 | |
| Gw Pharmaceuticals Plc ads | 0.2 | $39M | 371k | 104.56 | |
| BioCryst Pharmaceuticals (BCRX) | 0.2 | $38M | 11M | 3.45 | |
| Uniqure Nv (QURE) | 0.2 | $37M | 518k | 71.66 | |
| Aurinia Pharmaceuticals (AUPH) | 0.2 | $35M | 1.7M | 20.26 | |
| Adaptive Biotechnologies Cor (ADPT) | 0.2 | $33M | 1.1M | 29.92 | |
| Assembly Biosciences | 0.2 | $32M | 1.5M | 20.46 | |
| Allakos (ALLK) | 0.2 | $32M | 340k | 95.36 | |
| Chemocentryx | 0.2 | $29M | 739k | 39.55 | |
| Kiniksa Pharmaceuticals | 0.2 | $31M | 2.8M | 11.06 | |
| Merus N V (MRUS) | 0.1 | $29M | 2.0M | 14.08 | |
| Urogen Pharma (URGN) | 0.1 | $28M | 832k | 33.37 | |
| Aimmune Therapeutics | 0.1 | $23M | 674k | 33.47 | |
| Frequency Therapeutics | 0.1 | $22M | 1.2M | 17.53 | |
| Alkermes (ALKS) | 0.1 | $16M | 793k | 20.40 | |
| Xencor (XNCR) | 0.1 | $15M | 428k | 34.39 | |
| Biomarin Pharma Inc convertible/ | 0.1 | $16M | 15M | 1.06 | |
| Apellis Pharmaceuticals (APLS) | 0.1 | $15M | 497k | 30.62 | |
| Urovant Sciences | 0.1 | $16M | 1.0M | 15.51 | |
| Aeglea Biotherapeutics | 0.1 | $13M | 1.7M | 7.64 | |
| Hookipa Pharma Inc equity | 0.1 | $11M | 893k | 12.23 | |
| Cabaletta Bio (CABA) | 0.1 | $8.9M | 636k | 13.97 | |
| Sangamo Biosciences (SGMO) | 0.0 | $8.4M | 1000k | 8.37 | |
| Abeona Therapeutics | 0.0 | $7.5M | 2.3M | 3.27 | |
| Reata Pharmaceuticals Inc Cl A | 0.0 | $8.4M | 41k | 204.43 | |
| Protagonist Therapeutics (PTGX) | 0.0 | $8.3M | 1.2M | 7.05 | |
| Fulgent Genetics (FLGT) | 0.0 | $7.3M | 569k | 12.90 | |
| Inflarx Nv (IFRX) | 0.0 | $7.0M | 1.8M | 3.96 | |
| Idera Pharmaceuticals | 0.0 | $8.4M | 4.6M | 1.82 | |
| Nextcure (NXTC) | 0.0 | $8.4M | 150k | 56.33 | |
| Mirum Pharmaceuticals (MIRM) | 0.0 | $8.2M | 333k | 24.52 | |
| Catalyst Pharmaceutical Partners (CPRX) | 0.0 | $5.0M | 1.3M | 3.75 | |
| Matinas Biopharma Holdings, In (MTNB) | 0.0 | $6.0M | 2.6M | 2.27 | |
| Syros Pharmaceuticals | 0.0 | $4.8M | 690k | 6.91 | |
| Albireo Pharma | 0.0 | $6.4M | 250k | 25.42 | |
| Constellation Pharmceticls I | 0.0 | $6.3M | 133k | 47.11 | |
| Aravive | 0.0 | $5.9M | 433k | 13.67 | |
| Millendo Therapeutics | 0.0 | $5.6M | 833k | 6.74 | |
| Orchard Therapeutics Plc ads | 0.0 | $5.6M | 406k | 13.75 | |
| Bluebird Bio (BLUE) | 0.0 | $3.5M | 40k | 87.75 | |
| Bellicum Pharma | 0.0 | $3.5M | 2.7M | 1.29 | |
| Viking Therapeutics (VKTX) | 0.0 | $3.4M | 425k | 8.02 | |
| G1 Therapeutics | 0.0 | $3.4M | 127k | 26.43 | |
| Molecular Templates | 0.0 | $4.4M | 317k | 13.98 | |
| Evofem Biosciences | 0.0 | $4.7M | 757k | 6.17 | |
| Menlo Therapeutics | 0.0 | $3.2M | 700k | 4.64 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.0 | $4.4M | 175k | 25.09 | |
| Marker Therapeutics Ord | 0.0 | $4.3M | 1.5M | 2.88 | |
| Y Mabs Therapeutics (YMAB) | 0.0 | $4.3M | 139k | 31.25 | |
| Harpoon Therapeutics | 0.0 | $3.2M | 214k | 14.79 | |
| Ngm Biopharmaceuticals | 0.0 | $4.6M | 250k | 18.49 | |
| Galmed Pharmaceuticals | 0.0 | $1.2M | 216k | 5.78 | |
| Trillium Therapeutics, Inc. Cmn | 0.0 | $1.1M | 1.1M | 1.03 | |
| Galapagos Nv- (GLPG) | 0.0 | $2.7M | 13k | 206.85 | |
| Cytomx Therapeutics (CTMX) | 0.0 | $1.6M | 194k | 8.31 | |
| Intellia Therapeutics (NTLA) | 0.0 | $1.9M | 129k | 14.67 | |
| Spring Bk Pharmaceuticals In | 0.0 | $969k | 613k | 1.58 | |
| Leap Therapeutics | 0.0 | $1.1M | 979k | 1.12 | |
| Anaptysbio Inc Common (ANAB) | 0.0 | $1.8M | 113k | 16.25 | |
| Arcus Biosciences Incorporated (RCUS) | 0.0 | $1.2M | 122k | 10.10 | |
| Autolus Therapeutics Plc spon ads (AUTL) | 0.0 | $2.1M | 157k | 13.20 | |
| Iveric Bio | 0.0 | $1.2M | 142k | 8.58 | |
| Ideaya Biosciences (IDYA) | 0.0 | $1.5M | 200k | 7.50 | |
| Infinity Pharmaceuticals (INFIQ) | 0.0 | $557k | 580k | 0.96 | |
| Adamas Pharmaceuticals | 0.0 | $654k | 173k | 3.79 | |
| Affimed Therapeutics B V | 0.0 | $548k | 200k | 2.74 | |
| Dynavax Technologies (DVAX) | 0.0 | $429k | 75k | 5.72 | |
| Sunesis Pharmaceuticals Inc Ne | 0.0 | $189k | 557k | 0.34 |
