Baker Bros. Advisors as of Sept. 30, 2022
Portfolio Holdings for Baker Bros. Advisors
Baker Bros. Advisors holds 115 positions in its portfolio as reported in the September 2022 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Seagen | 42.0 | $6.4B | 47M | 136.83 | |
| Incyte Corporation (INCY) | 15.8 | $2.4B | 36M | 66.64 | |
| BeiGene Sponsored Adr (BGNE) | 10.3 | $1.6B | 12M | 134.82 | |
| ACADIA Pharmaceuticals (ACAD) | 4.5 | $686M | 42M | 16.36 | |
| BioMarin Pharmaceutical (BMRN) | 4.2 | $646M | 7.6M | 84.77 | |
| Ascendis Pharma A/S Sponsored Adr (ASND) | 3.3 | $501M | 4.9M | 103.26 | |
| Global Blood Therapeutics In | 1.7 | $254M | 3.7M | 68.10 | |
| BioCryst Pharmaceuticals (BCRX) | 1.0 | $160M | 13M | 12.60 | |
| Rhythm Pharmaceuticals (RYTM) | 1.0 | $149M | 6.1M | 24.50 | |
| Kodiak Sciences (KOD) | 0.9 | $134M | 17M | 7.74 | |
| Immunocore Holdings Ads (IMCR) | 0.8 | $118M | 2.5M | 46.94 | |
| Abcellera Biologics (ABCL) | 0.7 | $103M | 11M | 9.89 | |
| argenx SE Sponsored Adr (ARGX) | 0.6 | $99M | 280k | 353.05 | |
| Mirati Therapeutics | 0.6 | $99M | 1.4M | 69.84 | |
| Madrigal Pharmaceuticals (MDGL) | 0.6 | $97M | 1.5M | 64.99 | |
| Chemocentryx | 0.6 | $93M | 1.8M | 51.66 | |
| Travere Therapeutics (TVTX) | 0.5 | $81M | 3.3M | 24.64 | |
| Akero Therapeutics (AKRO) | 0.5 | $81M | 2.4M | 34.05 | |
| Entrada Therapeutics (TRDA) | 0.5 | $77M | 4.9M | 15.76 | |
| Igm Biosciences (IGMS) | 0.5 | $72M | 3.2M | 22.74 | |
| Replimune Group (REPL) | 0.4 | $67M | 3.9M | 17.27 | |
| Prelude Therapeutics (PRLD) | 0.4 | $67M | 10M | 6.61 | |
| Kymera Therapeutics (KYMR) | 0.4 | $63M | 2.9M | 21.77 | |
| Horizon Therapeutics Public SHS | 0.4 | $60M | 970k | 61.89 | |
| Cerus Corporation (CERS) | 0.4 | $58M | 16M | 3.60 | |
| Nurix Therapeutics (NRIX) | 0.3 | $51M | 3.9M | 13.03 | |
| Chinook Therapeutics | 0.3 | $50M | 2.5M | 19.66 | |
| Verve Therapeutics (VERV) | 0.3 | $49M | 1.4M | 34.35 | |
| Immatics SHS (IMTX) | 0.3 | $44M | 4.4M | 10.00 | |
| Forma Therapeutics Holdings SHS | 0.2 | $38M | 1.9M | 19.95 | |
| Insmed Incorporated Note 0.75% 6/1/2028 (Principal) | 0.2 | $36M | 40M | 0.91 | |
| Kiniksa Pharmaceuticals Com Cl A | 0.2 | $36M | 2.8M | 12.84 | |
| Heron Therapeutics (HRTX) | 0.2 | $34M | 8.1M | 4.22 | |
| Aerovate Therapeutics (AVTE) | 0.2 | $33M | 2.0M | 16.58 | |
| 2seventy Bio (TSVT) | 0.2 | $30M | 2.1M | 14.55 | |
| Krystal Biotech (KRYS) | 0.2 | $29M | 422k | 69.70 | |
| Xenon Pharmaceuticals (XENE) | 0.2 | $27M | 752k | 36.10 | |
| Cincor Pharma | 0.2 | $27M | 807k | 32.82 | |
| DBV Technologies Sponsored Adr | 0.2 | $26M | 15M | 1.77 | |
| Ideaya Biosciences (IDYA) | 0.2 | $25M | 1.7M | 14.92 | |
| Design Therapeutics (DSGN) | 0.2 | $24M | 1.4M | 16.72 | |
| Verastem | 0.2 | $23M | 27M | 0.85 | |
| Altimmune (ALT) | 0.1 | $23M | 1.8M | 12.77 | |
| Invitae (NVTAQ) | 0.1 | $21M | 8.4M | 2.46 | |
| Biomea Fusion (BMEA) | 0.1 | $21M | 2.1M | 9.78 | |
| Bicycle Therapeutics Sponsored Ads (BCYC) | 0.1 | $20M | 844k | 23.26 | |
| Ultragenyx Pharmaceutical (RARE) | 0.1 | $20M | 471k | 41.41 | |
| Instil Bio | 0.1 | $19M | 3.9M | 4.84 | |
| Female Health (VERU) | 0.1 | $19M | 1.6M | 11.52 | |
| Relmada Therapeutics (RLMD) | 0.1 | $18M | 495k | 37.02 | |
| Alkermes SHS (ALKS) | 0.1 | $18M | 815k | 22.33 | |
| Denali Therapeutics (DNLI) | 0.1 | $18M | 589k | 30.69 | |
| Opthea Sponsored Ads (OPT) | 0.1 | $17M | 2.7M | 6.20 | |
| Bluebird Bio (BLUE) | 0.1 | $16M | 2.5M | 6.33 | |
| Crinetics Pharmaceuticals In (CRNX) | 0.1 | $14M | 736k | 19.64 | |
| Aadi Bioscience (AADI) | 0.1 | $14M | 990k | 14.13 | |
| Tricida | 0.1 | $14M | 1.3M | 10.48 | |
| Affimed Therapeutics B V | 0.1 | $14M | 6.6M | 2.06 | |
| Dice Therapeutics | 0.1 | $12M | 588k | 20.28 | |
| Anaptysbio Inc Common (ANAB) | 0.1 | $11M | 427k | 25.51 | |
| Fibrogen (FGEN) | 0.1 | $11M | 816k | 13.01 | |
| Adaptimmune Therapeutics Sponsored Adr (ADAP) | 0.1 | $11M | 9.8M | 1.07 | |
| Zymeworks | 0.1 | $11M | 1.7M | 6.15 | |
| Point Biopharma Global | 0.1 | $9.0M | 1.2M | 7.73 | |
| Tscan Therapeutics (TCRX) | 0.1 | $8.5M | 2.8M | 3.05 | |
| Invitae Corporation Note 2.0% 9/1/2024 (Principal) | 0.1 | $8.1M | 10M | 0.79 | |
| Cymabay Therapeutics | 0.0 | $7.6M | 2.2M | 3.50 | |
| Vera Therapeutics Cl A (VERA) | 0.0 | $7.1M | 333k | 21.31 | |
| Pacific Biosciences of California (PACB) | 0.0 | $6.5M | 1.1M | 5.81 | |
| Fulgent Genetics (FLGT) | 0.0 | $6.4M | 167k | 38.12 | |
| Amarin Corporation Sponsored Adr (AMRN) | 0.0 | $5.9M | 5.4M | 1.09 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $5.9M | 2.6M | 2.26 | |
| Vor Biopharma (VOR) | 0.0 | $5.8M | 1.5M | 3.98 | |
| Reata Pharmaceuticals Cl A | 0.0 | $5.6M | 224k | 25.13 | |
| Atreca Cl A Com (BCEL) | 0.0 | $5.5M | 3.5M | 1.57 | |
| Nkarta (NKTX) | 0.0 | $5.3M | 400k | 13.16 | |
| Talis Biomedical Corp | 0.0 | $5.2M | 7.6M | 0.68 | |
| Kronos Bio (KRON) | 0.0 | $5.2M | 1.5M | 3.35 | |
| Cyteir Therapeutics | 0.0 | $5.1M | 2.6M | 1.92 | |
| Surrozen | 0.0 | $5.1M | 2.5M | 2.02 | |
| Edgewise Therapeutics (EWTX) | 0.0 | $4.9M | 500k | 9.84 | |
| Fate Therapeutics (FATE) | 0.0 | $4.8M | 216k | 22.41 | |
| Stoke Therapeutics (STOK) | 0.0 | $4.7M | 369k | 12.84 | |
| Natera (NTRA) | 0.0 | $4.4M | 100k | 43.82 | |
| Revolution Medicines (RVMD) | 0.0 | $4.4M | 222k | 19.72 | |
| Allakos (ALLK) | 0.0 | $4.3M | 703k | 6.12 | |
| Eiger Biopharmaceuticals | 0.0 | $4.1M | 540k | 7.53 | |
| Pmv Pharmaceuticals (PMVP) | 0.0 | $3.8M | 322k | 11.90 | |
| Century Therapeutics (IPSC) | 0.0 | $3.7M | 371k | 9.89 | |
| Hookipa Pharma Inc equity | 0.0 | $3.2M | 2.4M | 1.34 | |
| Athira Pharma (ATHA) | 0.0 | $3.1M | 1.0M | 2.97 | |
| Macrogenics (MGNX) | 0.0 | $3.1M | 893k | 3.46 | |
| Iteos Therapeutics (ITOS) | 0.0 | $2.9M | 150k | 19.05 | |
| Atara Biotherapeutics | 0.0 | $2.8M | 744k | 3.78 | |
| Tango Therapeutics (TNGX) | 0.0 | $2.7M | 750k | 3.62 | |
| Syndax Pharmaceuticals (SNDX) | 0.0 | $2.7M | 111k | 24.03 | |
| Otonomy | 0.0 | $2.5M | 8.4M | 0.29 | |
| Neoleukin Therapeutics | 0.0 | $2.4M | 3.8M | 0.64 | |
| Aligos Therapeutics (ALGS) | 0.0 | $2.3M | 2.1M | 1.10 | |
| Alector (ALEC) | 0.0 | $2.3M | 239k | 9.46 | |
| Aeglea Biotherapeutics | 0.0 | $1.8M | 3.4M | 0.53 | |
| Tcr2 Therapeutics Inc cs | 0.0 | $1.4M | 753k | 1.80 | |
| Atyr Pharma (ATYR) | 0.0 | $604k | 201k | 3.00 | |
| Protara Therapeutics Com Stk (TARA) | 0.0 | $591k | 200k | 2.96 | |
| Kezar Life Sciences (KZR) | 0.0 | $533k | 62k | 8.60 | |
| Leap Therapeutics | 0.0 | $493k | 560k | 0.88 | |
| Cabaletta Bio (CABA) | 0.0 | $430k | 662k | 0.65 | |
| Insmed Incorporated Com Par $.01 (INSM) | 0.0 | $430k | 20k | 21.55 | |
| Foghorn Therapeutics (FHTX) | 0.0 | $386k | 45k | 8.57 | |
| Genetron Holdings Ads | 0.0 | $356k | 455k | 0.78 | |
| Vincera Pharma (VINC) | 0.0 | $333k | 241k | 1.38 | |
| Sera Prognostics Class A Com (SERA) | 0.0 | $322k | 202k | 1.60 | |
| Bellicum Pharmaceuticals | 0.0 | $299k | 249k | 1.20 | |
| Surrozen W Exp 8/11/2026 (SRZNW) | 0.0 | $154k | 833k | 0.18 | |
| Logicbio Therapeutics | 0.0 | $38k | 139k | 0.27 |
