Baker Bros. Advisors

Baker Bros. Advisors as of March 31, 2011

Portfolio Holdings for Baker Bros. Advisors

Baker Bros. Advisors holds 51 positions in its portfolio as reported in the March 2011 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Genomic Health 13.3 $84M 7.5M 11.21
Ardea Biosciences 11.5 $73M 6.0M 12.06
InterMune 11.1 $70M 1.5M 47.19
Auxilium 9.0 $57M 7.3M 7.76
Alere 7.2 $46M 1.2M 39.14
Pharmasset 6.0 $38M 1.8M 21.62
Halozyme Therapeutics (HALO) 4.2 $27M 3.9M 6.71
Ym Biosciences 3.8 $24M 9.1M 2.64
BioCryst Pharmaceuticals (BCRX) 3.3 $21M 5.6M 3.79
Pharmacyclics 2.0 $13M 2.2M 5.89
Exelixis (EXEL) 1.9 $12M 1.1M 11.33
Medivation 1.7 $11M 583k 18.64
Micromet 1.7 $11M 1.9M 5.60
BioMarin Pharmaceutical (BMRN) 1.6 $9.8M 388k 25.13
Adolor Corporation (ADLR) 1.5 $9.7M 6.9M 1.40
Biomarin Pharmaceutical Inc note 1.875% 4/2 1.4 $8.7M 6.4M 1.36
Trimeris 1.4 $8.7M 3.5M 2.51
BioDelivery Sciences International 1.3 $8.5M 2.4M 3.53
Amicus Therapeutics (FOLD) 1.3 $8.0M 1.1M 7.09
Human Genome cv 2.25% 1.1 $7.2M 4.5M 1.60
Anacor Pharmaceuticals 1.1 $7.2M 1.0M 6.92
ACADIA Pharmaceuticals (ACAD) 1.1 $7.1M 4.4M 1.62
Alere Inc note 3.000% 5/1 1.1 $6.8M 6.0M 1.13
Alkermes 1.0 $6.5M 505k 12.95
Dendreon Corp note 1.0 $6.4M 6.0M 1.06
Achillion Pharmaceuticals 0.9 $5.7M 802k 7.15
Threshold Pharma 0.9 $5.7M 3.7M 1.54
ZIOPHARM Oncology 0.9 $5.6M 890k 6.25
Anthera Pharmaceuticals 0.9 $5.4M 800k 6.75
GTx 0.7 $4.5M 1.7M 2.57
Chelsea Therapeutics International 0.7 $4.3M 1.1M 3.88
Inhibitex 0.5 $3.4M 928k 3.62
Salix Pharmaceuticals 0.5 $2.9M 83k 35.03
AVANIR Pharmaceuticals 0.3 $2.0M 500k 4.08
XenoPort 0.3 $1.9M 313k 5.93
DepoMed 0.3 $1.8M 183k 10.04
Alnylam Pharmaceuticals (ALNY) 0.2 $1.6M 166k 9.56
A.P. Pharma (APPA) 0.2 $1.6M 6.9M 0.23
Xoma 0.2 $1.1M 400k 2.79
Ligand Pharmaceuticals 0.1 $836k 84k 10.00
Idera Pharmaceuticals 0.1 $761k 288k 2.64
Infinity Pharmaceuticals (INFIQ) 0.1 $628k 107k 5.88
Pozen 0.1 $618k 115k 5.37
Cumberland Pharmaceuticals (CPIX) 0.1 $533k 96k 5.53
Cadence Pharmaceuticals 0.1 $355k 39k 9.17
Alere 0.0 $202k 732.00 275.96
Cyclacel Pharmaceuticals Inc pfd conv ex 6% (CYCCP) 0.0 $96k 22k 4.29
Anadys Pharmaceuticals (ANDS) 0.0 $70k 61k 1.16
Amylin Pharmaceuticals Inc note 2.500% 4/1 0.0 $3.0k 3.0k 1.00
Aradigm Corporation (ARDM) 0.0 $18k 100k 0.18
VIA Pharmaceuticals (VIAP) 0.0 $6.2k 103k 0.06