Opaleye Management

Opaleye Management as of Dec. 31, 2024

Portfolio Holdings for Opaleye Management

Opaleye Management holds 39 positions in its portfolio as reported in the December 2024 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Harrow Health (HROW) 23.4 $134M 4.0M 33.55
Tg Therapeutics (TGTX) 11.9 $68M 2.3M 30.10
Codexis (CDXS) 7.4 $42M 8.8M 4.77
Eton Pharmaceuticals (ETON) 6.6 $38M 2.9M 13.32
Ocular Therapeutix (OCUL) 6.5 $37M 4.3M 8.54
Arvinas Ord (ARVN) 5.9 $34M 1.6M 20.70
Rhythm Pharmaceuticals (RYTM) 4.9 $28M 500k 55.98
Immunome (IMNM) 3.8 $22M 2.0M 10.62
Liquidia Corporation Com New (LQDA) 3.5 $20M 1.7M 11.76
Edgewise Therapeutics (EWTX) 2.2 $13M 480k 26.70
Ginkgo Bioworks Holdings Class A New (DNA) 2.1 $12M 1.2M 9.82
Cargo Therapeutics (CRGX) 1.9 $11M 750k 14.42
Protara Therapeutics Com Stk (TARA) 1.7 $9.6M 1.8M 5.28
Trevi Therapeutics (TRVI) 1.7 $9.5M 2.3M 4.12
Jasper Therapeutics Com New (JSPR) 1.5 $8.6M 400k 21.38
Newamsterdam Pharma Company Ordinary Shares (NAMS) 1.5 $8.4M 325k 25.70
Acelyrin 1.3 $7.2M 2.2M 3.21
Nurix Therapeutics (NRIX) 1.2 $7.1M 379k 18.84
Xoma Corp Del Com New (XOMA) 1.1 $6.6M 250k 26.28
Vaxcyte (PCVX) 1.1 $6.1M 75k 81.86
Gossamer Bio Note 5.000% 6/0 (Principal) 1.1 $6.1M 12M 0.53
Zentalis Pharmaceuticals (ZNTL) 0.9 $5.4M 1.8M 3.03
Biodesix (BDSX) 0.9 $5.3M 3.5M 1.53
Karyopharm Therapeutics Note 3.000%10/1 (Principal) 0.8 $4.7M 6.0M 0.78
Nuvalent Inc-a (NUVL) 0.8 $4.6M 59k 78.28
Gossamer Bio (GOSS) 0.7 $4.1M 4.5M 0.90
Protagonist Therapeutics (PTGX) 0.7 $4.1M 105k 38.60
Essa Pharma Com New (EPIX) 0.7 $4.0M 2.2M 1.79
Abcellera Biologics (ABCL) 0.5 $2.8M 965k 2.93
Urogen Pharma (URGN) 0.4 $2.3M 220k 10.65
Rezolute Com New (RZLT) 0.4 $2.3M 465k 4.90
Immatics Nv Ordinary Shares (IMTX) 0.2 $1.2M 165k 7.11
Ibio Com New (IBIO) 0.2 $919k 375k 2.45
Lexeo Therapeutics (LXEO) 0.1 $855k 130k 6.58
Regenxbio Inc equity us cm (RGNX) 0.1 $618k 80k 7.73
Ventyx Biosciences (VTYX) 0.1 $613k 280k 2.19
Pepgen (PEPG) 0.1 $417k 110k 3.79
Stoke Therapeutics (STOK) 0.0 $276k 25k 11.03
Adagio Med Hldgs (ADGM) 0.0 $116k 111k 1.05