Opaleye Management as of March 31, 2025
Portfolio Holdings for Opaleye Management
Opaleye Management holds 45 positions in its portfolio as reported in the March 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Harrow Health (HROW) | 23.4 | $105M | 4.0M | 26.60 | |
| Eton Pharmaceuticals (ETON) | 8.2 | $37M | 2.9M | 12.98 | |
| Sanuwave Health (SNWV) | 7.7 | $34M | 972k | 35.37 | |
| Liquidia Corporation Com New (LQDA) | 7.4 | $33M | 2.3M | 14.75 | |
| Rhythm Pharmaceuticals (RYTM) | 5.8 | $26M | 490k | 52.97 | |
| Codexis (CDXS) | 5.7 | $26M | 9.5M | 2.69 | |
| Immunome (IMNM) | 5.3 | $24M | 3.6M | 6.73 | |
| Tg Therapeutics (TGTX) | 4.7 | $21M | 535k | 39.43 | |
| Arvinas Ord (ARVN) | 3.1 | $14M | 2.0M | 7.02 | |
| Ocular Therapeutix (OCUL) | 2.6 | $12M | 1.6M | 7.33 | |
| Edgewise Therapeutics (EWTX) | 1.9 | $8.7M | 395k | 22.00 | |
| Protara Therapeutics Com Stk (TARA) | 1.6 | $7.4M | 1.7M | 4.26 | |
| Ginkgo Bioworks Holdings Class A New (DNA) | 1.5 | $6.8M | 1.2M | 5.70 | |
| Gossamer Bio Note 5.000% 6/0 (Principal) | 1.4 | $6.3M | 12M | 0.55 | |
| Anika Therapeutics (ANIK) | 1.3 | $5.9M | 395k | 15.03 | |
| Protagonist Therapeutics (PTGX) | 1.1 | $5.1M | 105k | 48.36 | |
| Xoma Corp Del Com New (XOMA) | 1.1 | $5.0M | 253k | 19.93 | |
| Trevi Therapeutics (TRVI) | 1.1 | $5.0M | 795k | 6.29 | |
| Palvella Therapeutics Inc Ne (PVLA) | 1.1 | $4.8M | 172k | 27.99 | |
| Gossamer Bio (GOSS) | 1.1 | $4.7M | 4.3M | 1.10 | |
| Anaptysbio Inc Common (ANAB) | 1.0 | $4.7M | 251k | 18.59 | |
| Karyopharm Therapeutics Note 3.000%10/1 (Principal) | 1.0 | $4.6M | 6.0M | 0.76 | |
| Disc Medicine (IRON) | 0.9 | $4.2M | 85k | 49.64 | |
| Larimar Therapeutics (LRMR) | 0.9 | $4.1M | 1.9M | 2.15 | |
| Cg Oncology (CGON) | 0.9 | $4.0M | 164k | 24.49 | |
| Acelyrin | 0.9 | $4.0M | 1.6M | 2.47 | |
| Avita Therapeutics (RCEL) | 0.8 | $3.6M | 440k | 8.14 | |
| Essa Pharma Com New (EPIX) | 0.8 | $3.5M | 2.2M | 1.58 | |
| Zentalis Pharmaceuticals (ZNTL) | 0.7 | $3.2M | 2.0M | 1.59 | |
| Cargo Therapeutics (CRGX) | 0.6 | $2.7M | 667k | 4.07 | |
| Zymeworks Del (ZYME) | 0.5 | $2.1M | 175k | 11.91 | |
| Biodesix (BDSX) | 0.4 | $2.0M | 3.2M | 0.63 | |
| Stoke Therapeutics (STOK) | 0.4 | $2.0M | 300k | 6.65 | |
| Mbx Biosciences (MBX) | 0.4 | $1.8M | 250k | 7.38 | |
| Optinose Com New | 0.4 | $1.8M | 193k | 9.17 | |
| Ocuphire Pharma (IRD) | 0.3 | $1.5M | 1.2M | 1.32 | |
| Ibio Com New (IBIO) | 0.3 | $1.5M | 375k | 4.02 | |
| Kiniksa Pharmaceuticals Intl Ord Shrs Cl A (KNSA) | 0.3 | $1.4M | 63k | 22.21 | |
| Nurix Therapeutics (NRIX) | 0.3 | $1.4M | 115k | 11.88 | |
| Rezolute Com New (RZLT) | 0.3 | $1.3M | 465k | 2.90 | |
| Sangamo Biosciences (SGMO) | 0.2 | $692k | 1.1M | 0.66 | |
| Pepgen (PEPG) | 0.1 | $590k | 420k | 1.41 | |
| Journey Med Corp (DERM) | 0.1 | $409k | 69k | 5.90 | |
| Ventyx Biosciences (VTYX) | 0.0 | $219k | 190k | 1.15 | |
| Adagio Med Hldgs (ADGM) | 0.0 | $92k | 111k | 0.83 |
