Opaleye Management as of June 30, 2025
Portfolio Holdings for Opaleye Management
Opaleye Management holds 41 positions in its portfolio as reported in the June 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Harrow Health (HROW) | 24.1 | $119M | 3.9M | 30.54 | |
| Eton Pharmaceuticals (ETON) | 8.2 | $41M | 2.9M | 14.25 | |
| Immunome (IMNM) | 6.6 | $33M | 3.5M | 9.30 | |
| Sanuwave Health (SNWV) | 6.5 | $32M | 980k | 32.86 | |
| Liquidia Corporation Com New (LQDA) | 6.2 | $31M | 2.5M | 12.46 | |
| Codexis (CDXS) | 6.2 | $31M | 13M | 2.44 | |
| Rhythm Pharmaceuticals (RYTM) | 6.1 | $30M | 475k | 63.19 | |
| Tg Therapeutics (TGTX) | 3.9 | $19M | 535k | 35.99 | |
| Ocular Therapeutix (OCUL) | 3.0 | $15M | 1.6M | 9.28 | |
| Arvinas Ord (ARVN) | 2.5 | $12M | 1.7M | 7.36 | |
| Larimar Therapeutics (LRMR) | 2.4 | $12M | 4.1M | 2.89 | |
| Disc Medicine (IRON) | 2.0 | $9.9M | 186k | 52.96 | |
| Sarepta Therapeutics (SRPT) | 1.7 | $8.6M | 500k | 17.10 | |
| Vigil Neuroscience (VIGL) | 1.6 | $8.0M | 1.0M | 7.95 | |
| Cg Oncology (CGON) | 1.4 | $6.9M | 266k | 26.00 | |
| Xoma Corp Del Com New (XOMA) | 1.3 | $6.4M | 255k | 25.20 | |
| Edgewise Therapeutics (EWTX) | 1.3 | $6.4M | 490k | 13.11 | |
| Stoke Therapeutics (STOK) | 1.3 | $6.4M | 562k | 11.35 | |
| Anika Therapeutics (ANIK) | 1.3 | $6.2M | 589k | 10.58 | |
| Gossamer Bio Note 5.000% 6/0 (Principal) | 1.2 | $5.9M | 12M | 0.52 | |
| Protagonist Therapeutics (PTGX) | 1.2 | $5.8M | 105k | 55.27 | |
| Ginkgo Bioworks Holdings Class A New (DNA) | 1.1 | $5.6M | 500k | 11.25 | |
| Karyopharm Therapeutics Note 3.000%10/1 (Principal) | 0.9 | $4.6M | 6.0M | 0.76 | |
| Gossamer Bio (GOSS) | 0.9 | $4.4M | 3.5M | 1.23 | |
| Rezolute Com New (RZLT) | 0.8 | $4.0M | 903k | 4.46 | |
| Revolution Medicines (RVMD) | 0.8 | $3.9M | 105k | 36.79 | |
| Essa Pharma Com New (EPIX) | 0.8 | $3.8M | 2.2M | 1.70 | |
| Cargo Therapeutics (CRGX) | 0.6 | $2.7M | 667k | 4.12 | |
| Mbx Biosciences (MBX) | 0.6 | $2.7M | 239k | 11.41 | |
| Zymeworks Del (ZYME) | 0.5 | $2.6M | 210k | 12.55 | |
| Protara Therapeutics Com Stk (TARA) | 0.5 | $2.6M | 855k | 3.03 | |
| Alumis (ALMS) | 0.5 | $2.3M | 775k | 3.00 | |
| Zentalis Pharmaceuticals (ZNTL) | 0.5 | $2.2M | 1.9M | 1.16 | |
| Trevi Therapeutics (TRVI) | 0.4 | $2.1M | 390k | 5.47 | |
| Avita Therapeutics (RCEL) | 0.4 | $2.1M | 390k | 5.29 | |
| Ocuphire Pharma (IRD) | 0.2 | $1.1M | 1.2M | 0.94 | |
| Journey Med Corp (DERM) | 0.1 | $682k | 95k | 7.18 | |
| Elevation Oncology (ELEV) | 0.1 | $529k | 1.4M | 0.37 | |
| Ibio Com New (IBIO) | 0.1 | $285k | 375k | 0.76 | |
| Pepgen (PEPG) | 0.1 | $266k | 240k | 1.11 | |
| Adagio Med Hldgs (ADGM) | 0.0 | $144k | 111k | 1.30 |
