Opaleye Management

Opaleye Management as of Dec. 31, 2016

Portfolio Holdings for Opaleye Management

Opaleye Management holds 40 positions in its portfolio as reported in the December 2016 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Blueprint Medicines (BPMC) 14.5 $25M 880k 28.05
Axogen (AXGN) 10.4 $18M 2.0M 9.00
Ariad Pharmaceuticals 7.3 $12M 1.0M 12.44
Aevi Genomic 4.6 $7.8M 1.5M 5.18
Fibrogen (FGEN) 4.2 $7.1M 330k 21.40
Foamix Pharmaceuticals 3.2 $5.5M 495k 11.10
Agios Pharmaceuticals (AGIO) 3.2 $5.4M 130k 41.73
Codexis (CDXS) 3.2 $5.4M 1.2M 4.60
Chimerix (CMRX) 3.2 $5.4M 1.2M 4.60
Aquinox Pharmaceuticals 3.0 $5.1M 310k 16.51
Theravance Biopharma (TBPH) 3.0 $5.0M 158k 31.88
Momenta Pharmaceuticals 2.9 $5.0M 330k 15.05
Adamas Pharmaceuticals 2.8 $4.8M 285k 16.90
Cara Therapeutics (CARA) 2.6 $4.4M 475k 9.29
Prothena (PRTA) 2.4 $4.1M 83k 49.19
Loxo Oncology 2.4 $4.0M 125k 32.11
Eagle Pharmaceuticals (EGRX) 2.3 $4.0M 50k 79.34
Edge Therapeutics 2.1 $3.5M 280k 12.50
Macrogenics (MGNX) 2.0 $3.5M 170k 20.44
Xenon Pharmaceuticals (XENE) 1.8 $3.1M 405k 7.70
Enanta Pharmaceuticals (ENTA) 1.8 $3.0M 90k 33.50
Strongbridge Bioph shs usd 1.6 $2.8M 1.2M 2.40
Omeros Corporation (OMER) 1.6 $2.6M 265k 9.92
Clearside Biomedical (CLSD) 1.4 $2.4M 270k 8.94
Lion Biotechnologies 1.2 $2.1M 300k 6.95
Abeona Therapeutics 1.1 $1.9M 400k 4.85
Cytomx Therapeutics (CTMX) 1.1 $1.9M 170k 10.99
Proteostasis Therapeutics In 1.1 $1.8M 150k 12.26
Imprimis Pharmaceuticals 1.1 $1.8M 720k 2.50
Sage Therapeutics (SAGE) 1.1 $1.8M 35k 51.06
Neuroderm Ltd F 1.0 $1.7M 115k 15.05
Wafergen Bio-systems 0.9 $1.6M 320k 4.93
Corium Intl 0.9 $1.5M 380k 4.06
Sangamo Biosciences (SGMO) 0.7 $1.2M 400k 3.05
Achaogen 0.6 $1.0M 80k 13.01
Protalix Biotherapeutics Inc note 4.500% 9/1 0.5 $869k 1.9M 0.45
Ocular Therapeutix (OCUL) 0.5 $783k 94k 8.37
Trillium Therapeutics, Inc. Cmn 0.4 $622k 110k 5.65
Biolinerx Ltd-spons 0.1 $230k 250k 0.92
Agile Therapeutics 0.1 $85k 15k 5.67