OrbiMed Advisors

Orbimed Advisors as of March 31, 2026

Portfolio Holdings for Orbimed Advisors

Orbimed Advisors holds 110 positions in its portfolio as reported in the March 2026 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Edgewise Therapeutics (EWTX) 9.5 $489M 16M 31.50
Enliven Therapeutics (ELVN) 6.0 $312M 8.0M 39.20
Avita Therapeutics (RCEL) 5.9 $303M 82M 3.70
Mdxhealth Sa Shs New Call Option (MDXH) 5.5 $286M 124M 2.30
Eli Lilly & Co. (LLY) 4.2 $218M 237k 919.77
Sinovac Biotech SHS 3.6 $185M 2.7M 67.85
Boston Scientific Corporation (BSX) 2.9 $150M 2.4M 62.75
Sionna Therapeutics (SION) 2.7 $142M 3.5M 40.09
Astrazeneca Ord (AZN) 2.6 $132M 670k 197.22
Myriad Genetics (Principal) (MYGN) 2.4 $123M 125M 0.98
Mbx Biosciences (MBX) 2.1 $109M 3.6M 29.85
Corvus Pharmaceuticals (CRVS) 2.0 $105M 7.2M 14.63
Argenx Se Sponsored Adr (ARGX) 1.9 $100M 137k 730.25
Edwards Lifesciences (EW) 1.9 $99M 1.2M 80.08
Intuitive Surgical Com New (ISRG) 1.9 $96M 209k 460.99
Compass Therapeutics (CMPX) 1.6 $81M 15M 5.29
Merck & Co (MRK) 1.5 $80M 663k 120.29
Structure Therapeutics Sponsored Ads (GPCR) 1.4 $71M 1.5M 48.20
Arrivent Biopharma (AVBP) 1.4 $70M 3.0M 23.07
Disc Medicine (IRON) 1.3 $68M 1.1M 63.94
Silverback Therapeutics (SPRY) 1.3 $67M 8.3M 8.03
Cg Oncology (CGON) 1.2 $64M 948k 67.68
Xenon Pharmaceuticals (XENE) 1.2 $62M 1.1M 58.15
Stryker Corporation (SYK) 1.2 $60M 183k 328.59
Bristol Myers Squibb (BMY) 1.1 $56M 925k 60.65
Mineralys Therapeutics (MLYS) 1.1 $56M 2.1M 27.09
Praxis Precision Medicines I Com New (PRAX) 1.1 $56M 173k 322.19
Pfizer (PFE) 1.1 $55M 1.9M 28.08
Dyne Therapeutics (DYN) 1.0 $53M 2.9M 18.13
Natera (NTRA) 1.0 $52M 262k 199.99
Abivax Sa Sponsored Ads (ABVX) 1.0 $52M 466k 111.35
Upstream Bio (UPB) 1.0 $51M 5.7M 9.00
Danaher Corporation (DHR) 1.0 $50M 266k 189.60
Caris Life Sciences (CAI) 1.0 $50M 2.8M 17.88
Ascendis Pharma A/s Sponsored Adr (ASND) 0.8 $42M 182k 228.73
Shattuck Labs (STTK) 0.8 $41M 6.3M 6.43
Guardant Health (GH) 0.8 $40M 435k 92.37
Alnylam Pharmaceuticals (ALNY) 0.8 $39M 119k 330.87
Prelude Therapeutics (PRLD) 0.7 $37M 11M 3.42
Crinetics Pharmaceuticals In (CRNX) 0.7 $36M 999k 36.32
Axsome Therapeutics (AXSM) 0.7 $36M 214k 169.02
Uniqure Nv SHS (QURE) 0.7 $35M 2.1M 16.35
Oric Pharmaceuticals (ORIC) 0.7 $34M 2.7M 12.67
Anthem (ELV) 0.7 $34M 115k 292.75
Relmada Therapeutics (RLMD) 0.6 $33M 4.7M 6.96
Imagenebio Nonvoting 0.6 $31M 6.2M 5.00
Forte Biosciences Com New (FBRX) 0.6 $31M 1.2M 25.90
Trevi Therapeutics (TRVI) 0.6 $29M 2.5M 11.93
Esperion Therapeutics (ESPR) 0.6 $29M 11M 2.74
Neuropace (NPCE) 0.5 $28M 2.1M 13.15
Rhythm Pharmaceuticals (RYTM) 0.5 $27M 314k 86.97
Palvella Therapeutics Inc Ne (PVLA) 0.4 $23M 185k 124.65
Thermo Fisher Scientific (TMO) 0.4 $23M 47k 491.53
Syndax Pharmaceuticals (SNDX) 0.4 $23M 962k 23.36
Brightspring Health Svcs (BTSG) 0.4 $21M 498k 42.61
Lexeo Therapeutics (LXEO) 0.4 $21M 3.6M 5.74
Sutro Biopharma Com Shs (STRO) 0.4 $20M 801k 24.91
Nektar Therapeutics Com New (NKTR) 0.4 $20M 275k 71.95
Cybin Com New (HELP) 0.4 $18M 3.8M 4.80
Krystal Biotech (KRYS) 0.3 $18M 69k 258.32
Corbus Pharmaceuticals Hldgs Com New (CRBP) 0.3 $16M 1.7M 9.39
Urogen Pharma (URGN) 0.3 $16M 876k 17.98
Definium Therapeutics Com Shs (DFTX) 0.3 $15M 804k 18.90
Vera Therapeutics Cl A (VERA) 0.3 $15M 370k 40.23
Q32 Bio (QTTB) 0.3 $15M 2.3M 6.42
Aadi Bioscience (WHWK) 0.3 $14M 4.2M 3.45
Amgen (AMGN) 0.3 $14M 40k 351.85
Alignment Healthcare (ALHC) 0.3 $14M 791k 17.62
Eyepoint Com New (EYPT) 0.3 $14M 1.1M 12.89
Janux Therapeutics (JANX) 0.3 $14M 984k 13.90
BioCryst Pharmaceuticals (BCRX) 0.3 $14M 1.4M 9.52
Bicara Therapeutics (BCAX) 0.3 $13M 667k 19.89
Bioage Labs (BIOA) 0.2 $12M 712k 17.49
Cogent Biosciences (COGT) 0.2 $12M 322k 38.49
Alumis (ALMS) 0.2 $12M 548k 22.03
Regeneron Pharmaceuticals (REGN) 0.2 $11M 15k 772.64
Carlsmed (CARL) 0.2 $11M 1.3M 9.05
Biogen Idec (BIIB) 0.2 $11M 62k 183.33
Qiagen Nv Ord Shares Call Option (QGEN) 0.2 $10M 250k 40.04
Kiniksa Pharmaceuticals Intl Ord Shs Cl A (KNSA) 0.2 $8.7M 181k 48.15
Keros Therapeutics (KROS) 0.2 $8.4M 759k 11.04
Gilead Sciences (GILD) 0.2 $8.3M 60k 139.37
Heron Therapeutics (HRTX) 0.2 $7.9M 9.8M 0.80
Avalo Therapeutics Com New (AVTX) 0.1 $7.1M 475k 14.93
Tectonic Therapeutic (TECX) 0.1 $7.0M 227k 30.91
Adicet Bio Com New (ACET) 0.1 $7.0M 1.0M 6.81
Compass Pathways Sponsored Ads (CMPS) 0.1 $6.4M 1.2M 5.53
Pharvaris N V (PHVS) 0.1 $5.8M 205k 28.25
Alx Oncology Hldgs (ALXO) 0.1 $5.7M 2.9M 2.00
CryoLife (AORT) 0.1 $5.5M 151k 36.62
Inspiremd (NSPR) 0.1 $5.1M 3.1M 1.63
Revolution Medicines (RVMD) 0.1 $5.1M 52k 97.25
Adc Therapeutics Sa SHS (ADCT) 0.1 $4.9M 1.3M 3.75
Protagonist Therapeutics (PTGX) 0.1 $4.4M 42k 105.40
Palisade Bio (PALI) 0.1 $4.1M 2.3M 1.75
Alto Neuroscience Com Shs (ANRO) 0.1 $3.8M 168k 22.48
Savara (SVRA) 0.1 $3.5M 635k 5.46
Cullinan Oncology (CGEM) 0.1 $3.5M 243k 14.21
Soleno Therapeutics Call Option (SLNO) 0.1 $3.3M 100k 33.48
Ptc Therapeutics I (PTCT) 0.1 $3.3M 49k 68.13
Lifestance Health Group (LFST) 0.1 $3.2M 500k 6.37
Bright Minds Biosciences Com New (DRUG) 0.1 $2.9M 40k 72.97
Jade Biosciences Com New (JBIO) 0.1 $2.6M 185k 14.05
C4 Therapeutics Com Stk (CCCC) 0.0 $2.3M 856k 2.63
Kalvista Pharmaceuticals (KALV) 0.0 $1.9M 94k 20.13
Imagenebio (IMA) 0.0 $1.9M 379k 5.00
Vistagen Therapeutics Ord (VTGN) 0.0 $1.7M 3.1M 0.57
Ataibeckley Com Shs (ATAI) 0.0 $1.2M 347k 3.54
Cogent Biosciences Note 1.625%11/1 (Principal) 0.0 $1.2M 1.0M 1.22
Traws Pharma Com New (TRAW) 0.0 $1.1M 606k 1.83