Siren as of Sept. 30, 2024
Portfolio Holdings for Siren
Siren holds 110 positions in its portfolio as reported in the September 2024 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Kymera Therapeutics (KYMR) | 7.0 | $141M | 3.0M | 47.33 | |
| Beigene Sponsored Adr (BGNE) | 6.3 | $127M | 563k | 224.51 | |
| Scholar Rock Hldg Corp (SRRK) | 4.5 | $90M | 11M | 8.01 | |
| Bicara Therapeutics | 3.9 | $78M | 3.1M | 25.47 | |
| Argenx SE Sponsored Adr (ARGX) | 3.9 | $78M | 144k | 542.08 | |
| Crinetics Pharmaceuticals In (CRNX) | 3.3 | $67M | 1.3M | 51.10 | |
| Avidity Biosciences Ord (RNA) | 3.3 | $66M | 1.4M | 45.93 | |
| Apellis Pharmaceuticals (APLS) | 3.1 | $63M | 2.2M | 28.84 | |
| Lexicon Pharmaceuticals Com New (LXRX) | 3.1 | $61M | 39M | 1.57 | |
| Igm Biosciences (IGMS) | 2.8 | $55M | 3.3M | 16.54 | |
| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 2.6 | $52M | 3.3M | 15.99 | |
| Ascendis Pharma A/S Sponsored Adr (ASND) | 2.6 | $52M | 348k | 149.31 | |
| Silence Therapeutics Ads (SLN) | 2.6 | $52M | 2.8M | 18.18 | |
| Arrowhead Pharmaceuticals (ARWR) | 2.4 | $48M | 2.5M | 19.37 | |
| WAVE Life Sciences SHS (WVE) | 2.3 | $47M | 5.7M | 8.20 | |
| Springworks Therapeutics (SWTX) | 2.2 | $44M | 1.4M | 32.04 | |
| Dyne Therapeutics (DYN) | 2.0 | $41M | 1.1M | 35.92 | |
| Vera Therapeutics Cl A (VERA) | 1.9 | $37M | 838k | 44.20 | |
| Neumora Therapeutics (NMRA) | 1.7 | $34M | 2.6M | 13.21 | |
| Vaxcyte (PCVX) | 1.7 | $34M | 300k | 114.27 | |
| Revolution Medicines (RVMD) | 1.7 | $34M | 754k | 45.35 | |
| Merus N V (MRUS) | 1.7 | $34M | 682k | 49.96 | |
| Taboola.com Ord Shs (TBLA) | 1.7 | $34M | 10M | 3.36 | |
| Longboard Pharmaceuticals In (LBPH) | 1.5 | $30M | 903k | 33.33 | |
| Xenon Pharmaceuticals (XENE) | 1.5 | $29M | 744k | 39.37 | |
| Cytokinetics Com New (CYTK) | 1.4 | $28M | 526k | 52.80 | |
| Kura Oncology (KURA) | 1.3 | $26M | 1.3M | 19.54 | |
| Arcus Biosciences Incorporated (RCUS) | 1.2 | $25M | 1.6M | 15.29 | |
| Denali Therapeutics (DNLI) | 1.2 | $24M | 834k | 29.13 | |
| Erasca (ERAS) | 1.2 | $24M | 8.9M | 2.73 | |
| Cullinan Oncology (CGEM) | 1.0 | $20M | 1.2M | 16.74 | |
| Tango Therapeutics (TNGX) | 1.0 | $20M | 2.6M | 7.70 | |
| Solid Biosciences Com New (SLDB) | 1.0 | $19M | 2.7M | 6.97 | |
| Prothena Corporation SHS (PRTA) | 0.9 | $18M | 1.1M | 16.73 | |
| NewAmsterdam Pharma Company NV Ordinary Shares (NAMS) | 0.8 | $15M | 921k | 16.60 | |
| Biohaven (BHVN) | 0.7 | $14M | 284k | 49.97 | |
| Korro Bio (KRRO) | 0.7 | $14M | 419k | 33.42 | |
| Applied Therapeutics (APLT) | 0.7 | $14M | 1.6M | 8.50 | |
| Gossamer Bio Call Option (GOSS) | 0.7 | $13M | 14M | 0.99 | |
| Instil Bio Com New (TIL) | 0.6 | $13M | 192k | 67.32 | |
| Edgewise Therapeutics (EWTX) | 0.5 | $11M | 404k | 26.69 | |
| Iovance Biotherapeutics (IOVA) | 0.5 | $10M | 1.1M | 9.39 | |
| Oric Pharmaceuticals (ORIC) | 0.5 | $10M | 1.0M | 10.25 | |
| Ionis Pharmaceuticals (IONS) | 0.5 | $10M | 250k | 40.06 | |
| Taysha Gene Therapies Com Shs (TSHA) | 0.5 | $9.8M | 4.9M | 2.01 | |
| Microsoft Corporation (MSFT) | 0.5 | $9.5M | 22k | 430.12 | |
| Cartesian Therapeutics Com New (RNAC) | 0.5 | $9.2M | 572k | 16.12 | |
| Acelyrin (SLRN) | 0.4 | $8.5M | 1.7M | 4.93 | |
| Phathom Pharmaceuticals (PHAT) | 0.4 | $8.3M | 461k | 18.08 | |
| Seer Com Cl A (SEER) | 0.4 | $7.9M | 4.0M | 1.97 | |
| Rapport Therapeutics (RAPP) | 0.4 | $7.9M | 384k | 20.48 | |
| Neurogene (NGNE) | 0.4 | $7.4M | 176k | 41.96 | |
| Generation Bio (GBIO) | 0.4 | $7.4M | 3.0M | 2.47 | |
| IHS Holding Ord Shs (IHS) | 0.4 | $7.0M | 2.4M | 2.99 | |
| CrowdStrike Holdings Cl A (CRWD) | 0.4 | $7.0M | 25k | 280.47 | |
| Vigil Neuroscience (VIGL) | 0.3 | $6.8M | 2.0M | 3.40 | |
| Foghorn Therapeutics (FHTX) | 0.3 | $6.7M | 721k | 9.31 | |
| Servicenow (NOW) | 0.3 | $6.7M | 7.5k | 894.39 | |
| Amazon (AMZN) | 0.3 | $6.5M | 35k | 186.33 | |
| Bioage Labs | 0.3 | $6.2M | 300k | 20.80 | |
| NVIDIA Corporation (NVDA) | 0.3 | $5.9M | 49k | 121.43 | |
| Syros Pharmaceuticals Com New (SYRS) | 0.3 | $5.6M | 2.6M | 2.15 | |
| Novocure Ord Shs (NVCR) | 0.3 | $5.5M | 351k | 15.63 | |
| Lexeo Therapeutics (LXEO) | 0.3 | $5.5M | 603k | 9.04 | |
| PDD Holdings Sponsored Ads (PDD) | 0.3 | $5.4M | 40k | 134.81 | |
| Allovir (ALVR) | 0.3 | $5.3M | 6.6M | 0.81 | |
| Black Diamond Therapeutics (BDTX) | 0.2 | $4.6M | 1.0M | 4.35 | |
| Alto Neuroscience Com Shs (ANRO) | 0.2 | $4.5M | 391k | 11.44 | |
| Dynatrace Com New (DT) | 0.2 | $4.4M | 83k | 53.47 | |
| Ionq Inc Pipe (IONQ) | 0.2 | $4.4M | 500k | 8.74 | |
| Taiwan Semiconductor Manufacturing Sponsored Ads (TSM) | 0.2 | $4.3M | 25k | 173.67 | |
| Agenus Com New (AGEN) | 0.2 | $4.2M | 775k | 5.48 | |
| Datadog Cl A Com (DDOG) | 0.2 | $3.8M | 33k | 115.06 | |
| ADC Therapeutics SA SHS (ADCT) | 0.2 | $3.7M | 1.2M | 3.15 | |
| Sea Sponsored Ads (SE) | 0.2 | $3.5M | 38k | 94.28 | |
| Ovid Therapeutics (OVID) | 0.2 | $3.4M | 2.9M | 1.18 | |
| Paypal Holdings Call Option (PYPL) | 0.2 | $3.2M | 41k | 78.03 | |
| Regenxbio Inc equity us cm (RGNX) | 0.1 | $3.0M | 284k | 10.49 | |
| New Oriental Education & Technology Group Spon Adr (EDU) | 0.1 | $2.9M | 39k | 75.84 | |
| Qualcomm (QCOM) | 0.1 | $2.6M | 15k | 170.05 | |
| HOOKIPA Pharma Com New (HOOK) | 0.1 | $2.4M | 567k | 4.30 | |
| Tourmaline Bio (TRML) | 0.1 | $2.4M | 91k | 25.71 | |
| Sagimet Biosciences Com Ser A (SGMT) | 0.1 | $2.0M | 725k | 2.77 | |
| Procore Technologies (PCOR) | 0.1 | $2.0M | 32k | 61.72 | |
| Ke Holdings Sponsored Ads (BEKE) | 0.1 | $2.0M | 100k | 19.91 | |
| Visa Com Cl A (V) | 0.1 | $1.9M | 7.0k | 274.95 | |
| Gritstone Oncology Ord (GRTS) | 0.1 | $1.9M | 3.3M | 0.58 | |
| Alphabet Cap Stk Cl A (GOOGL) | 0.1 | $1.8M | 11k | 165.83 | |
| Occidental Petroleum Corporation (OXY) | 0.1 | $1.8M | 35k | 51.54 | |
| Jfrog Ord Shs (FROG) | 0.1 | $1.8M | 61k | 29.04 | |
| Omega Therapeutics Common Stock (OMGA) | 0.1 | $1.6M | 1.3M | 1.22 | |
| Natera (NTRA) | 0.1 | $1.6M | 13k | 126.95 | |
| Palo Alto Networks (PANW) | 0.1 | $1.5M | 4.5k | 341.80 | |
| Elastic NV Ord Shs (ESTC) | 0.0 | $998k | 13k | 76.76 | |
| Intel Corporation (INTC) | 0.0 | $938k | 40k | 23.46 | |
| Meta Platforms Cl A (META) | 0.0 | $859k | 1.5k | 572.44 | |
| Kronos Bio (KRON) | 0.0 | $843k | 843k | 1.00 | |
| Terns Pharmaceuticals (TERN) | 0.0 | $834k | 100k | 8.34 | |
| Rubrik Cl A (RBRK) | 0.0 | $804k | 25k | 32.15 | |
| Achilles Therapeutics Sponsored Ads (ACHL) | 0.0 | $771k | 755k | 1.02 | |
| Dollar Tree (DLTR) | 0.0 | $703k | 10k | 70.32 | |
| Nu Holdings Ord Shs Cl A (NU) | 0.0 | $683k | 50k | 13.65 | |
| Adobe Systems Incorporated (ADBE) | 0.0 | $518k | 1.0k | 517.78 | |
| Ironwood Pharmaceuticals Com Cl A (IRWD) | 0.0 | $455k | 111k | 4.12 | |
| Kanzhun Sponsored Ads (BZ) | 0.0 | $434k | 25k | 17.36 | |
| Remitly Global (RELY) | 0.0 | $335k | 25k | 13.39 | |
| Glycomimetics (GLYC) | 0.0 | $332k | 2.0M | 0.17 | |
| Cyclerion Therapeutics (CYCN) | 0.0 | $301k | 116k | 2.59 | |
| Caribou Biosciences (CRBU) | 0.0 | $207k | 105k | 1.96 | |
| Perception Capital Corp III *w Exp 99/99/999 Call Option (PFTAW) | 0.0 | $3.8k | 127k | 0.03 |
