Soleus Capital Management as of Dec. 31, 2025
Portfolio Holdings for Soleus Capital Management
Soleus Capital Management holds 95 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Spdr Series Trust State Street Spd Put Option (XBI) | 13.0 | $354M | 2.9M | 121.93 | |
| Krystal Biotech (KRYS) | 8.6 | $232M | 941k | 246.54 | |
| Celcuity (CELC) | 6.7 | $180M | 1.8M | 99.74 | |
| Novocure Ord Shs (NVCR) | 4.1 | $110M | 8.5M | 12.93 | |
| Praxis Precision Medicines I Com New (PRAX) | 3.9 | $107M | 363k | 294.74 | |
| Tg Therapeutics (TGTX) | 3.5 | $94M | 3.1M | 29.81 | |
| Dex (DXCM) | 3.2 | $86M | 1.3M | 66.37 | |
| BioMarin Pharmaceutical (BMRN) | 2.9 | $78M | 1.3M | 59.43 | |
| Globus Med Cl A (GMED) | 2.9 | $77M | 887k | 87.31 | |
| Beta Bionics (BBNX) | 2.8 | $77M | 2.5M | 30.47 | |
| Amicus Therapeutics (FOLD) | 2.7 | $74M | 5.2M | 14.24 | |
| Twist Bioscience Corp (TWST) | 2.2 | $59M | 1.9M | 31.72 | |
| Organogenesis Hldgs (ORGO) | 1.9 | $52M | 10M | 5.18 | |
| Syndax Pharmaceuticals (SNDX) | 1.7 | $47M | 2.2M | 21.01 | |
| Mirum Pharmaceuticals (MIRM) | 1.7 | $45M | 574k | 78.99 | |
| Insulet Corporation (PODD) | 1.6 | $43M | 150k | 284.24 | |
| Neuropace (NPCE) | 1.5 | $42M | 2.7M | 15.44 | |
| Axogen (AXGN) | 1.5 | $40M | 1.2M | 32.73 | |
| Biosante Pharmaceuticals (ANIP) | 1.4 | $38M | 486k | 78.94 | |
| Alkermes SHS (ALKS) | 1.4 | $37M | 1.3M | 27.98 | |
| Livanova SHS (LIVN) | 1.3 | $35M | 568k | 61.53 | |
| GSK Sponsored Adr (GSK) | 1.2 | $31M | 639k | 49.04 | |
| Geron Corporation (GERN) | 1.1 | $31M | 23M | 1.32 | |
| United Therapeutics Corporation (UTHR) | 1.1 | $29M | 60k | 487.25 | |
| Immunovant (IMVT) | 1.0 | $28M | 1.1M | 25.42 | |
| Vaxcyte (PCVX) | 1.0 | $28M | 609k | 46.14 | |
| Alnylam Pharmaceuticals (ALNY) | 1.0 | $28M | 70k | 397.65 | |
| Inspire Med Sys (INSP) | 1.0 | $28M | 299k | 92.23 | |
| Vericel (VCEL) | 1.0 | $28M | 764k | 36.01 | |
| Argenx Se Sponsored Adr (ARGX) | 1.0 | $27M | 32k | 840.95 | |
| Rapt Therapeutics Com New (RAPT) | 1.0 | $26M | 764k | 33.87 | |
| Neurocrine Biosciences (NBIX) | 0.9 | $25M | 176k | 141.83 | |
| Kiniksa Pharmaceuticals Intl Ord Shs Cl A (KNSA) | 0.9 | $24M | 587k | 41.25 | |
| Edap Tms S A Sponsored Adr (EDAP) | 0.9 | $24M | 7.3M | 3.29 | |
| Teleflex Incorporated (TFX) | 0.9 | $23M | 190k | 122.04 | |
| Nurix Therapeutics (NRIX) | 0.9 | $23M | 1.2M | 18.97 | |
| Edgewise Therapeutics (EWTX) | 0.8 | $23M | 910k | 24.82 | |
| Inhibikase Therapeutics Com New (IKT) | 0.8 | $22M | 11M | 2.05 | |
| Pharvaris N V (PHVS) | 0.7 | $20M | 702k | 27.75 | |
| Adagio Therapeutics (IVVD) | 0.7 | $19M | 7.7M | 2.47 | |
| Capricor Therapeutics Com New (CAPR) | 0.7 | $19M | 646k | 28.86 | |
| Tenet Healthcare Corp Com New (THC) | 0.7 | $18M | 93k | 198.72 | |
| Arcus Biosciences Incorporated (RCUS) | 0.6 | $17M | 712k | 23.83 | |
| Enliven Therapeutics (ELVN) | 0.6 | $16M | 1.0M | 15.40 | |
| Mbx Biosciences (MBX) | 0.5 | $13M | 409k | 31.54 | |
| Rigel Pharmaceuticals (RIGL) | 0.5 | $13M | 300k | 42.83 | |
| Jade Biosciences Com New (JBIO) | 0.5 | $12M | 797k | 15.43 | |
| Trevi Therapeutics (TRVI) | 0.4 | $11M | 900k | 12.52 | |
| Sionna Therapeutics (SION) | 0.4 | $11M | 269k | 41.14 | |
| Septerna (SEPN) | 0.4 | $11M | 383k | 27.88 | |
| Orthopediatrics Corp. (KIDS) | 0.3 | $9.3M | 525k | 17.76 | |
| Terns Pharmaceuticals (TERN) | 0.3 | $8.6M | 213k | 40.40 | |
| Cidara Therapeutics Com New (CDTX) | 0.3 | $8.6M | 39k | 220.89 | |
| Insmed Com Par $.01 (INSM) | 0.3 | $8.4M | 49k | 174.04 | |
| Cerus Corporation (CERS) | 0.3 | $8.2M | 4.0M | 2.06 | |
| Erasca (ERAS) | 0.3 | $8.0M | 2.2M | 3.72 | |
| Avalo Therapeutics Com New (AVTX) | 0.3 | $8.0M | 442k | 18.16 | |
| C4 Therapeutics Com Stk (CCCC) | 0.3 | $7.3M | 3.8M | 1.91 | |
| Evolus (EOLS) | 0.3 | $7.1M | 1.1M | 6.65 | |
| Cg Oncology (CGON) | 0.3 | $7.1M | 170k | 41.52 | |
| Anaptysbio Inc Common (ANAB) | 0.2 | $6.5M | 135k | 48.48 | |
| Belite Bio Sponsored Ads (BLTE) | 0.2 | $6.5M | 40k | 159.96 | |
| Structure Therapeutics Sponsored Ads (GPCR) | 0.2 | $6.3M | 90k | 69.55 | |
| Abivax Sa Sponsored Ads (ABVX) | 0.2 | $6.1M | 45k | 134.85 | |
| Oruka Therapeutics (ORKA) | 0.2 | $5.8M | 190k | 30.31 | |
| Moonlake Immunotherapeutics Class A Ord (MLTX) | 0.2 | $5.3M | 400k | 13.18 | |
| Neogenomics Com New (NEO) | 0.2 | $5.0M | 428k | 11.76 | |
| Natera (NTRA) | 0.2 | $4.6M | 20k | 229.09 | |
| Calcimedica Com New (CALC) | 0.2 | $4.5M | 684k | 6.59 | |
| Pulmonx Corp (LUNG) | 0.2 | $4.5M | 2.0M | 2.21 | |
| Cogent Biosciences (COGT) | 0.2 | $4.3M | 120k | 35.52 | |
| Indivior Ord | 0.1 | $3.6M | 100k | 35.88 | |
| Urogen Pharma (URGN) | 0.1 | $3.5M | 150k | 23.42 | |
| Tyra Biosciences (TYRA) | 0.1 | $3.3M | 125k | 26.29 | |
| Karyopharm Therapeutics Com New (KPTI) | 0.1 | $3.2M | 440k | 7.36 | |
| Zymeworks Del (ZYME) | 0.1 | $2.6M | 100k | 26.33 | |
| Viking Therapeutics (VKTX) | 0.1 | $2.5M | 70k | 35.18 | |
| Quidel Corp (QDEL) | 0.1 | $2.1M | 75k | 28.56 | |
| Inspiremd (NSPR) | 0.1 | $2.0M | 1.2M | 1.78 | |
| Inhibrx Biosciences (INBX) | 0.1 | $2.0M | 25k | 79.00 | |
| Arcellx Common Stock (ACLX) | 0.1 | $2.0M | 30k | 65.20 | |
| Olema Pharmaceuticals (OLMA) | 0.1 | $1.7M | 70k | 25.00 | |
| Bicara Therapeutics (BCAX) | 0.1 | $1.7M | 100k | 16.83 | |
| Kodiak Sciences (KOD) | 0.1 | $1.7M | 60k | 27.96 | |
| Grail (GRAL) | 0.0 | $942k | 11k | 85.59 | |
| Fractyl Health (GUTS) | 0.0 | $880k | 400k | 2.20 | |
| Staar Surgical Com Par $0.01 (STAA) | 0.0 | $577k | 25k | 23.09 | |
| Veracyte (VCYT) | 0.0 | $421k | 10k | 42.10 | |
| Jasper Therapeutics Com New (JSPR) | 0.0 | $366k | 200k | 1.83 | |
| Quoin Pharmaceuticals Sponsored Ads (QNRX) | 0.0 | $361k | 25k | 14.43 | |
| Madrigal Pharmaceuticals (MDGL) | 0.0 | $291k | 500.00 | 582.34 | |
| Lb Pharmaceuticals Com Shs (LBRX) | 0.0 | $223k | 10k | 22.26 | |
| Dyne Therapeutics (DYN) | 0.0 | $196k | 10k | 19.56 | |
| Delcath Sys Com New (DCTH) | 0.0 | $101k | 10k | 10.10 | |
| Tango Therapeutics (TNGX) | 0.0 | $89k | 10k | 8.86 |
