Hambrecht & Quist Capital Management

Tekla Capital Management as of Dec. 31, 2020

Portfolio Holdings for Tekla Capital Management

Tekla Capital Management holds 200 positions in its portfolio as reported in the December 2020 quarterly 13F filing

Company (Ticker) Portfolio Weight Valued At Change in Shares Share Count Share Price
Amgen Common (AMGN) 3.4 $96M 417k 229.92
Illumina Common (ILMN) 3.3 $95M 258k 370.00
Regeneron Pharmaceuticals Common (REGN) 3.0 $87M 179k 483.11
Johnson & Johnson Common (JNJ) 3.0 $86M 547k 157.38
Gilead Sciences Common (GILD) 2.9 $82M 1.4M 58.26
Alexion Pharmaceuticals Common 2.8 $78M 502k 156.24
Unitedhealth Group Incorporated Common (UNH) 2.7 $77M 219k 350.68
Vertex Pharmaceuticals Incorporated Common (VRTX) 2.5 $72M 305k 236.34
AbbVie Common (ABBV) 2.3 $66M 620k 107.15
Medtronic Shares (MDT) 2.2 $63M 535k 117.14
Bristol Myers Squibb Company Common (BMY) 2.2 $61M 990k 62.03
Biogen Common (BIIB) 2.1 $60M 247k 244.86
Thermo Fisher Scientific Common (TMO) 2.1 $59M 128k 465.78
Seagen Common 1.8 $51M 294k 175.14
Danaher Corporation Common (DHR) 1.7 $49M 220k 222.14
Abbott Laboratories Common (ABT) 1.7 $47M 431k 109.49
Merck & Co Common (MRK) 1.6 $46M 561k 81.80
Eli Lilly and Company Common (LLY) 1.4 $40M 238k 168.84
Stryker Corporation Common (SYK) 1.3 $38M 153k 245.04
Sarepta Therapeutics Common (SRPT) 1.2 $35M 207k 170.49
Horizon Therapeutics Shares 1.2 $34M 465k 73.15
Humana Common (HUM) 1.2 $34M 83k 410.27
Zimmer Biomet Holdings Common (ZBH) 1.2 $33M 214k 154.09
Becton, Dickinson and Company Common (BDX) 1.2 $33M 132k 250.22
HCA Healthcare Common (HCA) 1.0 $29M 175k 164.46
Cigna Corporation Common (CI) 1.0 $28M 136k 208.18
Neurocrine Biosciences Common (NBIX) 1.0 $28M 294k 95.85
ResMed Common (RMD) 1.0 $28M 132k 212.56
DexCom Common (DXCM) 1.0 $28M 75k 369.72
Waters Corporation Common (WAT) 1.0 $27M 110k 247.42
Pfizer Common (PFE) 0.9 $26M 705k 36.81
Moderna Common (MRNA) 0.9 $26M 248k 104.47
Exelixis Common (EXEL) 0.9 $25M 1.3M 20.07
BioMarin Pharmaceutical Common (BMRN) 0.9 $24M 278k 87.69
Edwards Lifesciences Corporation Common (EW) 0.8 $24M 265k 91.23
Steris Shares (STE) 0.8 $24M 127k 189.54
Alnylam Pharmaceuticals Common (ALNY) 0.8 $23M 175k 129.97
McKesson Corp. Common (MCK) 0.8 $23M 130k 173.92
PRA Health Sciences Common 0.8 $22M 176k 125.44
Arena Pharmaceuticals Common 0.7 $19M 253k 76.83
Dentsply Sirona Common (XRAY) 0.7 $19M 366k 52.36
Mirati Therapeutics Common 0.6 $18M 84k 219.64
Allakos Common 0.6 $18M 131k 140.00
Argenx SE Sponsored ADR (ARGX) 0.6 $18M 62k 294.10
ACADIA Pharmaceuticals Common (ACAD) 0.6 $18M 332k 53.46
Intuitive Surgical Common (ISRG) 0.6 $17M 21k 818.09
IDEXX Laboratories Common (IDXX) 0.6 $17M 35k 499.86
AstraZeneca Sponsored ADR (AZN) 0.6 $17M 344k 49.99
Adaptive Biotechnologies Corporation Common (ADPT) 0.6 $17M 286k 59.13
Bio-Techne Corporation Common (TECH) 0.6 $16M 52k 317.56
Ascendis Pharma A/S Sponsored ADR (ASND) 0.6 $16M 96k 166.78
Sutro Biopharma Common (STRO) 0.5 $15M 703k 21.71
NovoCure Ordinary Shares (NVCR) 0.5 $15M 88k 173.04
Guardant Health Common (GH) 0.5 $15M 118k 128.88
Fate Therapeutics Common (FATE) 0.5 $15M 166k 90.93
CVS Health Corporation Common (CVS) 0.5 $15M 220k 68.30
Turning Point Therapeutics Common 0.5 $15M 119k 121.85
Blueprint Medicines Corporation Common (BPMC) 0.5 $14M 123k 112.15
Novartis Sponsored ADR (NVS) 0.5 $14M 145k 94.43
IQVIA Holdings Common (IQV) 0.5 $14M 76k 179.17
Ultragenyx Pharmaceutical Common (RARE) 0.5 $14M 98k 138.43
Syneos Health Class A 0.5 $13M 195k 68.13
Sage Therapeutics Common (SAGE) 0.5 $13M 152k 86.51
Laboratory Corporation of America Holdings Sponsored ADR 0.5 $13M 65k 203.55
Welltower Common (WELL) 0.5 $13M 203k 64.62
Quest Diagnostics Incorporated Common (DGX) 0.5 $13M 110k 119.17
Iovance Biotherapeutics Common (IOVA) 0.4 $13M 271k 46.40
Apellis Pharmaceuticals Common (APLS) 0.4 $12M 216k 57.20
Trillium Therapeutics Common 0.4 $12M 818k 14.71
Anthem Common (ELV) 0.4 $12M 37k 321.09
CRISPR Therapeutics Namen AKT (CRSP) 0.4 $12M 76k 153.11
Intra-Cellular Therapies Common (ITCI) 0.4 $12M 366k 31.80
Teladoc Health Common (TDOC) 0.4 $11M 57k 199.96
Mettler-Toledo International Common (MTD) 0.4 $11M 9.8k 1139.69
Jazz Pharmaceuticals Shares (JAZZ) 0.4 $11M 68k 165.06
Omega Healthcare Investors Common (OHI) 0.4 $11M 306k 36.32
Ionis Pharmaceuticals Common (IONS) 0.4 $11M 193k 56.54
Galera Therapeutics Common (GRTX) 0.4 $11M 1.0M 10.23
Genmab A/S Sponsored ADS (GMAB) 0.4 $11M 259k 40.66
Ventas Common (VTR) 0.4 $10M 208k 49.04
Arrowhead Pharmaceuticals Common (ARWR) 0.4 $10M 133k 76.73
United Therapeutics Corporation Class B (UTHR) 0.3 $9.6M 64k 151.80
Amicus Therapeutics Common (FOLD) 0.3 $9.4M 406k 23.09
Zoetis Class A (ZTS) 0.3 $9.4M 57k 165.50
Medical Properties Trust Common (MPW) 0.3 $9.0M 412k 21.79
ChemoCentryx Common 0.3 $8.9M 144k 61.92
Kura Oncology Common (KURA) 0.3 $8.9M 274k 32.66
Sabra Health Care REIT Common (SBRA) 0.3 $8.9M 511k 17.37
Boston Scientific Corporation Common (BSX) 0.3 $8.8M 246k 35.95
Physicians Realty Trust Common 0.3 $8.8M 496k 17.80
Karuna Therapeutics Common 0.3 $8.7M 85k 101.59
Novavax Common (NVAX) 0.3 $8.5M 77k 111.51
Molina Healthcare Common (MOH) 0.3 $8.5M 40k 212.68
Exact Sciences Corporation Common (EXAS) 0.3 $8.4M 64k 132.48
Incyte Corporation Common (INCY) 0.3 $8.1M 93k 86.97
Theravance Biopharma Common (TBPH) 0.3 $8.1M 456k 17.77
BeiGene Sponsored ADR (ONC) 0.3 $7.3M 28k 258.38
FibroGen Common 0.3 $7.2M 194k 37.09
Owens & Minor Common (OMI) 0.3 $7.2M 266k 27.05
LTC Properties Common (LTC) 0.2 $7.1M 182k 38.91
Teva Pharmaceutical Industries Sponsored ADR (TEVA) 0.2 $7.0M 730k 9.65
Charles River Laboratories International Common (CRL) 0.2 $7.0M 28k 249.88
TG Therapeutics Common (TGTX) 0.2 $6.9M 133k 52.02
Xencor Common (XNCR) 0.2 $6.5M 148k 43.63
Arvinas Common (ARVN) 0.2 $6.2M 74k 84.93
Agilent Technologies Common (A) 0.2 $6.2M 53k 118.50
Teleflex Incorporated Common (TFX) 0.2 $6.2M 15k 411.57
Denali Therapeutics Common (DNLI) 0.2 $6.1M 72k 83.77
Revance Therapeutics Common 0.2 $6.1M 214k 28.34
Cogent Biosciences Common (COGT) 0.2 $6.0M 538k 11.23
Atreca Class A Common (BCEL) 0.2 $5.7M 352k 16.15
Amedisys Common (AMED) 0.2 $5.7M 19k 293.32
Scholar Rock Holding Corporation Common (SRRK) 0.2 $5.6M 116k 48.53
Align Technology Common (ALGN) 0.2 $5.4M 10k 534.41
PerkinElmer Common (RVTY) 0.2 $5.3M 37k 143.50
Verona Pharma Sponsored ADR (VRNA) 0.2 $5.3M 752k 7.00
Forma Therapeutics Holdings Shares 0.2 $5.2M 150k 34.90
Zai Lab Adr (ZLAB) 0.2 $5.1M 38k 135.33
Centene Corporation Common (CNC) 0.2 $5.1M 84k 60.03
Reata Pharmaceuticals Class A 0.2 $4.7M 38k 123.63
Healthpeak Properties Common (DOC) 0.2 $4.5M 150k 30.23
Novo Nordisk A/S Sponsored ADR (NVO) 0.2 $4.5M 65k 69.85
uniQure Shares (QURE) 0.2 $4.5M 125k 36.13
Addus HomeCare Corporation Common (ADUS) 0.2 $4.4M 38k 117.08
Smith & Nephew Shares (SNN) 0.1 $4.2M 100k 42.17
Aurinia Pharmaceuticals Common (AUPH) 0.1 $4.2M 301k 13.83
Amarin Corporation Sponsored ADR 0.1 $4.2M 850k 4.89
Praxis Precision Medicines Common 0.1 $4.1M 75k 55.03
Axonics Modulation Technologies Common (AXNX) 0.1 $4.0M 81k 49.93
Sanofi Sponsored ADR (SNY) 0.1 $4.0M 82k 48.59
Ardelyx Common (ARDX) 0.1 $3.9M 608k 6.47
Takeda Pharmaceutical Company Sponsored ADS (TAK) 0.1 $3.8M 210k 18.20
Endo International Shares 0.1 $3.8M 532k 7.18
Y-mAbs Therapeutics Common 0.1 $3.8M 77k 49.51
Pieris Pharmaceuticals Common 0.1 $3.6M 1.4M 2.50
Abiomed Common 0.1 $3.5M 11k 324.18
Deciphera Pharmaceuticals Common 0.1 $3.5M 61k 57.06
Alkermes Shares (ALKS) 0.1 $3.4M 170k 19.95
Tenet Healthcare Corporation Common (THC) 0.1 $3.3M 83k 39.93
Insmed Incorporated Common (INSM) 0.1 $3.3M 98k 33.29
Koninklijke Philips NY Reg Sh (PHG) 0.1 $3.1M 57k 54.17
Healthcare Realty Trust Incorporated Common 0.1 $3.1M 104k 29.60
Nektar Therapeutics Common 0.1 $3.1M 180k 17.00
Kadmon Holdings Common 0.1 $3.0M 714k 4.15
Heron Therapeutics Common (HRTX) 0.1 $2.8M 131k 21.16
Helix Acquisition Corp. Class A Common 0.1 $2.7M 250k 10.83
Zymeworks Common 0.1 $2.6M 56k 47.27
Eidos Therapeutics Common 0.1 $2.6M 20k 131.60
Medpace Holdings Common (MEDP) 0.1 $2.6M 19k 139.21
Axsome Therapeutics Common (AXSM) 0.1 $2.6M 32k 81.48
Hologic Common (HOLX) 0.1 $2.4M 33k 72.84
MorphoSys Sponsored ADS (MOR) 0.1 $2.3M 82k 28.34
Inogen Common (INGN) 0.1 $2.3M 51k 44.68
Perrigo Company Shares (PRGO) 0.1 $2.3M 51k 44.73
Global Medical REIT Common 0.1 $2.3M 175k 13.06
Bausch Health Companies Common (BHC) 0.1 $2.1M 101k 20.80
NuCana Sponsored ADR 0.1 $2.1M 461k 4.49
Alcon Ordinary Shares (ALC) 0.1 $2.1M 31k 65.97
Molecular Templates Common 0.1 $2.1M 220k 9.39
Healthcare Trust of America Common 0.1 $1.9M 71k 27.54
Intercept Pharmaceuticals Common 0.1 $1.9M 77k 24.71
Zogenix Common 0.1 $1.8M 89k 19.99
Harpoon Therapeutics Common 0.1 $1.8M 106k 16.61
Milestone Pharmaceuticals Common (MIST) 0.1 $1.7M 254k 6.70
Gritstone Oncology Common (GRTSQ) 0.1 $1.7M 419k 3.94
Avadel Pharmaceuticals Sponsored ADR 0.1 $1.6M 234k 6.68
Affimed Common 0.1 $1.6M 268k 5.82
Magenta Therapeutics Common 0.1 $1.5M 192k 7.84
Dicerna Pharmaceuticals Common 0.1 $1.5M 68k 22.02
Madrigal Pharmaceuticals Common (MDGL) 0.1 $1.5M 13k 111.17
Diversified Healthcare Trust Common (DHC) 0.1 $1.5M 358k 4.12
New Senior Investment Group Common 0.0 $1.3M 256k 5.18
Allogene Therapeutics Common (ALLO) 0.0 $1.2M 48k 25.24
Health Care Select Sector SPDR Fund SBI Healthcare (XLV) 0.0 $1.1M 10k 113.48
ImmunoGen Common 0.0 $1.1M 168k 6.45
Esperion Therapeutics Common (ESPR) 0.0 $1.1M 42k 26.00
Karyopharm Therapeutics Common 0.0 $1.0M 66k 15.48
Bristol Myers Squibb Company Right 0.0 $1.0M 1.5M 0.69
Regenxbio Common (RGNX) 0.0 $984k 22k 45.35
Aerie Pharmaceuticals Common 0.0 $901k 67k 13.51
AC Immune SA Shares (ACIU) 0.0 $888k 172k 5.17
Community Health Systems Common (CYH) 0.0 $875k 118k 7.43
Grifols Sponsored ADR (GRFS) 0.0 $874k 47k 18.45
Ovid Therapeutics Sponsored ADR (OVID) 0.0 $861k 373k 2.31
VYNE Therapeutics Common 0.0 $856k 542k 1.58
Universal Health Realty Income Trust Shares (UHT) 0.0 $724k 11k 64.31
Community Healthcare Trust Incorporated Common (CHCT) 0.0 $702k 15k 47.11
National Health Investors Common (NHI) 0.0 $694k 10k 69.14
Assertio Holdings Common 0.0 $587k 1.6M 0.36
Corbus Pharmaceuticals Holdings Common 0.0 $517k 414k 1.25
CymaBay Therapeutics Common 0.0 $506k 88k 5.74
Clearside Biomedical Common (CLSD) 0.0 $453k 165k 2.74
Spectrum Pharmaceuticals Common 0.0 $391k 115k 3.41
Cellectis Sponsored ADR (CLLS) 0.0 $324k 12k 27.10
Viatris Common (VTRS) 0.0 $251k 13k 18.73
Five Star Senior Living Common 0.0 $167k 24k 6.89
ARCA biopharma Common (ABIO) 0.0 $130k 33k 4.00
Celldex Therapeutics Common (CLDX) 0.0 $124k 7.1k 17.58
Bellicum Pharmaceuticals Common 0.0 $21k 6.0k 3.50
Tetraphase Pharmaceuticals Common 0.0 $9.0k 43k 0.21