Paradigm Biocapital Advisors
Latest statistics and disclosures from Paradigm Biocapital Advisors's latest quarterly 13F-HR filing:
- Top 5 stock holdings are ACLX, RVMD, NUVL, PCVX, EWTX, and represent 48.35% of Paradigm Biocapital Advisors's stock portfolio.
- Added to shares of these 10 stocks: INSM (+$205M), BLTE (+$178M), CNTA (+$142M), CYTK (+$98M), TNGX (+$84M), MAZE (+$82M), TYRA (+$79M), TERN (+$74M), MIRM (+$58M), PCVX (+$42M).
- Started 10 new stock positions in GPCR, Veradermics, TNGX, CYTK, MIRM, MAZE, TYRA, BLTE, INSM, CNTA.
- Reduced shares in these 10 stocks: , CDTX (-$168M), CRNX (-$103M), SRRK (-$90M), ABVX (-$72M), ERAS (-$61M), BBIO (-$52M), URGN (-$50M), OCUL (-$36M), BBOT (-$13M).
- Sold out of its positions in BBIO, CDTX, CRNX, OCUL, XBI.
- Paradigm Biocapital Advisors was a net buyer of stock by $443M.
- Paradigm Biocapital Advisors has $4.9B in assets under management (AUM), dropping by 24.92%.
- Central Index Key (CIK): 0001855655
Tip: Access up to 7 years of quarterly data
Positions held by Paradigm Biocapital Advisors consolidated in one spreadsheet with up to 7 years of data
Download as csvPortfolio Holdings for Paradigm Biocapital Advisors
Paradigm Biocapital Advisors holds 35 positions in its portfolio as reported in the March 2026 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
|---|---|---|---|---|---|---|
| Arcellx Common Stock (ACLX) | 13.5 | $663M | 5.8M | 114.82 |
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| Revolution Medicines (RVMD) | 13.2 | $647M | 6.7M | 97.25 |
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| Nuvalent Inc-a (NUVL) | 11.1 | $546M | 5.3M | 102.45 |
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| Vaxcyte (PCVX) | 5.7 | $279M | +17% | 4.8M | 58.11 |
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| Edgewise Therapeutics (EWTX) | 4.7 | $232M | +12% | 7.4M | 31.50 |
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| Genmab A/s Sponsored Ads (GMAB) | 4.4 | $214M | +13% | 8.0M | 26.83 |
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| Insmed Com Par $.01 (INSM) | 4.2 | $205M | NEW | 1.3M | 163.52 |
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| Tarsus Pharmaceuticals (TARS) | 3.7 | $180M | 2.6M | 70.15 |
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| Belite Bio Sponsored Ads (BLTE) | 3.6 | $178M | NEW | 1.1M | 159.44 |
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| Erasca (ERAS) | 3.4 | $168M | -26% | 10M | 16.18 |
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| Centessa Pharmaceuticals Sponsored Ads (CNTA) | 2.9 | $142M | NEW | 3.6M | 39.72 |
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| Olema Pharmaceuticals (OLMA) | 2.4 | $120M | +6% | 8.0M | 14.91 |
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| Terns Pharmaceuticals (TERN) | 2.4 | $117M | +173% | 2.2M | 52.72 |
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| Oruka Therapeutics (ORKA) | 2.3 | $114M | +35% | 2.3M | 49.05 |
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| Apogee Therapeutics (APGE) | 2.3 | $114M | +20% | 1.3M | 84.17 |
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| Spyre Therapeutics Com New (SYRE) | 2.0 | $99M | +33% | 2.0M | 50.44 |
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| Cytokinetics Com New (CYTK) | 2.0 | $98M | NEW | 1.5M | 65.91 |
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| Abivax Sa Sponsored Ads (ABVX) | 1.8 | $86M | -45% | 773k | 111.35 |
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| Tango Therapeutics (TNGX) | 1.7 | $84M | NEW | 4.0M | 20.92 |
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| Maze Therapeatics (MAZE) | 1.7 | $82M | NEW | 2.7M | 29.85 |
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| Tyra Biosciences (TYRA) | 1.6 | $79M | NEW | 2.1M | 38.30 |
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| Miragen Therapeutics (VRDN) | 1.3 | $62M | +118% | 3.1M | 19.56 |
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| Scholar Rock Hldg Corp (SRRK) | 1.2 | $60M | -59% | 1.2M | 49.16 |
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| Mirum Pharmaceuticals (MIRM) | 1.2 | $58M | NEW | 625k | 92.38 |
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| Eyepoint Com New (EYPT) | 0.8 | $41M | -14% | 3.1M | 12.89 |
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| Lexeo Therapeutics (LXEO) | 0.7 | $36M | +29% | 6.2M | 5.74 |
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| Veradermics Common Stock | 0.7 | $33M | NEW | 525k | 63.15 |
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| Vor Biopharma Com New (VOR) | 0.6 | $31M | 1.8M | 17.84 |
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| Urogen Pharma (URGN) | 0.6 | $31M | -61% | 1.7M | 17.98 |
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| Structure Therapeutics Sponsored Ads (GPCR) | 0.5 | $26M | NEW | 545k | 48.20 |
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| Inventiva Sa Ads (IVA) | 0.5 | $22M | 4.0M | 5.55 |
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| Oric Pharmaceuticals (ORIC) | 0.4 | $22M | -29% | 1.7M | 12.67 |
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| Assembly Biosciences Com New (ASMB) | 0.4 | $19M | 665k | 27.75 |
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| Bridgebio Oncology Therapeut Com New (BBOT) | 0.2 | $7.8M | -61% | 868k | 8.95 |
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| Kalaris Therapeutics (KLRS) | 0.1 | $4.0M | 700k | 5.77 |
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Past Filings by Paradigm Biocapital Advisors
SEC 13F filings are viewable for Paradigm Biocapital Advisors going back to 2021
- Paradigm Biocapital Advisors 2026 Q1 filed May 15, 2026
- Paradigm Biocapital Advisors 2025 Q4 filed Feb. 17, 2026
- Paradigm Biocapital Advisors 2025 Q3 filed Nov. 14, 2025
- Paradigm Biocapital Advisors 2025 Q2 filed Aug. 14, 2025
- Paradigm Biocapital Advisors 2025 Q1 filed May 15, 2025
- Paradigm Biocapital Advisors 2024 Q4 filed Feb. 14, 2025
- Paradigm Biocapital Advisors 2024 Q3 filed Nov. 14, 2024
- Paradigm Biocapital Advisors 2024 Q2 filed Aug. 14, 2024
- Paradigm Biocapital Advisors 2024 Q1 filed May 15, 2024
- Paradigm Biocapital Advisors 2023 Q4 filed Feb. 14, 2024
- Paradigm Biocapital Advisors 2023 Q3 filed Nov. 14, 2023
- Paradigm Biocapital Advisors 2023 Q2 filed Aug. 14, 2023
- Paradigm Biocapital Advisors 2023 Q1 filed May 15, 2023
- Paradigm Biocapital Advisors 2022 Q4 filed Feb. 14, 2023
- Paradigm Biocapital Advisors 2022 Q3 filed Nov. 14, 2022
- Paradigm Biocapital Advisors 2022 Q2 filed Aug. 15, 2022