Paradigm Biocapital Advisors as of Dec. 31, 2025
Portfolio Holdings for Paradigm Biocapital Advisors
Paradigm Biocapital Advisors holds 30 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price |
|---|---|---|---|---|---|
| Nuvalent Inc-a (NUVL) | 13.5 | $530M | 5.3M | 100.59 | |
| Revolution Medicines (RVMD) | 13.5 | $529M | 6.6M | 79.65 | |
| Arcellx Common Stock (ACLX) | 9.5 | $373M | 5.7M | 65.20 | |
| Genmab A/s Sponsored Ads (GMAB) | 5.5 | $217M | 7.0M | 30.80 | |
| Tarsus Pharmaceuticals (TARS) | 5.4 | $210M | 2.6M | 81.88 | |
| Abivax Sa Sponsored Ads (ABVX) | 4.9 | $191M | 1.4M | 134.85 | |
| Olema Pharmaceuticals (OLMA) | 4.8 | $189M | 7.5M | 25.00 | |
| Vaxcyte (PCVX) | 4.8 | $188M | 4.1M | 46.14 | |
| Spdr Series Trust State Street Spd Put Option (XBI) | 4.7 | $183M | 1.5M | 121.93 | |
| Cidara Therapeutics Com New (CDTX) | 4.3 | $168M | 760k | 220.89 | |
| Edgewise Therapeutics (EWTX) | 4.1 | $162M | 6.5M | 24.82 | |
| Scholar Rock Hldg Corp (SRRK) | 3.4 | $135M | 3.1M | 44.05 | |
| Urogen Pharma (URGN) | 2.7 | $105M | 4.5M | 23.42 | |
| Crinetics Pharmaceuticals In (CRNX) | 2.6 | $103M | 2.2M | 46.55 | |
| Apogee Therapeutics (APGE) | 2.2 | $85M | 1.1M | 75.48 | |
| Eyepoint Com New (EYPT) | 1.7 | $67M | 3.7M | 18.27 | |
| Erasca (ERAS) | 1.3 | $53M | 14M | 3.72 | |
| Bridgebio Pharma (BBIO) | 1.3 | $52M | 684k | 76.49 | |
| Oruka Therapeutics (ORKA) | 1.3 | $52M | 1.7M | 30.31 | |
| Spyre Therapeutics Com New (SYRE) | 1.2 | $48M | 1.5M | 32.76 | |
| Lexeo Therapeutics (LXEO) | 1.2 | $47M | 4.8M | 9.93 | |
| Miragen Therapeutics (VRDN) | 1.1 | $45M | 1.4M | 31.12 | |
| Ocular Therapeutix (OCUL) | 0.9 | $36M | 2.9M | 12.14 | |
| Terns Pharmaceuticals (TERN) | 0.8 | $33M | 810k | 40.40 | |
| Bridgebio Oncology Therapeut Com New (BBOT) | 0.7 | $28M | 2.3M | 12.52 | |
| Vor Biopharma Com New (VOR) | 0.6 | $23M | 1.8M | 13.08 | |
| Assembly Biosciences Com New (ASMB) | 0.6 | $23M | 665k | 34.01 | |
| Oric Pharmaceuticals (ORIC) | 0.5 | $20M | 2.4M | 8.18 | |
| Inventiva Sa Ads (IVA) | 0.5 | $19M | 4.0M | 4.65 | |
| Kalaris Therapeutics (KLRS) | 0.2 | $5.9M | 700k | 8.44 |
