RA Capital Management
Latest statistics and disclosures from Ra Capital Management's latest quarterly 13F-HR filing:
- Top 5 stock holdings are ASND, CDTX, RYTM, RNA, PCVX, and represent 49.01% of Ra Capital Management's stock portfolio.
- Added to shares of these 10 stocks: BCRX (+$124M), PRAX (+$110M), RYTM (+$106M), OLMA (+$65M), NUVL (+$64M), EVMN (+$59M), SYRE (+$53M), LXEO (+$50M), VOR (+$45M), CAPR (+$44M).
- Started 22 new stock positions in MDLN, SYRE, RANI, BCRX, CCCC, OLMA, RZLT, PALI, PRAX, PTN. KIDS, HNGE, OVID, ACET, EVMN, CAPR, HCAT, Qiagen Nv, WAY, GRAL, LXEO, BNTC.
- Reduced shares in these 10 stocks: ETNB (-$292M), ACLX (-$115M), CLYM (-$81M), BLTE (-$71M), PCVX (-$57M), DNTH (-$52M), FULC (-$47M), SRRK (-$44M), GPCR (-$43M), MTSR (-$35M).
- Sold out of its positions in Adicet Bio, RCUS, CTMX, ETNB, ELDN, EVH, EXAS, GKOS, LRMR, MTSR. PRME, SRRK, GPCR, SRZN, TNGX, TVTX, IFRX, QURE.
- Ra Capital Management was a net seller of stock by $-17M.
- Ra Capital Management has $9.7B in assets under management (AUM), dropping by 19.87%.
- Central Index Key (CIK): 0001346824
Tip: Access up to 7 years of quarterly data
Positions held by RA Capital Management consolidated in one spreadsheet with up to 7 years of data
Download as csvPortfolio Holdings for Ra Capital Management
Ra Capital Management holds 71 positions in its portfolio as reported in the December 2025 quarterly 13F filing
| Company (Ticker) | Portfolio Weight | Valued At | Change in Shares | Share Count | Share Price | |
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| Ascendis Pharma A/s - SH (ASND) | 22.5 | $2.2B | 10M | 213.24 |
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| Cidara Therapeutics SH (CDTX) | 7.6 | $743M | 3.4M | 220.89 |
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| Rhythm Pharmaceuticals SH (RYTM) | 7.3 | $714M | +17% | 6.7M | 107.04 |
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| Avidity Biosciences SH (RNA) | 6.4 | $623M | 8.6M | 72.13 |
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| Vaxcyte SH (PCVX) | 5.1 | $495M | -10% | 11M | 46.14 |
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| Sionna Therapeutics SH (SION) | 4.2 | $408M | -5% | 9.9M | 41.14 |
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| Newamsterdam Pharma Co Nv SH (NAMS) | 3.4 | $335M | -5% | 9.6M | 35.08 |
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| Tyra Biosciences SH (TYRA) | 3.3 | $321M | 12M | 26.29 |
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| Wave Life Sciences SH (WVE) | 3.2 | $310M | 18M | 17.00 |
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| Mineralys Therapeutics SH (MLYS) | 2.7 | $266M | 7.3M | 36.29 |
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| Edgewise Therapeutics SH (EWTX) | 2.7 | $259M | 10M | 24.82 |
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| Septerna SH (SEPN) | 2.0 | $195M | 7.0M | 27.88 |
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| Nuvalent Inc-a SH (NUVL) | 1.9 | $189M | +50% | 1.9M | 100.59 |
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| Disc Medicine SH (IRON) | 1.6 | $157M | +25% | 2.0M | 79.41 |
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| Janux Therapeutics SH (JANX) | 1.6 | $154M | 11M | 13.80 |
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| Pepgen SH (PEPG) | 1.3 | $131M | 20M | 6.51 |
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| Taysha Gene Therapies SH (TSHA) | 1.3 | $130M | 24M | 5.50 |
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| Ars Pharmaceuticals SH (SPRY) | 1.3 | $127M | 11M | 11.65 |
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| Biocryst Pharmaceuticals SH (BCRX) | 1.3 | $124M | NEW | 16M | 7.80 |
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| Bicara Therapeutics SH (BCAX) | 1.2 | $117M | 7.0M | 16.83 |
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| Praxis Precision Medicines I SH (PRAX) | 1.1 | $110M | NEW | 374k | 294.74 |
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| Gh Research SH (GHRS) | 1.0 | $98M | 7.7M | 12.70 |
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| Geron Corp SH (GERN) | 0.9 | $84M | +5% | 64M | 1.32 |
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| Arcellx SH (ACLX) | 0.8 | $83M | -58% | 1.3M | 65.20 |
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| Vor Biopharma SH (VOR) | 0.7 | $71M | +172% | 5.4M | 13.08 |
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| Belite Bio Inc - SH (BLTE) | 0.7 | $69M | -50% | 433k | 159.96 |
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| Fulcrum Therapeutics SH (FULC) | 0.7 | $69M | -40% | 6.1M | 11.31 |
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| Lenz Therapeutics SH (LENZ) | 0.7 | $67M | 4.2M | 16.00 |
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| Dianthus Therapeutics SH (DNTH) | 0.7 | $66M | -43% | 1.6M | 41.21 |
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| Olema Pharmaceuticals SH (OLMA) | 0.7 | $65M | NEW | 2.6M | 25.00 |
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| Evommune SH (EVMN) | 0.6 | $59M | NEW | 3.5M | 17.12 |
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| Jade Biosciences SH (JBIO) | 0.6 | $57M | +245% | 3.7M | 15.43 |
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| Spyre Therapeutics SH (SYRE) | 0.5 | $53M | NEW | 1.6M | 32.76 |
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| Lexeo Therapeutics SH (LXEO) | 0.5 | $50M | NEW | 5.0M | 9.93 |
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| Lb Pharmaceuticals SH (LBRX) | 0.5 | $49M | +24% | 2.2M | 22.26 |
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| Climb Bio SH (CLYM) | 0.5 | $45M | -64% | 11M | 4.00 |
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| Monopar Therapeutics SH (MNPR) | 0.4 | $44M | +30% | 667k | 65.30 |
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| Capricor Therapeutics SH (CAPR) | 0.4 | $44M | NEW | 1.5M | 28.86 |
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| 4d Molecular Therapeutics In SH (FDMT) | 0.4 | $42M | +23% | 5.7M | 7.50 |
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| Invivyd SH (IVVD) | 0.4 | $42M | 17M | 2.47 |
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| Artiva Biotherapeutics SH (ARTV) | 0.4 | $42M | 9.9M | 4.29 |
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| Grail SH (GRAL) | 0.4 | $37M | NEW | 428k | 85.59 |
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| Assembly Biosciences SH (ASMB) | 0.4 | $35M | 1.0M | 34.01 |
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| Solid Biosciences SH (SLDB) | 0.3 | $33M | 5.8M | 5.64 |
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| Acumen Pharmaceuticals SH (ABOS) | 0.3 | $32M | 15M | 2.11 |
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| Benitec Biopharma SH (BNTC) | 0.3 | $25M | NEW | 1.9M | 13.47 |
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| Contineum Therapeutics Inc-a SH (CTNM) | 0.3 | $25M | +2% | 2.2M | 11.43 |
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| Rezolute SH (RZLT) | 0.2 | $22M | NEW | 9.2M | 2.36 |
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| Acrivon Therapeutics SH (ACRV) | 0.2 | $20M | 8.3M | 2.41 |
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| Nkarta SH (NKTX) | 0.2 | $20M | 11M | 1.85 |
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| Ovid Therapeutics SH (OVID) | 0.2 | $18M | NEW | 11M | 1.63 |
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| Palisade Bio SH (PALI) | 0.2 | $17M | NEW | 7.1M | 2.35 |
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| Sab Biotherapeutics SH (SABS) | 0.2 | $17M | 4.4M | 3.74 |
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| C4 Therapeutics SH (CCCC) | 0.2 | $15M | NEW | 8.0M | 1.91 |
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| Medline Inc-cl A SH (MDLN) | 0.1 | $14M | NEW | 335k | 42.00 |
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| Design Therapeutics SH (DSGN) | 0.1 | $14M | +207% | 1.5M | 9.38 |
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| Inspire Medical Systems SH (INSP) | 0.1 | $13M | +23% | 142k | 92.23 |
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| Avalo Therapeutics SH (AVTX) | 0.1 | $12M | 663k | 18.16 |
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| Rani Therapeutics Holdings-a SH (RANI) | 0.1 | $12M | NEW | 8.5M | 1.35 |
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| Perceptive Capital Solutions SH (PCSC) | 0.1 | $9.8M | 750k | 13.03 |
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| Adicet Bio SH (ACET) | 0.1 | $8.0M | NEW | 948k | 8.42 |
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| Newamsterdam Pharma Co Nv-27 SH (NAMSW) | 0.1 | $7.7M | 333k | 23.00 |
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| Genedx Holdings Corp SH (WGS) | 0.1 | $7.5M | 58k | 130.06 |
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| Waystar Holding Corp SH (WAY) | 0.0 | $4.7M | NEW | 144k | 32.75 |
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| Werewolf Therapeutics SH (HOWL) | 0.0 | $4.2M | 6.7M | 0.63 |
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| Hinge Health Inc-a SH (HNGE) | 0.0 | $3.7M | NEW | 80k | 46.45 |
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| Progyny SH (PGNY) | 0.0 | $2.5M | 97k | 25.68 |
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| Qiagen SH | 0.0 | $2.1M | NEW | 44k | 47.34 |
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| Orthopediatrics Corp SH (KIDS) | 0.0 | $2.0M | NEW | 110k | 17.76 |
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| Health Catalyst SH (HCAT) | 0.0 | $1.9M | NEW | 794k | 2.39 |
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| Palatin Technologies SH (PTN) | 0.0 | $1.1M | NEW | 70k | 15.38 |
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Past Filings by Ra Capital Management
SEC 13F filings are viewable for Ra Capital Management going back to 2010
- Ra Capital Management 2025 Q4 filed Feb. 17, 2026
- Ra Capital Management 2025 Q3 filed Nov. 14, 2025
- Ra Capital Management 2025 Q2 filed Aug. 14, 2025
- Ra Capital Management 2025 Q1 filed May 15, 2025
- Ra Capital Management 2024 Q4 filed Feb. 14, 2025
- Ra Capital Management 2024 Q3 filed Nov. 14, 2024
- Ra Capital Management 2024 Q2 filed Aug. 14, 2024
- Ra Capital Management 2024 Q1 amended filed May 17, 2024
- Ra Capital Management 2024 Q1 filed May 15, 2024
- Ra Capital Management 2023 Q4 filed Feb. 14, 2024
- Ra Capital Management 2023 Q3 amended filed Nov. 15, 2023
- Ra Capital Management 2023 Q3 filed Nov. 14, 2023
- Ra Capital Management 2023 Q2 filed Aug. 14, 2023
- Ra Capital Management 2023 Q1 filed May 15, 2023
- Ra Capital Management 2022 Q4 filed Feb. 14, 2023
- Ra Capital Management 2022 Q3 filed Nov. 14, 2022